Head and neck cancer is a heterogeneous group of tumours, although histopathologically, >95% are squamous cell carcinomas (SCC). Some tumours respond better to therapy than others. Not enough is known to predict the outcome and tailor individualised treatment. Although one of the main risk factors, smoking, has decreased over the last decades, some head and neck cancer groups show increasing incid

OBJECTIVE-This study assessed insulin and glucagon secretion in relation to insulin sensitivity in Caucasian women who develop impaired glucose tolerance (IGT) versus those who maintain normal glucose tolerance (NGT) over a 12-year period. RESEARCH DESIGN AND METHODS-At baseline and after 3, 8, and 12 years, glucose tolerance (75-g oral glucose tolerance test), insulin sensitivity (euglycemic-hype

We describe quantum-size and binding-site effects on the chemical and local field enhancement mechanisms of surface-enhanced resonance Raman scattering (SERRS), in which the pyridine molecule is adsorbed on one of the vertices of the Ag-20 tetrahedron. We first investigated the influence of the binding site on normal Raman scattering (NRS) and excited state properties of optical absorption spectro

Recently, the possibility of misrepresentation has resurfaced in the debate between higher-order thought theorists and their opponents. One new element in the debate has been the rare cases of Charles Bonnet syndrome (RCB cases), proposed as empirical evidence for misrepresentation as posited by the higher-order theories. In this article I will spell out the argument supposedly underlying the clai

Objectives To describe the gray-scale and vascular characteristics of endometrial cancer in relation to stage, grade and size using two-dimensional (2D)/three-dimensional (3D) transvaginal ultrasound. Methods This was a prospective multicenter study including 144 women with endometrial cancer undergoing transvaginal ultrasound before surgery. The sonographic characteristics assessed were echogenic

Cohorts comprising fishermen's families on the east coast of Sweden have been found to have a high consumption of contaminated fish as well as high body burdens of persistent organochlorine pollutants (POPs). Their west coast correspondents are socio-economically similar, but with considerably lower POP exposure since the fish caught on the west coast is far less contaminated. The rationale for th

This dissertation investigates references to five mythological characters (Penelope, Laodamia, Andromache, Alcestis and Euadne) used as paragons of wifely virtues in Roman elegy. Providing extensive close readings, it discusses the usage of these five characters in the works of Propertius and Tibullus, and in the elegiac works of Ovid, with special reference to issues of narratology, intertextuali

Traditionally, heavy-duty diesel engines have high efficiencies but also high emissions of NOx and soot particles. New engine concepts show the potential to retain diesel-like efficiencies while reducing emissions by forming a completely or partially homogeneous mixture of fuel and air prior to ignition through compression. The long ignition delay required to form this homogeneous mixture makes th

Purpose: Glucose concentrations are elevated in retinal cells in undiagnosed and in undertreated diabetes. Studies of diabetic patients suggest that retinal function adapts, to some extent, to this increased supply of glucose. The aim of the present study was to examine such adaptation in a model of type 2 diabetes and assess how the retina responds to the subsequent institution of glycemic contro

The genetic background may influence methylmercury (MeHg) metabolism and neurotoxicity. ATP binding cassette (ABC) transporters actively transport various xenobiotics across biological membranes.

In this paper we present the first core-level photoelectron spectroscopic study of solid nanoparticles in liquid water. The particles are SiO2-based with an average diameter of 70 nm and functionalized with carboxylic groups. Despite that the sample is very dilute, we show that it is possible to obtain reasonable photoemission signal containing chemical information about both the ligands and the o

Boken, som är en slutrapport över forskningsprojektet Förintelsen och den europeiska historiekulturen, rör frågan hur förintelsehistorien har uttolkats, representerats och brukas i olika samhällen och stater i efterkrigstidens Europa, med tonvikt på de senaste decennierna.

The contiguity and phase of sequence information are intrinsic to obtain complete understanding of the genome and its relationship to phenotype. We report the fabrication and application of a novel nanochannel design that folds megabase lengths of genomic DNA into a systematic back-and-forth meandering path. Such meandering nanochannels enabled us to visualize the complete 5.7 Mbp (1mm) stained DN

High and low pollen deposition years in the period 1998-2010 were recorded for ten forest-forming trees in Roztocze (SE Poland) using Tauber-style traps. The coincidence of very high/low pollen deposition years recorded in Tauber traps and aerobiological data obtained by volumetric samplers shows that these phenomena occur simultaneously in different places across vast areas of a tree's distributi