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BACKGROUND: Seizure duration during electroconvulsive therapy (ECT) correlates with treatment efficacy and may be influenced by depth of anaesthesia. The Patient State Index (PSi), derived from processed EEG, offers a potential method to monitor depth of anaesthesia during ECT. This study examined the correlation between pre-ictal PSi and EEG-seizure duration.METHODS: In this prospective observati
Background/Objectives: Older patients are more susceptible to the process of understanding and retrieving information. To provide adequate preoperative information, reduce their vulnerability and anxiety, and thereby facilitate pre-, intra-, and postoperative care, the adoption of new information technologies is essential. This study aimed to explore elderly patients' experiences and perceptions o
For the development of a joint European capacity for monitoring CO2 emissions, we created the framework “CO2 Monitoring Challenges City Mapbooks v1.0” (CMC-CITYMAP). It includes a Jupyter notebook tool (Storm et al., 2025a, https://doi.org/10.18160/P8SV-B99F) which we use to characterise and cluster cities based on aspects relevant for different CO2 monitoring challenges. These include:a. determin
This study aimed to test and validate a dual-time-window (DTW) protocol for 6-(fluoro-18F)-3-(1H-pyrrolo[2,3-c]pyridin-1-yl)isoquinolin-5-amine ([18F]MK6240) dynamic PET imaging in experimental datasets acquired in human subjects. Methods: DTW protocols were tested and validated in datasets previously collected in 25 participants: 13 were cognitively normal, 10 had mild cognitive impairment, and 2
OBJECTIVES: Opioid-free anesthesia (OFA) is a promising alternative to traditional opioid-based anesthesia. Research indicates that OFA reduces postoperative opioid consumption and related adverse effects while maintaining effective pain control and patient safety. Despite these benefits, clinical adoption of OFA remains limited, possible due to gaps in evidence. To bridge this knowledge gap, a we
BACKGROUND: Monitoring of vital signs is essential in anaesthesia care and plays a key role in preventing adverse events. Technological innovation is recognised as an important factor in enhancing patient safety. Smart glasses represent a novel tool that may support anaesthesia professionals in monitoring vital signs; however, their practical use and user experiences in anaesthesia care remain ins
The increasing presence and activities of people in both urban environments and non-urban areas result in the exposure of many wild animal populations to persistent human disturbance. As a response, individuals in disturbed populations often become tolerant towards humans, which can have significant ecological and societal consequences, for example by affecting ecosystem services and human–wildlif
Micropollutants in wastewater can persist through conventional treatment, threatening ecosystems and human health through toxicity, bioaccumulation, and disruption of biological processes. Limited monitoring, due to cost and methodological challenges, allows these compounds to go undetected, potentially leading to long-term, irreversible impacts. To address this, modern wastewater treatment plants
The presence of pharmaceuticals, especially antibiotics, in aquatic environments can significantly contribute to the rise of antibiotic resistance, presenting a critical global public health challenge. This study investigates the presence of four selected antibiotics and an antiretroviral drug (nevirapine) in the Vaal River in South Africa. Grab samples collected at nine sampling sites across four
Background: Wrist osteoarthritis (OA) is mainly posttraumatic, affects younger individuals than other types of OA, and can lead to significant disability. The first-line treatment is patient education and exercise, but surgery may be considered if symptoms persist. A mini-invasive surgical approach for wrist OA is partial wrist denervation, which,in theory, alleviates pain by resecting sensory ner
We present a new suite of edge ('Engineering Dwarfs at Galaxy formation's Edge') cosmological zoom simulations. The suite includes 15 radiation-hydrodynamical dwarf galaxies covering the ultrafaint to the dwarf irregular regime () to enable comparisons with observed scaling relations. Each object in the suite is evolved at high resolution () and includes stellar radiation, winds, and supernova fee
We explore the decay of free neutrons into exotic long-lived particles, whose decays could be detected in the next-generation free neutron experiments. We show that such a possibility is viable as long as the exotic particle is highly mass-degenerate with the neutron, avoiding exclusion by large-volume detectors. We estimate the number of observable events and identify the most promising final sta
Designkort/tankekort avsedda att användas som stöd för universell utformning i plan- och byggprocesser
Chains of tasks are ubiquitous and used in a broad spectrum of applications. In these chains, tasks execute according to their timing. Then, they communicate by writing to and reading from shared memory. The schedule of tasks and the read/write instants are naturally subject to uncertainties (variability in the execution time, interference due to shared resources of higher priority tasks, etc.). D
In contemporary Sri Lanka, nationalistic Sinhala organizations like Bodu Bala Sena (BBS) have made a great impact on the debate over what role Buddhism should play in the country. BBS claims that Islam is a non-Sri Lankan element in the Buddhist majority society, campaigning on such issues on social media between 2012 and 2014. This led Sri Lankan Muslim organizations to use social media to counte
