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Factor I (FI) is a crucial inhibitor controlling all complement pathways due to its ability to degrade activated complement proteins C3b and C4b in the presence of cofactors such as factor H, C4b-binding protein, complement receptor 1 or CD46. Complete deficiency of FI, which is synthesized mainly in the liver is rare and leads to complement consumption resulting in recurrent severe infections, gl
Background. The SWENOTECA IV protocol from 1995 is a prospective population-based study in metastatic non-seminomatous germ cell testicular cancer (NSGCT), designed for early identification of patients with poor response to standard cisplatin-based chemotherapy. A slow tumor marker decline (HCG T(1/2) > 3 days, AFP T(1/2) > 7 days) after BEP or BEP plus ifosfamide was regarded as poor response. Th
Measurements of cross sections for events with charm and beauty jets in deep inelastic scattering at HERA are presented. Events with jets of transverse energy E-T(jet) > 6 GeV and pseudorapidity - 1.0 < eta(jet) < 1.5 in the laboratory frame are selected in the kinematic region of photon virtuality Q(2) > 6 GeV2 and inelasticity variable 0.07 < y < 0.625. Measurements are also made requiring a jet
Henning M., Stam E. and Wenting R. Path dependence research in regional economic development: cacophony or knowledge accumulation, Regional Studies. The concept of path dependence has gained momentum in the social sciences, particularly in economic geography. This paper explores the empirical literature on path dependence and path creation in regional economic development. It offers a critical ref
Background. Linear programming has been used extensively as a tool for nutritional recommendations. Extending the methodology to food formulation presents new challenges, since not all combinations of nutritious ingredients will produce an acceptable food. Furthermore, it would help in implementation and in ensuring the feasibility of the suggested recommendations. Objective. To extend the previou
Background: Our aim was to compare the effects of a Paleolithic ('Old Stone Age') diet and a diabetes diet as generally recommended on risk factors for cardiovascular disease in patients with type 2 diabetes not treated with insulin. Methods: In a randomized cross-over study, 13 patients with type 2 diabetes, 3 women and 10 men, were instructed to eat a Paleolithic diet based on lean meat, fish, f
Liming is used to counteract forest decline induced by soil acidification. It consists of Ca and Mg input to forest soil and not only restores tree mineral nutrition but also modifies the availability of nutrients in soil. Ectomycorrhizal (ECM) fungi are involved in mineral nutrient uptake by trees and can recover them through dissolution of mineral surface. Oxalate and siderophore secretion are c
Study objectives: A method for medication reconciliation that reduces medication errors and healthcare contacts when a patient is discharged from hospital, LIMM-DI (Lund integrated medicines management-discharge information) had been previously developed by the authors. LIMM-DI is structured information written for the patient and sent to the next caregiver. In this study, the use (implementation
Experimental study of the phase transition in the lithium-excess lithium-manganese spinel over the pressure range 0-13 GPa has shown its suppression. This observation implies that the Li/Mn ratio, associated with the manganese oxidation state, plays an important role in the high-pressure phase transformation of the lithium-manganese spinels. As indicated by the results, the occupation of the octah
Abstract in UndeterminedPrevious research has shown that the intentional suppression of unwanted memories can lead to forgetting in later memory tests. However, the mechanisms underlying this effect remain unclear. This study employed recognition memory testing and event-related potentials (ERPs) to investigate whether intentional suppression leads to the inhibition of memory representations at an
Optical spectral analysis and multispectral imaging provide powerful means for characterizing samples in a wide variety of applications and on many spatial scales. We present a simple implementation of these techniques in the context of microscopy. A modified commercial microscope equipped with a CMOS imaging detector, combined with an array of light emitting diodes with emission ranging from ultr
Measurement of haemoglobin (Hb) adducts from acrylamide (AA) and its metabolite glycidamide (GA) is a possibility to improve the exposure assessment in epidemiological studies of AA intake from food. This study aims to clarify the reliability of Hb-adduct measurement from individual single samples for exposure assessment of dietary AA intake. The intra-individual variations of AA- and GA-adduct le
Current theoretical attempts to understand the reversible formation of stable microtubules and virus shells are generally based on shape-specific building blocks or monomers, where the local curvature of the resulting structure is explicitly built-in via the monomer geometry. Here we demonstrate that even simple ellipsoidal colloids can reversibly self-assemble into regular tubular structures when
This work treats the estimation of the chromagram for harmonic audio signals using a block sparse reconstruction framework. Chroma has been used for decades as a key tool in audio analysis, and is typically formed using a Fourier-based framework that maps the fundamental frequency of a musical tone to its corresponding chroma. Such an approach often leads to problems with tone ambiguity, which we
The effect of temperature on the adiabatic laminar burning velocities of CH4 + air and H-2 + air flames was analyzed. Available measurements were interpreted using correlation S-L = S-LO (T/T-o)(alpha). Particular attention was paid to the variation of the power exponent a with equivalence ratio at fixed ( atmospheric) pressure. Experimental data and proposed empirical expressions for a as a funct
Background: Vietnam introduced the Health Care Fund for the Poor in 2002 to increase access to health care and reduce the financial burden of health expenditure faced by the poor and ethnic minorities. It is often argued that effects of financing reforms take a long time to materialize. This study evaluates the short-term impact of the program to determine if pro-poor financing programs can achiev
The Novato L6 chondrite fragmental breccia fell in California on 17 October 2012, and was recovered after the Cameras for Allsky Meteor Surveillance (CAMS) project determined the meteor's trajectory between 95 and 46 km altitude. The final fragmentation from 42 to 22 km altitude was exceptionally well documented by digital photographs. The first sample was recovered before rain hit the area. First
Popular Abstract in Swedish När patienten lämnar sjukhuset och återvänder hem efter en operation för kolorektal cancer (tjocktarm och ändtarm) innebär det en stor omställning. De är inte återställda efter den stora bukoperationen och upplever olika symtom som smärta, tarmbesvär och stor trötthet. Eftersom vårdtiderna blir allt kortare har deras återhämtning bara påbörjats på sjukhuset och de kommeThe overall aim of this thesis is to study the experiences of patients and next of kin with regard to information and information needs after being discharged after colorectal cancer surgery. The aim was also to study factors related to this. Different methods were combined in this explorative study in order to obtain diverse types of data. Patients who had undergone surgery for colorectal cancer
