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RNA modifying enzymes play a pivotal role in reshaping gene expression programs in response to diverse intracellular and extracellular cues, thereby maintaining cellular homeostasis. When dysregulated, these enzymes are increasingly implicated in the onset and progression of various diseases. While traditionally recognised for their catalytic functions, mounting evidence suggests that many RNA mod

Pixel sensors in 3D technology equip the outer ends of the staves of the Insertable B Layer (IBL), the innermost layer of the ATLAS Pixel Detector, which was installed before the start of LHC Run 2 in 2015. 3D pixel sensors are expected to exhibit more tolerance to radiation damage and are the technology of choice for the innermost layer in the ATLAS tracker upgrade for the HL-LHC programme. While

The human brain is a complex and finely tuned organ, constantly monitored and maintained by its resident immune cells.Among these, microglia are the primary regulators of the brain immune environment under physiological conditions, and monocyte-derived macrophages contribute mainly to pathological states such as ischemic stroke and neuronopathic Gaucher’s disease (GD). These two diseases, although

This thesis, comprising four research papers, contributes to the field of systematic and computer-aided analyses and design of first-order methods. The first two papers focus on developing new methodologies, while the remaining two apply these techniques to refine complexity and convergence results, as well as to design new methods. A central theme of the work is the use of Lyapunov-type analyses,

This co-authored article develops Border Work (BW) as a methodological approach which is under explored in socio-legal scholar-activism, through analysing two distinct examples. While both examples depart from feminist methodology, the differences are stark: Noor, excluded from democratic processes, faced deportation risks, while we, with institutional support, engaged in public mobilizations withThis co-authored article develops Border Work (BW) as a methodological approach which is under explored in socio-legal scholar-activism, through analysing two distinct examples. While both examples depart from feminist methodology, the differences are stark: Noor, excluded from democratic processes, faced deportation risks, while we, with institutional support, engaged in public mobilizations with

The combined use of the inverse kinematics technique and the advanced detection setup R3B (Reactions with Relativistic Radioactive Beams) at GSI/FAIR provides unique opportunities to study the fission process. This approach provides access to the complete isotopic identification of the two fission fragments, the precise determination of their velocities and the measurement of the neutrons and gamm

We measured the angular distributions for the 12C(7Be,3He)16O transfer reaction at 35 MeV leading to several excited states of 16O. The angular distribution of the ground state of 16O was measured for the first time in this reaction. The corresponding Asymptotic Normalization Coefficients (ANC) of all the observed states were determined. The ANC of ground state, 6.92 MeV (2+) and 7.12 MeV (1−) sub

In recent years, the empirical literature on cross-national unions—marriages between migrants and members of the majority population—has experienced a shift in focus, with an increasing number of studies examining assortative mating patterns within these unions. This shift marks a significant development, indicating that the classic assimilation theory is no longer considered the sole explanation

In memoriam of Charles T. Tart

Algoritmiska rekommendationer har blivit allt mer förekommande i vardagen. Från filmer, musik och potentiella partners till söta katter och roliga danser – sociala medieplattformar utvecklar kraftfulla algoritmer för att förutsäga vad användarna kommer tycka om och behöva. Algoritmiska rekommendationer föreslår dock inte samma innehåll till alla användare, utan anpassar sina rekommendationer dynamAlgorithmic recommendations have become ubiquitous in everyday life. From films, music, and potential partners to cute cats and silly dances, social media platforms develop powerful algorithms to predict what users might like and need. However, algorithmic recommendations do not suggest the same content to all users but instead adapt their recommendations dynamically through endless feedback loops

A Review of Defining and Supporting the Scholarship of Teaching and Learning (SoTL): A Sector-Wide Study by Joëlle Fanghanel, Jane Pritchard, Jacqueline Potter, and Gina Wisker

Thermal stability of mechanically alloyed nanocrystalline AlxCoCrFeNi (x = 0, 0.3, 0.6, 1 mol) high entropy alloys (HEAs) has been investigated for the low and intermediate temperature range of 673–1073 K. Single phase FCC structure is observed in the as milled CoCrFeNi. A mixture of FCC and BCC phases is exhibited by × = 0.3, 0.6 and 1, alloys where the volume fraction of BCC increases with incre

The microwave absorption property of epoxy resins is generally poor, which can be improved by introducing fillers such as carbon nanotubes and metal oxide nanoparticles (NPs) having good microwave absorption characteristics. In this paper, the microwave absorption properties of epoxy-ZnO nanocomposites have been studied. The ZnO NPs were synthesised using the sol–gel technique and characterised fo

This article introduces the pattern theory of immersivity (PTI), a practice-led theoretical framework stemming from the hypothesis that a reorientation of the understanding of immersive art is needed, away from technological sophistication or sensory excess and toward the psychological mechanisms underlying imaginative engagement, regardless of artform or combination of media. The theory posits th

Syftet med avhandlingen är att bidra med kunskap om hur förskoleklasselevers förmåga att bestämma och flexibelt hantera antal och tal utvecklas över tid med och utan deltagande i specifikt utformade undervisningsinsatser, med fokus på lågpresterande elever. I avhandlingen undersöks särskilt hur denna förmåga kan stödjas med utgångspunkt i konceptuell subitisering, vilket definieras som en förmåga

This paper presents a measurement of the production cross-section of a Z boson in association with b- or c-jets, in proton–proton collisions at s=13 TeV with the ATLAS experiment at the Large Hadron Collider using data corresponding to an integrated luminosity of 140 fb-1. Inclusive and differential cross-sections are measured for events containing a Z boson decaying into electrons or muons and pr

A search is presented for the pair production of heavy vectorlike quarks (VLQs) that each decay into a W boson and a light quark. This study focuses on events where one W boson decays into leptons and the other into hadrons. The search analyzed 140 fb−1 of pp collision data with pffiffi s ¼ 13 TeV, recorded by the ATLAS detector from 2015 to 2018 during run 2 of the Large Hadron Collider. The fina

Background: Childhood constipation is increasingly common, yet its prevalence is uncertain. This study examines comprehensive national data for trends in medically treated childhood constipation over a period of 18 years.Methods: Included were all Swedish children, 0-14 years, 2006-2023, and all prescriptions for constipation, using the national Swedish Prescribed Drug register. The primary outcomBackgroundChildhood constipation is increasingly common, yet its prevalence is uncertain. This study examines comprehensive national data for trends in medically treated childhood constipation over a period of 18 years.MethodsIncluded were all Swedish children, 0–14 years, 2006–2023, and all prescriptions for constipation, using the national Swedish Prescribed Drug register. The primary outcome wa

Objectives: Aidarken is a region with mercury production from cinnabar and, to a lesser extent, from mercury-antimony-fluorite and waste recycling. Recent smelting emissions of elemental Hg vapour are low; however, combined with past pollution legacies, anaemia and iodine deficiency, the health effects for vulnerable populations are still possible. The study aimed to evaluate metal(loid)s status i

Jordbruket är grundläggande för livsmedelssäkerhet och försörjning på landsbygden, men sektorn står inför varaktiga hållbarhetsutmaningar. Moderna produktionssystem har ökat avkastningen men också bidragit till markförstöring, förlust av biologisk mångfald och utsläpp av växthusgaser. Denna avhandling undersöker hur jordbrukspolitiska styrmedel kan utformas för att förbättra både den ekonomiska efAgriculture is fundamental to food security and rural livelihoods, but the sector faces persistent sustainability challenges. Modern production systems have increased yields but also contributed to soil degradation, biodiversity loss, and greenhouse gas emissions. This thesis examines how agricultural policy instruments can be designed to improve the economic efficiency and environmental effective