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Neuroblastoma is a childhood malignancy originating from cells of the sympathetic nervous system, exhibiting a marked diversity in outcome, with spontaneous regression at one end of the spectrum and severe disease and death at the other end. Features associated with frequent recurrence, a poor prognosis, and high tumor stage are loss of heterozygosity in the distal region of chromosome 1p and ampl
Superficial blood perfusion mas monitored using laser-Doppler perfusion imaging in connection with a phase LII clinical trial comparing photodynamic therapy, utilizing topically applied aminoleuvlinic acid, with cryotherapy of basal cell, carcinomas. A total of 526 images mere recorded before and immediately after the treatment and during the follow-up period. Before treatment, the lesions exhibit
The aim of the study was to evaluate an experimental approach based on a fluid percussion rat trauma model in combination with the microdialysis technique for the analysis of cerebral interstitial biochemical alterations following head trauma, and to test the hypothesis that the previously observed acute accumulation of lactate and increase in the lactate pyruvate ratio may persist for several day
A total of 47 firms joined the Swedish EKO-Energi programme between 1994 and 1997. This was a public voluntary programme devoted to promoting the environmental vanguard, while disregarding the rearguard. The programme offered free energy audits and the promotion of a label, in return for implementation of energy management. Audits covered some 5% of industrial energy consumption. The most clearly
Measurements of Z gamma* production are presented using data collected by the DELPHI detector at centre-of-mass energies ranging from 183 to 209 GeV, corresponding to an integrated luminosity of about 667 pb(-1). The measurements cover a wide range of the possible final state four-fermion configurations: hadronic and leptonic (e(+) e(-) q (q) over bar, mu(+) mu(-) q (q) over bar ,q (q) over barv (
Where am I and what am I seeing? This is a classical vision problem and this paper presents a solution based on efficient use of a combination of 2D and 3D features. Given a model of a scene, the objective is to find the relative camera location of a new input image. Unlike traditional hypothesize-and-test methods that try to estimate the unknown camera position based on 3D model features only, or
Purpose: To characterize the clinical phenotype, with emphasis on electrophysiology, of two children with suspected Bothnia dystrophy. Methods: Two unrelated affected patients, 10 and 11 years old, were studied. Ophthalmological examination included testing of visual acuity, fundus inspection and fundus photography, kinetic perimetry, full-field electroretinogram (ERG), and multifocal ERG. The pre
Lipid droplets are cytoplasmic organelles which serve as storage sites for neutral lipids. Adipose differentiation-related protein (ADRP) is intrinsically associated with the surface of lipid droplets and is believed to play a major role in the maintenance of lipid stores in non-adipocytes. ADRP abundance is intimately linked to the amount of lipid found within cells and agents which increase the
PURPOSE: A spin-echo diffusion-sensitized pulse sequence using high gradients (23 mT/m) is introduced. MATERIAL AND METHODS: In order to minimize motion artefacts, velocity-compensating gradients, ECG-triggering and post-processing with phase correction and raw data averaging using navigator echoes was performed. The in vitro ratio of diffusion coefficients for water and acetone was determined and
In this report, which is the first in a series of three reports, an existing computer control system in a heavy-duty truck from Volvo Truck Corporation has been investigated. The aim of the report and of the DICOSMOS case study at Volvo Technological Development is to design and study a future computer control system for a truck and semi-trailer vehicle combination. The functionality in focus is v
The theoretical background and research evidence supporting two alternative scenarios – worsening health and improving health at increasing life expectancy is analyzed. It is shown that the prevailing “longer life – worse health” theory is based on the logic that due to the reduced birth-rate and increased proportion of older citizens the process of population aging is taking place, leading to an
Specific hydroxy groups of the terminal disaccharide unit of globotriaosyl ceramide (Gb(3)Cer) were identified from binding studies with deoxyGb(3)Cer and verotoxins (VTs) [Nyholm, Magnusson, Zheng, Norel, Birmington-Boyd and Lingwood (1996) Chem. Biol. 3, 263-275]. Four such hydroxy groups (2", 4", 6" and 6') were each substituted with an amino group and the corresponding deoxyamino globotrioses
Popular Abstract in Swedish Avhandlingens huvudfråga är hur språket används i skolämnet naturkunskap i två mångkulturella gymnasieklassrum. Språket ses som vår viktigaste resurs för utveckling och lärande i olika skolämnen. Att elever får rikliga tillfällen att lära sig hantera ämnesrelevant språk blir enligt ett sådant synsätt avgörande för vilket språk de utvecklar och vad de lär sig. SpråkutvecThe purpose of the thesis is to investigate how language is used in the school subject Natural Science in two multi-cultural upper seconday classrooms. Previous research points to the fact that second language students are not successful in their school work. The reason usually given is the students' inadequate knowledge of their second language. Today's curricular directives of the Swedish school
