PDE5 inhibitors was reported to play a protective role in both regulating lipid metabolism and reducing heart failure (HF). This study aimed to clarify the effectiveness of PDE5 inhibitors against hyperlipidemia-related HF by combining evidence from population-based study and animal models. The nationwide cohort study found that post-diagnostic use of PDE5 inhibitors was associated with a signific

Om Giorgiana Masi och Benno Ohnesorg

Testing autonomous driving systems for safety and reliability is essential, yet complex. A primary challenge is identifying relevant test scenarios, especially the critical ones that may expose hazards or harm to autonomous vehicles and other road users. Although numerous approaches and tools for critical scenario identification are proposed, the industry practices for selection, implementation, a

BACKGROUND: To strengthen palliative care for children in the Nordic countries, an updated status of current needs, resources, clinical services, education, and research is necessary to align and consolidate future research. A Nordic research collaboration initiative for children with palliative care needs was assembled in 2023. Building on this initiative, this paper presents an overview of pedia

The novel Coronavirus disease 2019 (COVID-19) presents a major threat to public health but can be prevented by safe and effective COVID-19 vaccines. Vaccine acceptance among healthcare workers (HCWs) is essential to promote uptake. This study, aimed to determine the COVID-19 vaccination uptake and hesitancy and its associated factors among HCWs in Tanzania. We employed a convergent-parallel mixed-

This cross-sectional study investigates the shifts in anxiety levels among Swedish employees throughout the Covid-19 pandemic, with data gathered in 2016, 2018, and 2020. Work-related anxiety was assessed through two metrics: General Work Anxiety (WA) and Work Performance Anxiety (WPA). Overall, there was a decline in both average WA and WPA over the five-year period. However, this trend did not a

The lasso is a popular method to induce shrinkage and sparsity in the solution vector (coefficients) of regression problems, particularly when there are many predictors relative to the number of observations. Solving the lasso in this high-dimensional setting can, however, be computationally demanding. Fortunately, this demand can be alleviated via the use of screening rules that discard predictor

Amyloid proteins are species whose aggregation has been associated with various neurodegenerative diseases. While intrinsically disordered in their monomeric form, they tend to aggregate into highly ordered β-sheet rich fibrils. Nevertheless, many studies indicate that intermediate species known as amyloid oligomers, which are linked to neurotoxicity, may be the connection between amyloid proteins

Xanthoria ectaneoides, usually recognised by its secondary sublobules, is circumscribed in a strict sense using spore size and a molecular phylogeny based on ITS-sequences. The spe- cies, earlier considered a synonym of X. aureola, forms a subclade with X. coomae and the new species X. pylyporlykii, described here, whereas X. aureola is positioned in the Xanthoria calcicola subclade. The new speci

Recognizing individual differences is essential for creating inclusive and effective educational settings that support all children's learning and school success and that are considerate of their varying needs. The primary aim of this work was to help uncover some of the influencing factors and underlying dynamics that affect children’s individual educational attainment. Through brain imaging and

In this paper, a wideband circularly polarized antenna is designed for integration into the glass roof of a modern car for GNSS positioning applications. Characteristic mode analysis is used to obtain more physical insight into the problem and hence satisfy the polarization and bandwidth requirements. The antenna has a low profile and uses a single coplanar waveguide feed to cover all GNSS bands.