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Synthesis of heme A from heme B (protoheme IX) most likely occurs in two steps with heme O as an intermediate. Bacillus subtilis CtaB, an integral membrane protein, functions in farnesylation of heme B to form heme O. CtaA, also a membrane protein, is required for heme A synthesis from heme O and appears to be a monooxygenase and/or a dehydrogenase. Wild-type ctaA and ctaB expressed together from
A highly tunable linear triple quantum dot (TQD) device is realized in a single-crystalline pure-phase InAs nanowire using a local finger gate technique. The electrical measurements show that the charge stability diagram of the TQD can be represented by three kinds of current lines of different slopes and a simulation performed based on a capacitance matrix model confirms the experiment. We show t
PURPOSE: To examine health care use and health care costs among partners of persons with cancer. PATIENTS AND METHODS: Partners of patients with colon, rectal, lung, breast, and prostate cancer (N = 11,076) were identified via linked data from the Tumor Registry of Southern Sweden and Census Registry of Sweden. Health care use, total costs of health care, and diagnosis of the partner were studied
BACKGROUND: Among the textile dyes, disperse dyes are common sensitizers. OBJECTIVE: To investigate whether patch testing with a textile dye mix consisting of eight disperse dyes would be equivalent to testing with the separate ingredients of the mix at the concentrations used in the mix. METHODS: Researchers tested 1,780 consecutive patients with a mix consisting of Disperse Blue 35, Disperse Yel
OBJECTIVE: To compare ambulatory blood pressure recorded during a work day with a leisure day regarding masked hypertension. DESIGN: A randomized crossover study in middle-aged normotensives. PARTICIPANTS: Thirty-seven untreated middle-aged normotensives (17 women), who had repeated office blood pressure less than 140/90 mmHg. MAIN OUTCOME MEASURE: Individual difference of masked hypertension betw
Abstract L-DOPA-induced dyskinesia in Parkinson's Disease (PD) is associated with large increases in brain dopamine (DA) levels following drug dosing, but the precise significance of this phenomenon is not understood. Here we compare DA efflux and metabolism in the striatum and the substantia nigra (SN) in dyskinetic and non-dyskinetic animals following a standard dose of L-DOPA. Rats with 6-OHDA
A statistical model based on four kallikrein markers (total prostate-specific antigen [tPSA], free PSA [fPSA], intact PSA, and human kallikrein-related peptidase 2) in blood can predict risk of Gleason score ≥7 (high-grade) cancer at prostate biopsy.
A miniaturized thermal flow injection analysis biosensor has been coupled with a microdialysis probe for continuous subcutaneous glucose monitoring. Thermal biosensors are based on the principle of measuring the heat evolved during enzyme catalysed reactions. The system presented here consists of a miniaturized thermal biosensor with a small column containing coimmibolized glucose oxidase and
The Arctic is exposed to even faster temperature changes than most other areas on Earth. Constantly increasing temperature will lead to thawing permafrost and changes in the methane (CH4) emissions from wetlands. One of the places exposed to those changes is the Abisko-Stordalen Mire in northern Sweden, where climate and vegetation studies have been conducted since the 1970s. In our study, we anal
What roles are military institutions expected to play in today's rapidly changing security environment? How are they supposed to interact with the society they are tasked to protect? These questions have been posed by classical military sociologists as well as by a newer generation of scholars. Yet so far, a comprehensive mapping of the military's potential roles in contemporary society is missing
Halomonas boliviensis sp. nov. is proposed for two moderately halophilic, psychrophilic, alkalitolerant bacteria, LC1(T) (=DSM 15516(T)=ATCC BAA-759(T)) and LC2 (=DSM 15517=ATCC BAA-760), both of which were isolated from a soil sample around the lake Laguna Colorada, located at 4300 m above sea level in the south-west region of Bolivia. The bacteria are aerobic, motile, Gram-negative rods that pro
In 2009, the 26 years long, brutal Sri Lankan civil war between the separatist terrorist group “Liberation Tigers of Tamil Eelam” (LTTE) and the Sri Lankan government came to an end. The government eradicated the LTTE, and stability was achieved through a so called “victor’s peace”, not followed by any negotiations or agreements between the warring parties. Ethnic divisions still exist in Sri Lank
Research questions: How to implement a traceability system in an automated sanitary ware production system Deliverables: This thesis establishes whether it is cost beneficial to implement a traceability system for an automated sanitary ware production system where there are no legislative requirements. Methodology: The research method that is used in this thesis is a combination of action research
In 2011 the C9ORF72 repeat expansion was identified as the most frequent genetic mutation underlying FTD and ALS. The main aim of this study was to investigate clinical characteristics in a large C9ORF72-positive FTD family, and to compare these with the neuropathological findings.
Purpose – The purpose of this master thesis is to test the applicability of the dashboard development procedure by Vilarinho, Lopes and Sousa (2017) in the application case of a single case study for a redesign of a production dashboard. In doing so a practical new dashboard layout shall be reached, which considers the needs of all dashboard users. Design/methodology/approach – This thesis was co
To the ensure continuity and protection of critical infrastructures in society, it is necessary to study infrastructure dependencies. This thesis focuses on critical infrastructure dependencies in Sweden and aims to increase the knowledge of how municipalities in Sweden analyze critical dependencies in municipal risk and vulnerability analyses (RVAs). The study adopts a framework of risk governanc
Background: Medical treatment of hypertension is not always sufficient to achieve blood pressure control. Despite this, previous studies on supplementary therapies, such as yoga, are relatively few. We investigated the effects of two yoga interventions on blood pressure and quality of life in patients in primary health care diagnosed with hypertension. Methods: Adult patients (age 20-80 years) wit
Creating Non-governmental Self-help groups (SHGs) has been a common thing in India since the early 1990’s. Studies show that the SHGs usually empower their members in different ways. The empirical material being used in this paper consists of one group discussion and twelve semi-structured interviews with members of five different SHGs being organized by a Non governmental organization (NGO) in Mu
The prevalence of HIV has caused adverse impacts on rural households, not least in the northern Vietnam where the problem has become a development issue. Despite a rapid economic growth leading to donor withdrawal, huge income disparities still exists. As a result, a person facing the additional burden of HIV has to cope with an even greater distress than before. The aim of this research was there
