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Bacterial abundance, production and organic carbon limitation in the Southern Ocean (39-62 degrees S, 4-14 degrees E) during the austral summer 1997/1998

Bacterial abundance and production were studied in different zones in the Southern Ocean (39-62degreesS, 4-14degreesE) during a cruise in December-January 1997/1998. The role of potential growth limitation of bacteria due to limited availability of organic carbon (glucose) or inorganic N and P was studied in parallel. A positive correlation between surface water temperatures (-2 to 18 degreesC) an

Digital scoring of haemophilic arthropathy using radiographs is feasible

Radiographs are important tools to evaluate structural changes in many Joint diseases. In the case of haemophilic arthropathy (HA), the Pettersson score is widely used. The rising of digital radiography enables evaluation of these changes in a more quantitative and detailed manner, potentially improving diagnosis and follow-up. The aim of this study was to evaluate whether digital image analysis i

A prospective double blind randomized study comparing the need for blood transfusion with terlipressin or a placebo during early excision and grafting of burns

Introduction: Early excision and skin grafting has become the standard of good burn management, but it is associated with major blood loss. Aim: To determine the haemostatic effect of terlipressin compared with placebo. Material and methods: Fifty-one patients with bums of 10-20% total body surface area had early excision and split skin grafting of deep burns. The surface area of the bum wound and

Determination of heterocyclic aromatic amines in human urine by using hollow-fibre supported liquid membrane extraction and liquid chromatography-ultraviolet detection system.

A hollow-fibre supported liquid membrane (HF-SLM) extraction method has been developed for determination of 11 heterocyclic aromatic amines (HCAs) in human urine samples by using high performance liquid chromatography (HPLC) equipped with an ultraviolet (UV) absorbance detector. These compounds were extracted from an alkaline urine sample (donor phase) into the organic solvent residing in the pore

Pulses of somatostatin release are slightly delayed compared with insulin and antisynchronous to glucagon

It was early proposed that somatostatin-producing delta-cells in pancreatic islets have local inhibitory effects on the release of insulin and glucagon. Recent observations that pulses of insulin and glucagon are antisynchronous make it important to examine the temporal characteristics of glucose-induced somatostatin release. Analysis of 30 s fractions from the perfused rat pancreas indicated that

Basal-like phenotype is not associated with patient survival in estrogen-receptor-negative breast cancers

Introduction Basal-phenotype or basal-like breast cancers are characterized by basal epithelium cytokeratin (CK5/14/17) expression, negative estrogen receptor ( ER) status and distinct gene expression signature. We studied the clinical and biological features of the basal-phenotype tumors determined by immunohistochemistry (IHC) and cDNA microarrays especially within the ER-negative subgroup. Meth

A method for maintaining constant ethanol concentrations in cell culture media

The present study reports on the development of a model for maintaining constant ethanol concentrations over time in cell culture media. When neuroblastoma x glioma cells (NG 108-15) were grown in ethanol containing media under standard cultivation conditions in the incubator at 37 degrees C, a 90% evaporation was observed after 24 hr. To counteract evaporation, the cell culture dishes were placed

Supercritical fluid extraction of a lignocellulosic hydrolysate of spruce for detoxification and to facilitate analysis of inhibitors

This work describes a novel approach to detoxify lignocellulosic hydrolysates and facilitate the analysis of inhibitory compounds, namely supercritical fluid extraction (SFE). The efficiency of the fermentation of lignocellulosic dilute-acid hydrolysates depends upon the composition of the hydrolysate and the organism used. Furthermore, it has been shown that inhibitors in the hydrolysate reduce t

Oxygen modulates contractile responses to potassium and prostaglandin F2 alpha in human pial arteries

Oxygen may modulate cerebrovascular resistance, but its direct influence on human pial arteries is unknown. We have investigated the effects of varying oxygen tension (73, 30 and 8 kPa) in depolarized (potassium) and receptor stimulated (prostaglandin F2 alpha) isolated human pial arteries. Control responses were obtained at an oxygen tension of 30 kPa. Contractions induced by prostaglandin F2 alp

Variability and seasonality of North Atlantic climate during the early Holocene: evidence from Faroe Island lake sediments

Based on their position in relation to major ocean currents, palaeoclimatic archives in the Faroe Islands are expected to be sensitive recorders of variations in North Atlantic circulation. The multiproxy analysis ( magnetic susceptibility, total carbon, nitrogen and sulphur, biogenic silica, grains > 255 mu m) of a lacustrine record with both winter and summer climate indicators illustrates the v

