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Retinitis pigmentosa (RP) is an inherited blinding disease for which there is no treatment available. It is characterized by a progressive and neurodegenerative loss of photoreceptors but the underlying mechanisms are poorly understood. Excessive activation of the enzyme poly(ADP-ribose) polymerase (PARP) has recently been shown to be involved in several neuropathologies. To investigate the possib
Methods of analysing and interpreting two-dimensional velocity field data in order to understand the scales of turbulence of bubbly two-phase flow were developed. Reynolds decomposition and large eddy simulation (LES) decompositions (low-pass filtering), in conjunction with proper orthogonal decomposition (POD) energy spectra analysis, as well as adjusted convective decomposition (constant convect
Solid waste collection and hauling account for the greater part of the total cost in modern solid waste management systems. In a recent initiative, 3300 Swedish recycling containers have been fitted with level sensors and wireless communication equipment. thereby giving waste collection operators access to real-time information oil the status of each container. In this study. analytical modeling a
Apolipoprotein RI (apoM) is a novel apolipoprotein that is predominantly present in high-density lipoprotein, Sensitive sequence starches, threading and comparative model building experiments revealed apoM to be structurally related to the lipocalin protein family. In a 3D model, characterized by an eight-stranded anti-parallel beta -barrel, a segment including Asn135 could adopt a closed or open
We describe the design of the secondary pion beam-line installed at the SIS 18Tm synchrotron at GSI, Darmstadt, and discuss the commissioning results. The experiments were performed with proton and C-12 primary beams at several energies using beryllium production targets. Pion yields in a momentum range between 0.4 and 2.8 GeV/c were identified, At the highest primary beam energies of 3.5 GeV for
The article presents an analysis of the status of Swedish in relation to the use of English in Sweden and gives some examples to show that Swedish as a national language is losing some functional domains to English. Based on basic democracy principles and the need for effective communication some arguments are given for a national policy to guarantee the status of Swedish and how such a policy cou
Popular Abstract in Swedish Äldre personer som erhåller permanent hjälp i sitt dagliga liv har ökat i takt med att livslängden ökat. Många äldre personer kommer troligen framöver att erhålla hjälp i sitt ordinära boende, eftersom den kommunala vården och omsorgen framför allt inom särskilt boende har minskat i omfattning i förhållande till antalet äldre över 65 år. Svensk policy strävar mot att alThe aim of this thesis was to investigate self-reported diseases and complaints, quality of life (QoL), help received with activities of daily living among older people and in relation to who provided the help, and in comparison with those without ADL help. The aim was also to investigate older people’s experiences of receiving help. Data were collected using postal questionnaires in two populatio
To explore the spatial variation of the soil microbial community within a mixed Norway spruce-birch stand, and to test if the spatial patterns of the microbial community are related to the position of trees, we sampled the forest floor at two spatial scales and used the phospholipid fatty acid (PLFA) patterns as indicators of the microbial community structure. Of the 32 most common PLFAs, 20 (62%)
BACKGROUND: Development of proximal and distal colorectal cancers involve partly different mechanisms associated with the microsatellite instability (MSI) and the chromosomal instability (CIN) pathways. Colorectal cancers in patients under 50 years of age represent about 5% of the total number of tumors and have been associated with an increased frequency of MSI tumors. However, MSI and CIN may pl
We have made in situ investigations of epitaxial ultrathin Fe films on Ag(100). This system is known to exhibit a reorientation of the magnetization, dependent of Fe thickness and temperature. Our aim here is to correlate the local structure with the magnetic properties of this system. The X-ray absorption fine structure has been recorded in situ both in the near edge as well as in the extended X-
Growth and metabolic activities of Bacillus cereus were found to cause the extraction of iron atoms from the octahedral position in mica in the kaolin sample (49%) and in the quartz sands sample (17%) after 3 months of bioleaching, while aluminium removal was only 5%. Mica destruction was detected in kaolin and quartz sands samples by X-ray diffraction analysis and also by i.r. adsorption spectros
BACKGROUND: migration and kinking of stent-grafts can occur late after endovascular aneurysm repair. It is unknown if endovascular grafts incorporate enough to be permanently anchored. In this report, healing of aortic stent-grafts was assessed in humans. PATIENTS AND METHODS: we retrieved 23 Dacron stent-grafts from patients treated for an aortic aneurysm since 1993. Twelve stent-grafts were expl
Propagation of transverse electric and magnetic (TEM) pulses in nonstationary, linear, homogeneous, and isotropic dielectric and magnetic materials is investigated using an exact wave splitting. Key intrinsic properties are the index of refraction and the relative admittance, which are both temporal integral operators with kernels that depend on two time variables. In addition, the Sommerfeld fore
