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One of the major quantitative trait loci (QTLs) associated with arthritis in crosses between B10.RIII and RIIIS/J mice is the Cia5 on chromosome 3. Early in the congenic mapping process it was clear that the locus was complex, consisting of several subloci with small effects. Therefore, we developed two novel strategies to dissect a QTL: the partial advanced intercross (PAI) strategy, with which w

It has been shown that users of a digital system perceive a more ‘masculine-sounding’ female voice as more persuasive and intelligent than a corresponding but more ‘feminine-sounding’ female voice. Our study explores whether a parallel pattern of affectively colored evaluations can be elicited when femininity and masculinity are manipulated via visual cues instead of via voice. 80 participants enc

For the first time, Pulsed Field Gradient-Nuclear Magnetic Resonance, a powerful noninvasive tool for studying the dynamics and structure of complex-gels, has been used to measure diffusion of probe molecules in aqueous solutions/gels of noncommercial purified pig gastric mucin (PGM), in a concentration range up to 5 wt%. Complementary data were obtained from rheology measurements. The combination

Shells of the common intertidal gastropod Littorina littorea both of recent and mid-Holocene origin were analysed along their growth spirals for seasonally induced variations in stable oxygen and carbon isotope compositions. The subfossil specimens are from the Stone Age kitchen midden in Ertebolle, northern Denmark, dated between 5970 +/- 95 and 5070 +/- 90 BP The recent specimens were collected

Today, sheet-metal-forming simulation is a powerful technique for predicting the formability of automotive parts. Compared with traditional methods such as the use of try-out tools, sheet-metal-forming simulation enables a significant increase in the number of tool designs that can be tested before hard tools are manufactured. Another advantage of sheet-metal-forming simulation is the possibility

This paper presents a new fast approach to improving stability in polynomial equation solving. Gröbner basis techniques for equation solving have been applied successfully to several geometric computer vision problems. However, in many cases these methods are plagued by numerical problems. An interesting approach to stabilising the computations is to study basis selection for the quotient space C[

Absorption microspectrophotometry has been shown to be of considerable help to probe crystalline proteins containing chromophores, metal centres, or coloured substrates/co-factors. Absorption spectra contribute to the proper interpretation of crystallographic structures, especially when transient intermediate states are studied. Here it is shown that fluorescence microspectrophotometry might also

The aim of the present study was to determine to what extent adult rats can produce new contracting bladder muscle and to see if such newly formed bladder tissue possesses characteristic mechanical properties or whether the ability to recover mechanically is so pronounced that the prehistory of the bladder is unimportant. Subtotal cystectomy was performed in adult female rats, leading to a pronoun

The development of tolerant microorganisms is needed for the efficient fermentation of inhibitory lignocellulose hydrolysates. In the current work, the fermentation performance of six selected strains of Saccharomyces cerevisiae in dilute-acid spruce hydrolysate was compared using two different modes of fermentation; either single pulse addition of hydrolysate to exponentially growing cells or con

The spectrum of six times ionized sulphur, S VII, has been investigated in the wavelength region 200-4000 Angstrom by means of the beam-foil and laser-produced plasma techniques. The analysis comprises 219 lines of which 105 are newly identified. The present work establishes 123 2s(2)2p(5)nl energy levels of which 66 are new. The level energies are determined with an internal consistency of better

Dedicated clinics have been established for the early diagnosis and treatment of women at risk for inherited breast cancer, but the effects of such interventions are currently unproven. This second report on prospectively diagnosed inherited breast cancer from the European collaborating centres supports the previous conclusions and adds information on genetic heterogeneity and the effect of oophor

For the past decade innovativeness, as opposed to innovation, has received considerable attention in the academic literature as well as the corporate arena because it is considered to promote a competitive advantage. This study examines the link between innovativeness and performance of SMEs in the Swiss watch industry, in terms of customer orientation, competition orientation and inter-functional

In order to evaluate if incorrect staging of Wilms tumor resulted in inadequate treatment a retrospective reevaluation was performed. During 1982-1990 153 patients were treated in Sweden. The review revealed that 6 cases were not Wilms tumor and 25 cases had incomplete information. The remaining material consisted of 122 cases. The survey of the charges revealed that the initial distribution was s

The present study was designed to demonstrate a hypothesis that some G-protein coupled receptors are up-regulated and a dysfunction of endothelium occurs in hypertension. The arteries from hypertensive patients and spontaneously hypertensive rats (SHR) were tested. An in vitro myograph system was used to obtain concentration-contraction curves mediated by endothelin ETA, endothelin ETB, 5-hydroxyt

Four different dispersing agents for solubilisation of single walled carbon nanotubes (SWNT) are here compared. Dispersing agents used here can be divided into the group of organic solvents (dimethylformamide and cyclohexanone) and charged polymers (Nafion and chitosan). Charged polymers are more efficient dispersing agents allowing quicker dispersion of nanotubes compared to solvents. Moreover ch

The changes in interface structure and chemical composition of a 99.995% pure nickel/yttria-stabilised zirconia (YSZ) interface were examined after heat treatment at 1000 °C in 97% H2/3% H2O with and without polarisation. Impedance spectroscopy was used for electrochemical characterisation. The results were compared to earlier investigations of a less pure nickel/YSZ interface. The pure interface