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An automated platform for accelerating and focusing adaptive laboratory evolution

The rate of change in adaptive laboratory evolution (ALE), in which a population of microorganisms is continuously cultivated under a specific selective pressure, is controlled by the cellular mutagenesis rate and the randomness of where in the genetic material mutations are introduced. The constant selection pressure makes it a crucial, yet slow, method in developing microorganisms with novel phe

Denial is a pipeline in Canada : a feminist critical discourse analysis of Canadian far-right climate obstruction

Climate denial and refusal remain central to the ontologies of far-right political projects in many of the countries most responsible for rising temperatures. This article demonstrates how misogyny facilitates the proliferation of obstructionist rhetoric. Specifically, the People’s Party of Canada’s (PPC) climate discourse is analyzed through a feminist lens anchored in Gramscian theorisations of

Covalent Stabilization of Collagen Mimetic Triple Helices and Assemblies by Dopa Crosslinking

Creating thermally stable collagen mimetic peptides (CMPs) is a persistent challenge. Nature leverages covalent crosslinkings to stabilize collagen's signature triple helical tertiary structure and higher-order assemblies. Herein, crosslinkings between levodopa (Dopa) and lysine can covalently stabilize the triple helix in CMPs is demonstrated. Since alkaline conditions catalyze the oxidation of t

The Syneresis of Rennet-Coagulated Curd

Gels formed from milk by renneting or acidification under quiescent conditions may subsequently show syneresis, that is, expel liquid (whey) because the gel (curd) contracts. Under quiescent conditions, a rennet-induced milk gel may lose two-thirds of its volume, and up to 90%, or even more, if external pressure is applied. Often, syneresis is undesired, for example, during storage of products lik

Optimization of multi-column chromatography for capture and polishing at high protein load

Integrated Continuous Biomanufacturing reduces manufacturing costs while maintaining product quality. A key contributor to high biopharmaceutical costs, specifically monoclonal antibodies (mAbs), is chromatography. Protein A ligands are usually preferred but still expensive in the manufacturing context, and batch chromatography under-utilizes the columns' capacity, compromising productivity to mai

Evaluating Electric Road Systems for Freight Transport in Sweden : A Simulation-Based Study on Trans-European Transport Network

The electrification of long-haul freight transport is essential for reducing emissions and achieving sustainable mobility. However, battery-electric trucks (BETs) face significant barriers, including limited range, high battery weight, and prolonged charging times, which hinder their widespread adoption for long-distance travel. Electric Road Systems (ERS) offer a compelling solution by providing

Contesting agrarian futures : Structural contradictions and collective struggle among smallholder farmers

Jordbruk och jordbruksomvandling är centrala i debatten om försörjning, utveckling och hållbarhet, särskilt i det globala syd där de förs fram som vägen till fattigdomsbekämpning, livsmedelssäkerhet och ekonomisk omvandling. Trots årtionden av reformer fortsätter jordbruksutvecklingen dock att ge ojämna och motstridiga resultat. Politik för social inkludering, landsbygdsomvandling och hållbarhet bAgriculture remains central to global debates on livelihoods, development, and sustainability, particularly across the Global South where it is widely promoted as a pathway to poverty reduction, food security, and economic transformation. Yet, despite decades of reform, agricultural development continues to generate uneven and contradictory outcomes. Policies framed around inclusion, rural transfo

Primary care rehabilitation after Knee Replacement – a cross sectional study

Background: Rehabilitation after Knee Replacement (KR) surgery often entails an extensive rehabilitation in primary care but evidence-based high-quality guidelines are lacking. There is also a knowledge gap regarding current rehabilitation modalities applied in primary care in Sweden. This study aimed to (I) describe rehabilitation in primary care after KR and (II) explore phys-iotherapists’ perce

European Resuscitation Council and European Society of Intensive Care Medicine guidelines 2025 : post-resuscitation care

The European Resuscitation Council (ERC) and the European Society of Intensive Care Medicine (ESICM) have collaborated to produce these post-resuscitation care guidelines for adults, which are based on the International Consensus on Cardiopulmonary Resuscitation Science with Treatment Recommendations (CoSTR) pubished by the International Liaison Committee on Resuscitation (ILCOR). The topics cover

Predictors of giant cell arteritis in patients with polymyalgia rheumatica in southern Sweden—a retrospective study

Objective: To identify predictors of GCA in patients with PMR. Methods: Patients with PMR were identified among participants in two population-based health surveys. Those with a registered diagnosis indicating PMR in national and regional registers (the latter including primary care) were included. Medical records from hospitals and primary care were systematically reviewed. PMR diagnoses were ver

Safe system implementation in three African and three European countries : Preliminary results from a comparison of six countries

The study provides preliminary results from a case comparison of road safety management in three African countries (Tanzania, Ghana, Zambia) with three EU countries, all with a great track record of excellence in traffic safety and practicing Safe Systems principles (Norway and Netherlands & Sweden), based on document analysis and qualitative interviews. Norway, Sweden, and The Netherlands are

Navigating technological change : Future imaginaries and everyday practices in world politics

During the last decade or so, most aspects of world politics have become saturated with digital-technological devices and platforms such as smartphones and social media. Yet, practice-oriented International Relations (IR) scholarship has not adequately accounted for the profound impact of this technological transformation on how world politics is ‘done’ within, across and beyond the traditional in

Barns röster om rädsla och oro i samband med operation

Bakgrund:Rädsla och oro är vanligt förekommande hos barn i samband med sjukvård och förekommer ofta i perioperativa samband. Detta kan leda till negativa fysiologiska och psykologiska konsekvenser. Inom den perioperativa vården är det därför centralt att uppmärksamma och bemöta barnets upplevelser. Utifrån ett barncentrerat perspektiv är det därför viktigt att öka kunskapen om hur barn själva besk

Barnmorskors erfarenheter av att vårda kvinnor i samband med abort

Bakgrund: Abortvården i Sverige är säker, laglig och följer WHO:s riktlinjer. Fri abort gäller fram till graviditetsvecka 18+0, och medicinsk abort är den vanligaste metoden. Barnmorskan har en nyckelroll i hela processen, från information och behandling till preventivmedelsrådgivning och eftervård. Vården utgår från ett personcentrerat förhållningssätt där kvinnans autonomi och information är cen

Barns upplevelser vid nålrelaterade procedurer inom hälso- och sjukvården.

Bakgrund: Barnsjuksköterskans arbete ska präglas utifrån aktuella lagar, kompetensbeskrivning och riktlinjer. Barncentrerad vård utgår från barnet som en unik individ med rättigheter, önskemål och erfarenheter. Nålrelaterade procedurer är vanligt förekommande inom hälso- och sjukvården där ofta obehagliga känslor kan upplevas. Barnens reaktioner varierar utifrån ålder och mognad. Hur barn bemöts,

Elevated Impressions: Self-Reported Lasting Effects of Cannabis-Induced Psychedelic Experiences (CIPEs)

Cannabis är en av de mest använda psykoaktiva substanserna i världen och har en lång historia av ceremoniellt bruk som växtmedicin i olika kulturer. På senare år har forskning visat att cannabis kan framkalla psykedeliska tillstånd liknande sådana som medierar den terapeutiska effekterna hos klassiska psykedeliska substanser såsom psilocybin, LSD och ayahuasca. Detta väcker frågor om de långsiktigCannabis is among the most widely used psychoactive substances worldwide and has a long history of ceremonial use as plant medicine across cultures. Recent research indicates that cannabis can, under som circumstances, induce psychedelic states similar to those mediating the therapeutic effects of classical psychedelics. This raises questions about the lasting psychological impact and psychotherap