A novel approach for functionalising and separating Tröger's Base Analogues
Tröger’s Base (TB) is a bicyclic compound containing a methanodiazocine group between two aromatic rings. The methylene bridge forces the molecule to have a bent formation; thus, the aromatic rings are close to 90 degrees relative to each other, resulting in a rigid concave aromatic cavity. These unique properties make TB a great candidate as a molecular cleft compound and a good structure as a mo
