Gliomas are among the most aggressive malignant tumors and the most refractory to therapy, in part due to the propensity for malignant cells to disseminate diffusely throughout the brain. Here, we have used 27 K cDNA microarrays to investigate global gene expression changes between normal brain and high-grade glioma (glioblastoma multiforme) to try and better understand gliomagenesis and to identi

Byggd miljö knyts med tiden ofta till olika mer eller mindre specifika betydelser. Vill vi förändra staden måste vi också förhålla oss till de livsmönster och det bruk som uppstått inom ramen för den gamla bebyggelsen, oavsett om vi vill bygga nytt vid sidan av eller förändra det gamla i grunden. Denna artikel avser belysa något kring hur vi kan undersöka en sådan lokal etablering av betydelser oc

Treatment with adrenocorticotrophic hormone (ACTH) has a well-documented cholesterol-lowering effect. Increased uptake of low-density lipoprotein (LDL) by HepG2 cells in response to incubation with ACTH has been demonstrated but the precise cholesterol-lowering mechanism has resisted elucidation. Since apolipoproteins are important determinants of lipoprotein metabolism, we sought to extend the kn

Expression of genes for respiratory chain dehydrogenases was investigated in potato (Solanum tuberosum L. cv. Desiree) leaves. The recently characterized nda1 and ndb1 genes, homologues to genes encoding the non-proton pumping respiratory chain NADH-dehydrogenases of Escherichia coli and yeast, were compared to genes encoding catalytic subunits of the proton-pumping NADH dehydrogenase (complex I).

We describe the epidemiology of all distal radial fractures in young adults (men 20-59 years, women 20-49 years) in Lund (1992-95) and Malmo (1994-95), Sweden. During the study period, there were 341 patients with 346 fractures in the two cities, found through the Hospital Register of Diagnoses in Lund and the register of the Radiology Department in Malmo. More than half of the fractures were disl

Abstract is not available

Three previously unknown high-energy gamma-ray transitions between 4.2 and 5.4 MeV were identified in the T-z=-1/2 nucleus Fe-51 following the fusion-evaporation reaction S-32(Si-28, 2alpha1n)Fe-51. These transitions represent decays of core excited states. The gamma rays were detected in the Ge detector array Gammasphere combined with the neutron detector system Neutron Shell and the charged-part

Background: The bactericidal effect of some antibiotic and antineoplastic agents commonly used in clinical practice was investigated to analyse whether the combinations act synergistically, have indifferent or antagonistic antibacterial effects compared to the effect of the antibiotics alone. Methods: The rate of killing of meropenem, ceftazidime and tobramycin was studied against six different st

Abstract is not available

UV-B treatment of thylakoid membranes or fractions derived from them accelerates the first rise (Fo---Fi phase) of variable fluorescence and slows down the second (Fi---Fm) rise. This can be observed for all membrane fractions but to different extents. The grana fraction is affected more by the UV-B treatment than are the intact thylakoids and the stroma lamella fraction. An exogenous electron acc

A phase of approximate composition SbVO4 has been reported in the literature as a key component in new catalysts for the ammoxidation of propane to acrylonitrile. Sb0.92V0.92O4 was prepared by heating equimolar amounts of Sb2O3 and V2O5 in air at 1073 K for 2 hr. The chemical composition was determined by thermogravimetry and energy dispersive X-ray microanalysis. The crystal structure at 293 K wa

A combination of x-ray absorption and resonant photoemission (RPE) spectroscopy has been used to study the electronic structure of the one-dimensional conjugated polymer poly (para-phenylenevinylene) in nonordered (as prepared) thin films. The dispersion of RPE features for the decay to localized and delocalized bands are qualitatively different. A theory for band dispersion of RPE in polymers is

This study describes the integrated sympathetic/metabolic control of capillary pressure (Pc) and filtration in cat skeletal muscle as studied during graded exercise and superimposed graded (2, 6 and 16 Hz) vasoconstrictor nerve excitation. The applied technique permitted simultaneous analysis of the underlying changes of resistance in the whole vascular bed (RT) and in its large-bore arterial resi