Nitrous oxide reduces inspired oxygen fraction but does not compromise circulation and oxygenation during hemodilution in pigs

BACKGROUND: The use of nitrous oxide (N2O) during hemodilution has been questioned. Nitrous oxide reduces the inspired oxygen fraction (F1O2), depresses myocardial function and may reduce cardiac output (CO) and systemic oxygen delivery (DO2SY). The aim of this study was to evaluate the importance of the effects of nitrous oxide on systemic and myocardial circulation and oxygenation during extreme

Risk and prognosis of colorectal cancer following bacteraemia with Streptococcus bovis-Streptococcus equinus complex : A Swedish nationwide retrospective cohort study

There is a positive association between bacteraemia with Streptococcus bovis-Streptococcus equinus complex (SBSEC) and colorectal cancer (CRC). However, the relationship between the timing of SBSEC bacteraemia and CRC is not well-established. Associations with other gastrointestinal cancers have also been suggested. Using national registries, we retrospectively examined the incidence of CRC and ot

“Det är nog första arbetsplatsen där jag känner att här kan jag vara väldigt väldigt länge!” En kvalitativ intervjustudie med psykologer som arbetar med patienter utsatta för sexuella övergrepp

Studiens syfte var att genom tematisk analys undersöka hur psykologer upplever och påverkas av att behandla patienter utsatta för sexuella övergrepp, om och hur de främjar välmående genom egna copingstratgeier samt hur de bidrar till och påverkas av organisationen. Genom semi-strukturerade intervjuer med åtta psykologer verksamma på en mottagning tillägnad människor utsatta för sexuella övergrepp The purpose of this study was to, by using thematic analysis, investigate how psychologists experience and are affected by treating sexually assaulted individuals, if and how they use different coping strategies to maintain their own wellbeing and how they are affected by the organization. Semi-structured interviews were conducted with eight psychologists working in a clinic dedicated for patients

“Jag vill att dom visar att dom bryr sig!” En studie om gymnasieelevers perspektiv på elevhälsoteam

Studiens syfte var att undersöka och kartlägga gymnasieelevers syn på elevhälsan samt att konstruera ett mätinstrument för att genomföra undersökningen. Mot bakgrund av ökande psykisk ohälsa bland unga samt bristande nationell kartläggning av ungdomars perspektiv gällande elevhälsan var ansatsen med studien att lyfta gymnasieelevernas egna perspektiv i frågan. Studien genomfördes som en tvärsnittsThe aim of the current study was to explore high school students’ perspectives on the Swedish student health system (elevhälsan), as well as the construction of a survey instrument to implement the study. Due to the general increase in adolescent mental health issues alongside a lack of national research regarding adolescent views on elevhälsan, this cross-sectional explorative study seeked to amp

Professionellas perspektiv på psykisk ohälsa: attributionsskillnader mellan läkare, psykologer och kuratorer kopplat till stigma mot psykiatriska diagnoser

Vårdgivares förståelse av psykiatriska tillstånd har föreslagits hänga samman med deras stigma gentemot personer med sådana tillstånd. Detta stigma kan yttra sig genom förminskande beteenden, uteslutning från beslutsprocesser och försämrade terapeutiska relationer. Denna uppsats undersöker huruvida det finns en relation mellan psykiatrisk profession, attributionella ramverk och stigma gentemot perMental health professionals’ understanding of psychiatric conditions has been proposed to relate to their stigma toward individuals with such diagnoses. Such stigma may manifest through dismissive behavior, exclusion from decision-making and weakened therapeutic relationships. This thesis investigates whether psychiatric profession, attributional frameworks, and stigma toward ADHD, anxiety disorde

A Buffer-Refill Scheduling System for a Digital Small Scale Continuous Bioprocess

Efterfrågan på biologiska läkemedel blir allt större, i och med att det med tiden upptäckts fler användningsområden för till exempel antikroppar, enzymer och virus. Dessa har i många fall blivit standardläkemedel för att behandla till exempel diabetes, vissa neurologiska sjukdomar och HIV/AIDS. Biologiska läkemedel känneteckas av att produceras av celler som genetiskt har modifierats. Från dessa cThis thesis addresses a challenge in continuous high performance liquid chromatography (HPLC): ensuring reliable, timely supply of buffer solutions. As biopharmaceutical production increasingly moves toward continuous operation, buffer management becomes critical, since chromatography requires multiple buffer types with precise compositions for washing, elution, equilibration, and regeneration. In