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The aim of the present paper is to discuss strategies to minimize contrast medium (CM) doses in patients at risk of CM-induced nephropathy (CIN) after computed tomographic angiography (CTA), and percutaneous catheter angiography (PCA) and vascular interventions (PVI). In general a gram-iodine (g-I)/eGFR ratio >= 1.0 appears to be a significant and independent predictor of CIN in CTA and coronary i
Migration of Earth-sized planets in 3D radiative discs
Plasma Volume Expansion with 5% Albumin Compared to Ringer's Acetate during Normal and Increased Microvascular Permeability in the Rat.
It is believed that the effectiveness of colloids as plasma volume expanders is dependent on the endothelial permeability for macromolecules. The objective of this study was to test the hypothesis that the plasma volume expanding effect of 5% albumin relative to that of a crystalloid solution is reduced if microvascular permeability is increased.
Modeling freedom from progression for standard-risk medulloblastoma : A mathematical tumor control model with multiple modes of failure
Purpose As pediatric medulloblastoma (MB) is a relatively rare disease, it is important to extract the maximum information from trials and cohort studies. Here, a framework was developed for modeling tumor control with multiple modes of failure and time-to-progression for standard-risk MB, using published pattern of failure data. Methods and Materials Outcome data for standard-risk MB published af
Knee malalignment is associated with an increased risk for incident and enlarging bone marrow lesions in the more loaded compartments: the MOST study
Objective: To examine the relationship of knee malalignment with occurrence of incident and enlarging bone marrow lesions (BMLs) and regression of BMLs. Methods: Subjects from the Multicenter Osteoarthritis Study aged 50-79 years with or at high risk of knee osteoarthritis were studied. Full-limb radiographs were taken at baseline and hip-knee-ankle mechanical axis was measured. Baseline and 30-mo
Older people's views of quality of care: a randomised controlled study of continuum of care.
To analyse frail older people's views of quality of care when receiving a comprehensive continuum of care intervention, compared with those of people receiving the usual care (control group). The intervention included early geriatric assessment, case management, interprofessional collaboration, support for relatives and organising of care-planning meetings in older people's own homes.
Osteoarthritis: Replacing the meniscus to prevent knee OA-fact or fiction?
Fracture analysis of perpendicular to grain loaded dowel-type connections using a 3D cohesive zone model
The strength and fracture behavior of dowel-type connections with stiff dowels loaded perpendicular to grain was studied by nonlinear 3D finite element (FE)-analysis. A cohesive zone model was used to model the perpendicular to grain fracture of the wood, i.e., failure by wood splitting along the grain. The influence of load eccentricity and dowel-to-loaded-edge distance was studied for a plate ty
Friendship network characteristics and psychological well-being in late adolescence: Exploring differences by gender and gender composition
Aims: The aim of the present study was to examine the association between friendship networks and psychological well-being among 19-year-olds. Methods: The data used was a random sample of Swedish individuals born in 1990 who answered a questionnaire in 2009–2010. Friendship networks were considered in terms of three measures of emotional support. Six statements about the individual’s emotional st
Introducing an equal rights framework for older persons in residential care
This article reconceptualizes residential care for older persons by introducing a framework developed from a rights-based principle of disability policies, the normalization principle. This principle is part of the social model and states that society should make available for people who have impairments living conditions that are as close as possible to those of “others.” Using the framework on t
Minimally modified LDL upregulates endothelin type B receptors in rat basilar artery
Minimally modified low density lipoprotein (mmLDL) is a well-known risk factor for cerebral vascular diseases and upregulation of endothelin type B (ETB) receptors plays key roles in the pathogenesis. The present study was designed to examine if mmLDL upregulated endothelin ETB receptors in basilar artery and its possible intracellular signaling molecular mechanisms. Rat basilar arteries were cult
Diffusion Tensor Imaging of Normal-Appearing White Matter as Biomarker for Radiation-Induced Late Delayed Cognitive Decline
Purpose: To determine whether early assessment of cerebral white matter degradation can predict late delayed cognitive decline after radiotherapy (RT). Methods and Materials: Ten patients undergoing conformal fractionated brain RT participated in a prospective diffusion tensor magnetic resonance imaging study. Magnetic resonance imaging studies were acquired before RT, at 3 and 6 weeks during RT,
Researching farmer behaviour in climate change adaptation and sustainable agriculture: Lessons learned from five case studies
Understanding farmer behaviour is needed for local agricultural systems to produce food sustainably while facing multiple pressures. We synthesize existing literature to identify three fundamental questions that correspond to three distinct areas of knowledge necessary to understand farmer behaviour: 1) decision-making model; 2) cross-scale and cross-level pressures; and 3) temporal dynamics. We u
Multiplicity dependence of two-particle azimuthal correlations in pp collisions at the LHC
We present the measurements of particle pair yields per trigger particle obtained from di-hadron azimuthal correlations in pp collisions at root s = 0.9, 2.76, and 7TeV recorded with the ALICE detector. The yields are studied as a function of the charged particle multiplicity. Taken together with the single particle yields the pair yields provide information about parton fragmentation at low trans
Natural Pseudoguaianolides Prepared from Damsin
Damsin (1) is a pseudoguaianolide sesquiterpene possessing potent biological activities, reported as a metabolite of several medicinal plants belonging to the genus Ambrosia together with related compounds. Starting from 1, which can be isolated in good amounts from Ambrosia arborescens, the five natural pseudoguaianolides ambrosin (2), isodamsin (3), 3 alpha-hydroxydamsin (4), 3 alpha-acetoxydams
Lactate formation in Caldicellulosiruptor saccharolyticus is regulated by the energy carriers pyrophosphate and ATP
Caldicellulosiruptor saccharolyticus displays superior H(2) yields on a wide range of carbon sources provided that lactate formation is avoided. Nevertheless, a low lactate flux is initiated as the growth rate declined in the transition to the stationary phase, which coincides with a drastic decrease in the glucose consumption and acetate production fluxes. In addition, the decrease in growth rate
Low-temperature cathodoluminescence studies of GaAs nanowires in the SEM
We present data from cathodoluminescence (CL) studies of nanowires (NWs) grown from size-selected gold particles using metal-organic chemical vapour deposition. The NWs in this study all have a GaAs core and are surrounded by a shell of either AlGaAs or GaInP. The spatially and spectrally resolved CL studies were performed in a scanning electron microscope, in a temperature range of 4–300 K. The N
Modelling DIC and DOC transport from the Baltic Sea catchment
The Utility of Digital Linear Tomosynthesis Imaging of Total Hip Joint Arthroplasty with Suspicion of Loosening: A Prospective Study in 40 Patients
Aim. The clinical utility of digital linear tomosynthesis in musculoskeletal applications has been validated in only a few reports. Technical performance and utility in hip prosthesis imaging have been discussed in technical reports, but no clinical evaluation has been reported. The purpose of the current study was to assess the added clinical utility of digital linear tomosynthesis compared to ra
