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Your search for "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" yielded 194611 hits

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Objective. To evaluate the Cockcroft - Gault (CG) equation, using various body weight expressions, and the Sawyer equation in predicting glomerular filtration rate (GFR) using an enzymatic and zero-calibrated Jaffe plasma-creatinine assay, and to derive a new robust equation in adults. Material and methods. The CG weight measures included total, ideal and adjusted body weight (ABW; lowest of total

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A dramatic increase in prevalence of pediatric obesity has occurred in most countries over the past few decades. This is of particular significance given the fact that overweight children and adolescents are at increased risk for multiple medical co-morbidities, as well as psychosocial and behavioral difficulties. While considerable attention has recently been paid to identifying obesity and the i

Ökad risk för komplikationer för vuxna med medfödda hjärtfel – Vetenskap och Hälsa

Ökad risk för komplikationer för vuxna med medfödda hjärtfel – Vetenskap och Hälsa Hoppa till innehåll Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Ökad risk för komplikationer för vuxna med medfödda hjärtfel 2021-11-03 Illustration av åderförkalkat kärl. Illustration: Colourbox Personer som framgångsrikt be

https://www.vetenskaphalsa.se/okad-risk-for-komplikationer-for-vuxna-med-medfodda-hjartfel/ - 2026-10-09

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Background: Polymorphism within the same species, population, and sex is an interesting problem for the evolutionary biologist, since differences in fitness between the morphs have to cancel out over evolutionary time, otherwise morphs of lower fitness would become extinct. One way this may be achieved is through the adoption of different morph-specific reproductive strategies, allowing morphs to

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Translocation-associated gene fusions are well recognized in acute myeloid leukemia. Other molecular genetic changes are less well known. The novel cDNA technology has opened the avenue to large-scale gene expression analysis. Our aim was to perform cDNA microarray analysis of acute myeloid leukemia (AML).

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This study shows for the first time that normal brain tissue toxicities after WBI can be reduced with increased dose rate. Spatial memory is preserved after WBI with mean dose rates above 100 Gy/s, whereas 10 Gy WBI at a conventional radiotherapy dose rate (0.1 Gy/s) totally impairs spatial memory.

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BACKGROUND: Remote assessment of respiratory tract infections (RTIs) has been a controversial topic during the fast development of private telemedicine providers in Swedish primary health care. The possibility to unburden the traditional care has been put against a questionable quality of care as well as risks of increased utilization and costs. The covid-19 pandemic has contributed to a changed m

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Evaluation of two rulings of the Court of Justice of the European Union (CJEU) in C-753/18 STIM and SAMI v Fleetmanager and Nordisk Biluthyrning and in C-637/19 BY v CX, both concerning the notion of 'communication to the public' present in Article 3 InfoSoc Directive 2001/29.

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As part of the IEA-SHC Task 41 'Solar Energy and Architecture' an international survey was carried out. This paper presents its results for Subtask B which especially focuses on methods and tools for solar design applied by architects. Building professionals, mainly architects, were contacted via email and asked to participate in a web-based questionnaire about their use of methods and tools for s

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Physical exercise affects hippocampal structure and function, but the underlying neural mechanisms and the effects of exercise intensity remain incompletely understood. Therefore, we undertook a comprehensive, multi-modal 3T and 7T MRI randomized controlled trial (Netherlands Trial Register - NL5847) in which we randomized 52 young, non-athletic volunteers to a 12-week low- or high-intensity exerc

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Objective. To analyse how the main components of the disease phenotype (sicca symptoms, diagnostic tests, immunological markers and systemic disease) can be driven by the age at diagnosis of primary Sjögren's syndrome (pSS). Methods. By January 2021, the participant centres had included 12,753 patients from 25 countries that fulfilled the 2002/2016 classification criteria for pSS. The age at diagn

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Frequent and accurate measurements of inland Water Surface Elevation (WSE) are essential for effective water resource management. However, single-mission satellite altimetry often lacks the temporal resolution needed to capture detailed WSE changes. While multi-mission integration can improve temporal coverage, it is hindered by inter- and intra-mission biases arising from variations in sensor des

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Municipal housing companies have been recognised for their potential in taking on a leadership role in terms of energy efficiency in buildings, raising the question of what the transaction cost barriers are in these companies’ internal operations for undertaking energy efficiency measures. In this study, we thus explore transaction costs barriers in municipal housing companies in Sweden. Data on q

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The intention of present thesis was to investigate the linkages between social capital and household's well-beings in rural fishing community in which a community based a fisher's management project (CBFM) promoted some essential element of social capital such as group association life, level of trust, and mutually benefits collective actions. This paper has brought attention to role of CB

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Key recommendationsPastureland restoration must be implemented to reduce dependency oncoping mechanisms such as emergency feeding, mechanized transport andintense workloads. These coping mechanisms are increasingly used to dealwith the cumulative effects of encroachments from competing land uses,predator pressure, and the impacts of climate change on snow conditions.Vigorous thinning of dense, man

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DNA polymerases make up a family of enzymes responsible for regulating DNA replication and repair, which in turn maintains the integrity of the genome. However, despite intensive kinetic, crystallographic, and computational studies, elucidation of the detailed enzymatic mechanism still presents a significant challenge. We recently developed an alternative strategy for exploring the fidelity and me