OBJECTIVES: To explore the relationship between genetic background and antibody levels in a nondiabetic population. We evaluated if high levels of autoantibodies against the 65 kDa isoform of glutamic acid decarboxylase (GAD65Ab), were associated with high-risk genes, i.e. HLA, CTLA-4 and INS VNTR genes. DESIGN AND SUBJECTS: Seventy-five (M/F 39/36) subjects exceeding the 95th percentile of GAD65

The clinical pharmacology of desmopressin and a new vasopressin analogue (F992) was investigated in healthy human subjects. The common procedure of overhydration of healthy volunteers when studying the antidiuretic effect of a drug, may affect the pharmacokinetics, in particular the volumes of distribution. Hence, the estimated parameters may not be relevant to euhydrated patients. F992 was found

Popular Abstract in Swedish Medfödda hjärtfel (congenital heart defects,CHD) förekommer hos nästan 1 % av alla födda barn. En del lindriga hjärtfel spontanläker, men de flesta hjärtfel måste opereras i läkande eller lindrande syfte. Stora kirurgiska framsteg har gjorts på senare år. Hjärtfel som tidigare icke ansågs möjliga att åtgärda kan nu opereras, och många operationer utföres tidigt i livet,The aim of this study was to evaluate new MR techniques permitting qualitative and quantitative analysis of cardiac function and measurement of velocity and flow, and later on contrast-enhanced MR angiography, techniques largely unexplored in children with CHD. Infants with tetralogy of Fallot and pulmonary atresia with ventricular septal defect were examined pre-operatively. MRI was found to be a

One of the challenges that must be overcome to realize the practical benefits of ad hoc networks is quality of service (QoS). However, the IEEE 802.11 standard, which undeniably is the most widespread wireless technology of choice for WLANs and ad hoc networks, does not address this issue. In order to support applications with QoS requirements the upcoming IEEE 802.11e standard enhances the origin

Many control systems have a global dynamical behavior that in addition to a desired stable equilibrium has one or more unstable equilibria or other exceptional trajectories. Typical examples of such systems are pendulums or so called phase locked loops. The objective of the paper is to compare two different methods for analysis of the global behavior in such systems. The first method is LaSalle's

Yta är, paradoxalt nog, ofta något grundläggande i receptet för framgång i dagens ekonomiska system. Utseende, klädsel, attityd och attribut är centrala element i det som Erving Goffman kallar impression management: förmågan att avge ”rätt” intryck med hjälp av välformulerade självpresentationer som, baserade på statussymboler och associationer, indikerar vem man är eller vill vara (se Goffman 195

Geometric reconstruction from image collections is a classical computer vision problem. The problem essentially consists of two steps; First, the identification of matches and assembling of point tracks, and second, multiple view geometry computations. In this paper we address the problem of constructing point tracks using graph theoretical algorithms. From standard descriptor matches between all

Popular Abstract in Swedish En kontinuerlig alkoholkonsumtion leder till en ökad tolerans för alkohol (dvs en allt större dos krävs för att uppnå samma effekt) och kan slutligen också leda till ett alkoholberoende. Alkoholism är ett betydande samhällsproblem och en personlig tragedi för de som drabbas och deras omgivning. Alkohol har till skillnad från andra beroendeframkallande droger som tex koAlcohol induces profound effects on the function of the nerve cells in the nervous system. Alterations in gene expression is an important way by which these effects could be induced and sustained. Activating Protein-1 (AP-1) is a dimeric transcription factor constituted of proteins from the fos and jun immediate-early gene families. AP-1 induces gene expression of genes having a functional AP-1 bi

Öppna digitala lärresurser är resurser som finns tillgängliga på Internet, att användas och oftast även att bearbetas fritt. Det kan vara inspelade föreläsningar, powerpoint-presentationer, avancerad simulering eller interaktiva quizzar. Lärare har fram till idag producerat 1.5 miljoner lärresurser, fritt tillgängliga i olika portaler, t ex iTunes U, YouTube Edu, Open University Learning Space och