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Event generators like pythia play an important role in physics studies at the Large Hadron Collider (LHC). While they make accurate predictions in the central region, i.e., at pseudorapidities η<5, a disagreement between pythia and measurements in the forward region η>7 has been observed. We introduce a dedicated forward physics tune for the pythia event generator to be used for forward physics st
Background: Cardiac arrhythmias are a common health problem. Both common and rare genetic risk factors exist for cardiac arrhythmias. Cardiac amyloidosis is a rare disease that may manifest various arrhythmias. Few large-scale whole exome sequencing studies elucidating the contribution of rare variations to arrhythmias have been published. Objective: To access gene collapsing analysis of rare vari
The evolution of gonochorism from hermaphroditism is linked with the formation of sex chromosomes, as well as the evolution of sex-biased and sex-specific gene expression to allow both sexes to reach their fitness optimum. There is evidence that sexual selection drives the evolution of male-biased gene expression in particular. However, previous research in this area in animals comes from either t
Background: Diverticulosis is a common condition and is thought to be increasing in the Western population. Several studies have attempted to estimate the prevalence of diverticulosis and it’s inflamed state, diverticulitis, with results varying depending on study population and methodology, The aim of this study was to investigate the prevalence of diverticulosis in patients undergoing colonoscop
Background: The cornerstone of a strong profession is the research that supports its knowledge base and practice. However, little is known about the range of international occupational therapy research. Objective: To explore the range and diversity of the international occupational therapy research from published peer reviewed literature in English during the year 2018. Methodology: Limited to 201
The regional loess stratigraphy in the Vojvodina region, in the southeastern Carpathian Basin, has often been successfully correlated to the global palaeoclimate. This is a quasi-continuous sedimentary record that provides detailed environmental reconstruction during the last four glacial/interglacial cycles. In this study, we present a standardized loess stratigraphy and illustrate how it correla
Background. To determine whether genetic risk factors for major depression (MD) and alcohol use disorder (AUD) interact with a potent stressor – death of spouse, parent, and sibling – in predicting episodes of, respectively, MD and AUD. Methods. MD and AUD registrations were assessed from national Swedish registries. In individuals born in Sweden 1960–1970, we identified 7586, 388 459, and 34 370
Municipal biowaste has a high potential for agricultural use. However, it requires an additional amendment to increase the nutritional content used during the composting process. The purpose of this study was to investigate the selection of compost-enhancing amendments from municipal biowaste using bibliometric and multicriteria analysis. The municipality of Yopal (Casanare, Colombia) was chosen a
Every person diagnosed with tuberculosis (TB) needs to initiate treatment. The World Health Organization estimated that 61% of people who developed TB in 2021 were included in a TB treatment registration system. Initial loss to follow-up (ILTFU) is the loss of persons to care between diagnosis and treatment initiation/registration. LINKEDin, a quasi-experimental study, evaluated the effect of 2 in
Biocompatible, tough, and photoluminescent hydrogels are highly desirable for biomedical applications in vivo. Herein, hybrid hydrogels prepared from silk fibroin (SF) and polyacrylic acid (PAA) and complexed with europium, named as SF-PAA-Eu3+ hydrogels, exhibit good comprehensive properties. Owing to the intensive molecular interactions among SF, PAA, and Eu3+, SF-PAA-Eu3+ hydrogels show a great
A handheld infrared camera was used to visualize heating and cooling of magnetic brakes in drop towers and roller coasters. The images also display the cooling effect of trees and the warming effect of clouds. This paper discusses what can be discerned from the photos with connections to data from data sheets, as well as from accelerometer and barometer sensors. The heating and cooling proces
The Western Gneiss Region (WGR) is a Precambrian basement domain in the Scandinavian Caledonides and one of the world's largest high- and ultrahigh-pressure terranes. The south–central WGR underwent regional eclogite facies metamorphism 415–400 Ma ago when Baltica subducted beneath Laurentia, during the Scandian orogeny. Eclogites in the WGR group into two traditional types: (1) Precambrian mafic
Aims/hypothesis: The aim of this study was to determine whether BMI in early childhood was affected by the COVID-19 pandemic and containment measures, and whether it was associated with the risk for islet autoimmunity. Methods: Between February 2018 and May 2023, data on BMI and islet autoimmunity were collected from 1050 children enrolled in the Primary Oral Insulin Trial, aged from 4.0 months to
Background: Childhood cancer survivors are at risk of subsequent gliomas and meningiomas, but the risks beyond age 40 years are uncertain. We quantified these risks in the largest ever cohort. Methods: Using data from 69,460 5-year childhood cancer survivors (diagnosed 1940–2008), across Europe, standardized incidence ratios (SIRs) and cumulative incidence were calculated. Results: In total, 279 g
Continuous task engagement generally leads to vigilance decrement and deteriorates task performance. However, how conflict effect is modulated by vigilance decrement has no consistent evidence, and little is known about the underlying neural mechanisms. Here we adopted an electroencephalogram dataset collected during a prolonged flanker task to examine the interactions between vigilance and congru
Importance: Patients with melanoma are selected for sentinel lymph node biopsy (SLNB) based on their risk of a positive SLN. To improve selection, the Memorial Sloan Kettering Cancer Center (MSKCC) and Melanoma Institute Australia (MIA) developed predictive models, but the utility of these models remains to be tested. Objective: To determine the clinical utility of the MIA and MSKCC models. Design
The automation of map labeling is an ongoing research challenge. Currently, the map labeling algorithms are based on rules defined by experts for optimizing the placement of the text labels on maps. In this paper, we investigate the feasibility of using well-labeled map samples as a source of knowledge for automating the labeling process. The basic idea is to train deep learning models, specifical
Stochastic reconstruction is widely employed for effective and flexible imitation of Gas Diffusion Layers (GDLs), e.g., to facilitate the study of their properties. However, the reconstruction often overlooks crucial factors such as fiber curvature, fiber stack arrangement, and fiber anisotropy. Consequently, the impact of these structural characteristics remains poorly understood. In this study,
The bacterial ribosome is an essential drug target as many clinically important antibiotics bind and inhibit its functional centers. The catalytic peptidyl transferase center (PTC) is targeted by the broadest array of inhibitors belonging to several chemical classes. One of the most abundant and clinically prevalent resistance mechanisms to PTC-acting drugs in Gram-positive bacteria is C8-methylat
In this paper, we aggregate, analyze, and exemplify several metrics for the information value. The metrics vary by absolute value, normalizations, or full probabilistic quantification. The normalization of the information value encompasses the division by (1) the expected and maximized utility of the base scenario (usually without additional information), (2) by the system performance, or (3) by t
