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The development of inhibitory antibodies against coagulation factor VIII (FVIII) in patients with mild haemophilia A is uncommon. We describe here two families in which three or two members have developed inhibitors, suggesting a familial predisposition. The mutations found, in the A2 (Arg593Cys) and C1 domains (Tyr2105Cys), have been reported to give rise to inhibitor development in single indivi

Measurements are presented of inclusive charm and beauty cross sections in e(+)p collisions at HERA for values of photon virtuality 12 <= Q(2) = 60 GeV2 and of the Bjorken scaling variable 0.0002 <= x <= 0.005. The fractions of events containing charm and beauty quarks are determined using a method based on the impact parameter, in the transverse plane, of tracks to the primary vertex, as measured

The Arctic has become an important region in which to assess the impacts of current climate variability and amplification of projected global warming. This is because i) the Arctic has experienced considerable warming in recent decades (an average of about 3°C and between 4° and 5°C over much of the landmass); i) climate projections suggest a continuation of the warming trend with an increase in me

To clarify the effects of solid fat and liquid oil on dough in more detail in a simpler system, gluten-starch doughs with different gluten contents were investigated. The results from rheological measurements indicate that dough with a higher starch content has less resistance to strain and dough with a lower starch content has a rubber-like structure. The effects of the physical state of nonpolar

The anti-inflammatory effect of purified honey bee venom (HBV) was studied using a recently described animal model in which preformed immune complexes were injected into rabbit knee-joints. As little as a single injection of 1.2 micrograms HBV/kg body weight subcutaneously significantly reduced the immune complex induced joint inflammation as measured by reduction in leukocyte counts in the joint

In this study changes in the diameter and compliance of the distal abdominal aorta (76 healthy Caucasian males, 5-71 years old) were determined non-invasively and related to age by means of an ultrasound phase-locked echo-tracking system. The diameter of the aorta increased not only in the period between 5 and 25 years of age, but also by about 30% between the ages of 25 and 71. The pressure diame

A convenient synthesis of benzene-1,3,5-tricarbaldehyde was developed as well as benzaldehyde derivatives carrying one or two latent aldehyde groups. The asymmetric derivatives may serve as versatile scaffolds for the synthesis of sectorial dendrimers and multifunctional molecules.

The JastAdd system enables modular specifications of extensible compiler tools and languages. Java has been extended with the Rewritable Circular Reference Attributed Grammars formalism that supports modularization and extensibility through several synergistic mechanisms. Object-orientation and static aspect-oriented programming are combined with declarative attributes and context-dependent rewrit

Papers: - Early age chemical shrinkage and autogenous deformation of cement pastes. - Shrinkage of high-strength concrete at different ambient humidities. - A computer program to calculate drying of and desiccation in concrete. - Aspects of monitoring moisture changes using electrical impedance spectroscopy. - A Nordtest method for verification of self-desiccation in concrete. - Early age autogeno

This project is a continuation of the research project: Public transport in Dar-es-Salaam, Tanzania; institutional challenges and opportunities for a sustainable transport system carried out from 2003 to 2004. This study analyses mechanisms, forms for involvement and participation in planning for public transport. Questions asked are: How can participatory transport planning involving the supplier

Experiments were performed to define quantitatively the substrate (K(+) and Cl(-)) dependence of the transport function (production of equally large and oppositely directed K(+)and Cl(-) flows/currents) of an earlier (Theander et al., 1999) identified electroneutral K-Cl cotransporter in the slowly adapting stretch receptor neurone of the European lobster. The experiments were based on microelectr

Popular Abstract in Swedish Skulle p53-målgenen TRIM22 kunna skydda mot cancer uppkomst? Frisk blodbildning En frisk vuxen människa har mellan fyra och sex liter blod, beroende på individens kroppsstorlek. Blodet produceras i benmärgen som finns i skelettbenen. Varje sekund bildas normalt i benmärgen tre till fyra miljoner blodkroppar från våra stamceller. Blodkropparna är specialiserade celler The tumor suppressor gene p53 is a transcription factor that mediates cell cycle arrest, apoptosis and differentiation. p53 mediated differentiation of leukemic cells depends on the transcriptional activity of p53 but so far no obvious differentiation inducing target gene has been identified. Using a cDNA microarray analysis, I identified TRIM22/Staf50 as a novel direct target gene to p53. The fun

In this paper stability and dynamic properties of voltage and frequency droop control of power electronic converters are investigated for a distributed generation system. Droop control is utilized to share active and reactive power among the source converters. The voltage and frequency controllers are designed so that stand-alone converter operation feeding constant power loads performs satisfacto

A diffusion cell has been used to measure the effective diffusion coefficients of proteins. The method is applied to lysozyme and BSA at different pH and ionic strength. A parameter optimization technique is used to estimate the diffusion coefficients directly from experimental data. The importance and influence of pH and ionic strength on the diffusive properties in an agarose gel have been demon

Popular Abstract in Swedish En ny typ av reaktor för kemikalie och läkemedelsproduktion är under utveckling av Alfa Laval AB, ett svenskt företag som är en världsledande tillverkare av värmeväxlare. Den nya reaktortypen, som kallas för plattreaktor, kombinerar den höga värmeöverföringsförmågan från plattvärmeväxlaren med den effektiva mikro-mixningen av kemikalier som är typisk för en mikro-reaktoA new chemical reactor, the Alfa Laval Plate Reactor, is being developed by Alfa Laval, a Swedish world-leading heat exchanger company. The plate reactor combines the high-heat-transfer capabilities of plate heat exchangers with the efficient mixing and reaction control typical of microreactors. With this new concept, highly exothermic reactions can be produced using more concentrated reactants an