Semenogelins I and II are the quantitatively dominating proteins in human semen. They comprise the major part of the sperm-entrapping gel formed at ejaculation, which subsequently liquefies due to proteolysis of the gel-forming proteins by prostate-specific antigen (PSA). The mechanism behind gel formation and its physiological significance is not known. We have studied phosphorylation and dephosp

Popular Abstract in Swedish Denna avhandling behandlar analys och förbättringar av en metod att mäta blödgenomströmning i vävnad med kontinuerlig ultraljudsdoppler. Tidigare har stora variationer i detekterat perfusionsvärde observerats som en effekt av speckle, eller våginterferens. Här presenteras en teoretisk modell som förklarar specklefenomenet i en sådan mätsituation. Modellen förutsäger deThis thesis has the main focus on ways to improve the blood perfusion estimate, as obtained from a continuous wave Doppler system. Earlier studies have shown large temporal variations in the detected perfusion estimate, due to speckle. Here, a theoretical model to predict frequency dependent characteristics of speckle in continuous wave ultrasound is presented. The model predicts the frequency shi

Whittaker was one of the leading ecologists of his generation, introducing several ideas to plant community ecology. One approach involved deriving environmental-correlation curves in attempts to determine how the abundance of individual species changed along environmental gradients. These curves have been used extensively in the ecological literature of the last 50 years. However, there has been

Two reactors, initially operated at 14 and 23 +/- 1 degrees C (RA and RB, respectively), were inoculated with a bacterial consortium enriched and acclimatized to the respective temperatures over 4 months. The biofilms, formed in the reactors, were studied using scanning electron microscopy, cultivation of the biofilm microflora, and physiological analysis of the isolates. Two bacteria able to mine

Women prostituting in Vilnius City, Lithuania, were studied with regard to their socioeconomic background, drug and alcohol abuse, conditions for prostituting and for the carrier rate of sexually transmitted infectious agents. The 73 women studied represented a group of low-socioeconomic prostitutes with a great age span, i.e. 14-52 years. Forty-five per cent had one or more children. Roughly one-

New radiative lifetime measurements based on time-resolved laser-induced fluorescence techniques are reported for 18 even-parity levels belonging to the 4f5d(2)6p and 4f(2)5d(2) configurations of Ce I and 6 even-parity levels belonging to the 5d(2)6s, 4f5d6p, and 4f6s6p configurations of Ce II. Free neutral and singly ionized cerium atoms were produced by laser ablation. The Ce I and Ce II levels

Framgångsrik klinisk forskning måste baseras på translationell forskning, där både kliniker och forskare ingår. Sådana team måste utgå från universiteten för att tillgodose kraven på kvalitet. Man bör även diskutera nationella fokusområden för den kliniska forskningen, så att den kompetens som finns i landet tillvaratas.

This thesis reports the work done in the development of a modified Lean Premix Prevaporised (LPP) burner for the use in Alstom Power Sweden’s industrial gas turbines. Incentive for the development of the modified burner have been the need to increase the flame stability over the operating range for the burner, especially for the liquid fuel but also the gaseous fuel operation. Foundation for modif

The effect of adding Thermomyces (formerly Humicola) lanuginosa lipase (TLL) to a monoolein (MO)/sodium oleate (NaO) aqueous cubic liquid crystalline phase has been studied. H-1-NMR, C-13-NMR, H-1-PGSE (Pulsed-magnetic field Gradient Spin-Echo) self-diffusion measurements, and Small Angle X-ray Diffraction were used to follow the degradation of the cubic phase. The reaction sequence in terms of ph

In principle, methods of testing the reliability and safety of constructions are designed with the aim of representing critical conditions for their use. Because of variations within technical systems, including the one for which a certain test was once developed, the validity of the method also varies. The adoption of a standardized test for different applications had to be based on the assumptio

A revised geometric representative model of the lower part of the colon, including the rectum, the urinary bladder and prostate, is proposed for use in the calculation of absorbed dose from injected radiopharmaceuticals. The lower segment of the sigmoid colon as described in the 1987 Oak Ridge National Laboratory mathematical phantoms does not accurately represent the combined urinary bladder/rect

Popular Abstract in Swedish Läkemedelsrelaterade problem hos äldre - Interventioner för att förbättra läkemedelsbehandlingen Läkare inom primärvården står för en stor del av den totala läkemedelsförskrivningen i Sverige och är en viktig målgrupp för läkemedelsindustrins information. Det har i flera uppmärksammade studier från Socialstyrelsen uppmärksammats att läkemedelsbehandlingen för patientIntroduction: Elderly people, in particular those residing in nursing homes, often use many drugs. In general elderly patients are at greater risk of experiencing drug-related problems (DRP), as they have multiple diseases, are using many drugs and have changed physiological status. Objectives: To describe the frequency of potential drug-related problems in the elderly and to evaluate different k

In the optimization of the ring-opening reaction of thiophene-1,1-dioxides, 3-bromo-2,5-dimethylthiophene-1,1-dioxide (1) and 2-(2-hydroxyethyl)piperidine (7) were chosen as model reagents. Solvent, temperature, molar ratio between amine and dioxide and the amount of solvent were variables included in the optimization. A central composite design was chosen for the investigation and a canonical ana