Effective treatment of experimental acute otitis media by application of volatile fluids into the ear canal
Essential oils are volatile and can have good antimicrobial activity. We compared the effects of oil of basil ( Ocimum basilicum) and essential oil components ( thymol, carvacrol, and salicylaldehyde) to those of a placebo when placed in the ear canal of rats with experimental acute otitis media caused by pneumococci or Haemophilus influenzae. Progress was monitored by otomicroscopic examination a