Several tumors secrete insulin-like growth factors (IGFs) for autocrine growth stimulation and protection from apoptosis. However, the mechanisms responsible for tumor growth in renal cell carcinoma (RCC) are unclear. In this study the biological role of exogenous IGFs in two malignant RCC cells (Caki-2 and SK-RC-52) were investigated in vitro, and compared to the breast cancer cell line MCF-7. IG

Ultraweak light emission (UWLE) was measured from leaves of various chillingsensitive (Lycopersicon esculentum, Cucumis sativus and Phaseolus vulgaris) and tolerant (Pisum sativum and Vicia faba) plants after exposure to low (47C) temperature in the light. UWLE increased upon chilling treatment combined with illumination with 200 mol m2 s1 PAR in all plants, by about 30 in tolerant and by more tha

Stoichiometric Al and W oxide films are prepared with high stability from the metallic state of the cathodes using conventional reactive DC magnetron sputtering on an industrial prototype scale. While for the Al, increased target power is a trivial way to increase growth rates, W oxide sputtering of optically functional films with sufficiently amorphous structure is severely limited by the effect

PURPOSE: The dissertation addresses the choice of mode of transport, and the selection process, for local travel to regional rail service, with special emphasis on the significance of the bicycle. APPROACH TO THE PROBLEM AND METHODOLOGY: Choice of mode can be viewed as a 2-stage selection process in which different alternatives are rejected at different points in time. First there is a sorting amo

RFSL Rådgivningen Skåne har på uppdrag av Länsstyrelsen i Skåne län kartlagt och uppmärksammat situationen för ungdomar i Skåne (13–25 år) som riskerar hedersrelaterat hot och våld på grund av sexuell läggning. Rapporten bygger dels på enkätsvar från polismyndigheten, grundskolor och gymnasieskolor, socialförvaltningar och ungdomsmottagningar, dels på berättelser från ungdomar. Genom kartläggninge

Popular Abstract in Swedish När en människa är död är det prästens uppgift i begravningsgudstjänsten att hålla griftetal. Hur präster i Svenska kyrkan och i Borgå stift löser denna uppgift är en viktig fråga med tanke på att begravningsgudstjänsten är det tillfälle då flest människor kommer i kontakt med kristen förkunnelse. Särskilt fokuserar studien på hur prästen som teolog och själavårdare lösThe aim of this thesis is, using a comparative approach, to examine the pastoral function of the funeral homily as a faith interpretation and a life interpretation in funeral services in the Church of Sweden and in the diocese of Porvoo in Finland. In the Church of Sweden, represented here by the diocese of Växjö, the diocese of Strängnäs, the diocese of Härnösand, and the Evangelical Lutheran Chu

We are interested in gaining more knowledge about the execution-time requirements of real-time control tasks, and this paper presents a system for gathering statistics of the execution times of real-time tasks. The system allows real-time code to be instrumented in order to gather, analyze, and present execution-time statistics. It has been used to instrument an existing hybrid controller to gathe

Release of cytotoxic granule proteins from activated eosinophil granules is considered to be a key pathogenic mechanism in eosinophilic diseases. Degenerated eosinophils and extracellular eosinophil granules have been repeatedly depicted. The present overview describes evidence that eosinophil lysis and distribution of free eosinophil granules (as opposed to 'classical degranulation') is an import

Review of a book on pietism in Sweden in the 1720s.

SAMMANFATTNING För att förstå beteendet hos puts på träullsskivor under upprepad upp fuktning och uttorkning utsattes remsor av putsade träullsskivor för uttorkning och upp fuktning under kontrollerade förhållanden. Remsornas deformationer, d.v.s. den axiella deformationen samt deformationer vinkelrätta mot remsornas längdaxel, bestämdes under pågående upp fuktning och uttorkning. Provningarna utf

A spectroscopic study of Sb-108 has been carried out as a part of a larger experiment where in total twenty-nine different residual nuclei were identified. This study gives the first information on excited levels in this nucleus. A low-lying two-quasi-particle multiplet together with some of the higher lying levels are discussed within the framework of the nuclear shell model. A rotational, strong

Morselized and impacted bone allografts are used successfully in hip and knee revisions, but experiments using bone chambers indicate that impaction actually can delay ingrowth of new bone into a graft. To understand the remodeling and incorporation process of morselized and impacted grafts, we studied the incorporation of morselized impacted autografts in lumbar fractures histologically. 4 patien

X-linked agammaglobulinemia (XLA) is an immunodeficiency caused by mutations in the gene coding for Bruton's agammaglobulinemia tyrosine kinase (Btk). A new edition of the database (BTKbase) of Btk mutations has been compiled containing 282 patient entries representing 175 unique molecular events.

Nutrient resorption prior to leaf senescence is an important mechanism of nutrient conservation in forest tree species. However, despite the abundance of literature on the subject, inter-specific comparison of common temperate tree species is complicated by both the variability of resorption efficiency, which is affected by many environmental factors, and methodological differences between the stu