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Do the CNS monoaminergic (MA) systems regulate thyroid hormone metabolism in humans? In 23 unmedicated, male, violent offenders without signs of thyroid disease, we found positive correlations between the catecholaminergic CSF metabolites HVA and MHPG and the peripheral T3/T4 ratio (rho=0.55, p=0.010 and 0.51, p=0.018), indicating that increased activity in the brain MA systems, especially the dop

The desert gerbil Psammomys obesus, an established model of type 2 diabetes (M), has previously been shown to lack pancreatic and duodenal homeobox gene 1 (Pdx-1) expression. Pdx-1 deficiency leads to pancreas agenesis in both mice and humans. We have therefore further examined the pancreas of P. obesus during embryonic development. Using Pdx-1 antisera raised against evolutionary conserved epitop

Abstract is not available

The objectives of this paper are to identify in-vehicle systems for speed management that have been or are being developed, and to suggest recommendations for the implementation of systems that will effectively influence driving speeds and thereby significantly increase safety. The best safety effect is expected from an "intelligent" gas pedal, more specifically the automatic speed limiter. Howeve

OBJECTIVE: To determine costs of illness for adult diabetes mellitus (DM), including complications caused by DM. DESIGN: A population-based multicentre cross- sectional study including an interview and a physical examination of patients identified as having DM. The patients' medical records were analysed regarding diagnoses and complications attributable to DM. SETTING: Eight health care centres o

A recently constructed long-path enclosive flow cooling apparatus is employed to obtain the Fourier transform gas-phase infrared absorption spectrum of natural isotopic trans-1,2-dichloroethylene with a resolution of 0.00190 cm(-1) in the 800-1000 cm(-1) spectral region. The rotational structure of the out-of-plane CH flapping fundamental has been analyzed for the isotopic analogues Cl-35(2) and (

Z(SPA-1) is an engineered protein that binds to its parent, the three-helix-bundle Z domain of staphylococcal protein A. Uncomplexed Z(SPA-1) shows a reduced helix content and a melting behavior that is less cooperative, compared with the wild-type Z domain. Here we show that the difference in folding behavior between these two sequences can be partly understood in terms of an off-lattice model wi

An analytical method for the analysis of 3-aminopropionamide (3-APA) based on derivatization with dansyl chloride and liquid chromatography/fluorescence detection was developed. We have analysed 3-APA formation in raw potatoes, grown and stored under different condition, green and roasted coffee beans and in freeze dried mixtures of asparagine with sucrose and glucose in molar ratio of 1:0.5, 1: 1

We have performed a joint theoretical and experimental study to investigate the terahertz radiation from Bloch oscillations in a GaAs/Al0.3Ga0.7As superlattice under the condition that there is no Zener tunneling. The total radiation intensity has been calculated with a semiclassical approach in the low field regime where the Wannier-Stark ladder (WSL) cannot be resolved, and with an exact numeric

The findings from the Prostate Cancer Prevention Trial (PCPT) and how they relate to the management of prostate disease were reviewed by leading European urologists during a meeting held in December 2005. The consensus opinions that were reached were endorsed by the European Association of Urology and are documented here. The key points of the consensus are as follows: (1) The overall results from

Adaptive step size control is difficult to combine with geometric numerical integration. As classical step size control is based on "past" information only, time symmetry is destroyed and with it the qualitative properties of the method. In this paper we develop completely explicit, reversible, symmetry-preserving, adaptive step size selection algorithms for geometric numerical integrators such as

The study focused on the performance of a group of Swedish children with language impairment (LI) on a referential communication task as a step in the investigation of their pragmatic skills. The task entailed choosing a single card from a selection of 16 depicting a face and describing it well enough for the opponent in order for him/her to pick the correct one from his/her identical array of car

It is argued that the assumption that the standard model particles live on a finite brane in the ADD model does in itself imply a finite propagator for virtual Kaluza-Klein mode exchange. The part of the propagator relevant for large distance scattering is cut-off-independent for scattering at distances large compared to the brane width. The matrix element corresponding to this part can also, at l

Gasification is an important option for the swift implementation of biomass combined heat and power. processes in the Danish energy supply system. Tar-water produced by the gas-cleaning system of gasifiers may contain substances toxic to nitrifying bacteria. As the gasification plants are small and often located in the catchment area of small wastewater treatment plants, discharge of the tar-water

Objective To describe changes between 1992 and 2003 in age, sex, factors at resuscitation and survival among patients suffering from out-of-hospital cardiac arrest in Sweden. Methods This was a prospective observational study including various ambulance organizations in Sweden. Patients suffering from out-of-hospital cardiac arrest between 1992 and 2003 included in the Swedish Cardiac Arrest Regis