The role of inorganic pyrophosphate (PPi) as an energy carrier in the central metabolism of the extremely thermophilic bacterium Caldicellulosiruptor saccharolyticus was investigated. In agreement with its annotated genome sequence, cell extracts were shown to exhibit PPi-dependent phosphofructokinase and pyruvate phosphate dikinase activity. In addition, membrane-bound pyrophosphatase activity wa

Diabetic patients have a much more widespread and aggressive form of atherosclerosis and therefore, higher risk for myocardial infarction, peripheral vascular disease and stroke, but the molecular mechanisms leading to accelerated damage are still unclear. Recently, we showed that hyperglycemia activates the transcription factor NFAT in the arterial wall, inducing the expression of the pro-atheros

En av de ständigt aktuella frågorna i den kommunala ekonomiska debatten är den kommunala resultatutvecklingen. Går den att påverka eller är kommuners situation allt för styrd av externa faktorer? I denna studie, som finns att hämta på www.rka.nu, närmar vi oss dessa frågor med två övergripande frågor; Vad gör kommuner för att åstadkomma en förbättrad resultatutveckling? Vilka effekter har vidtag

Background & Aims: Assess the prevalence of peri-transplant heart failure and its potential relation to post-transplant morbidity and mortality. Methods: A retrospective study was performed on 234 consecutive cirrhotic patients undergoing liver transplantation in a single European center from 1999 to 2007 (mean age 52, 30% women, 36% with alcoholic liver disease, 24% with viral hepatitis, 18%

We study connections between topological dynamical systems and associated algebras of crossed product type. We derive equivalences between structural properties of a crossed product and dynamical properties of the associated system and furthermore derive qualitative results concerning the crossed product that are true regardless of the corresponding dynamical system. The systems principally invest

The purpose of this study was to evaluate the coherence between three different methods assessing the power driven from a counter movement jump (CMJ); the Powertimer 300-series contact mat (C-mat), the MuscleLab 4010 infrared mat (IR-mat) and the MuscleLab 4010 linear encoder (M-encoder), and to evaluate the test-retest reliability of the M-encoder.

Aims To explore the association of HbA1c and educational level with risk of cardiovascular events and mortality in patients with Type2 diabetes. Methods A cohort of 32871 patients with Type2 diabetes aged 35years and older identified by extracting data from electronic patient records for all patients who had a diagnosis of Type2 diabetes and had glucose-lowering agents prescribed between 1999 and

The incidence of asthma and allergy has increased throughout the developed world over the past decades. During the same period of time, the use of industrial chemicals such as phthalates, commonly used as plasticizers in polyvinylchloride (PVC) flooring material, has increased. The aim of this study was to investigate whether PVC flooring in the home of children in the age of 1-5years is associate

Head Computed Tomography (CT) imaging is still a commonly obtained diagnostic test for patients with minor head injury despite availability of clinical decision rules to guide imaging use and recommendations to reduce radiation exposure resulting from unnecessary imaging. This prospective multi-center observational study of 251 patients with suspected mild to moderate traumatic brain injury (TBI)

Recension av Barbro Eberan, Brunt arv. Skuldfrågan efter Tysklands återförening 1990.

Increased levels of cardio-enriched microRNAs (miRNAs) have been described in patients with myocardial infarction (MI). We wanted to evaluate the diagnostic and prognostic potential of cardio-enriched miRNAs in patients presenting with a suspected acute coronary syndrome (ACS).

Popular Abstract in Arabic Vårt immunförsvar är fantastiskt. Dagligen exponeras vi för bakterier, virus och andra sjukdomsalstrande mikroorganismer och i allra flesta fall besegrar vårt immunförsvar detta hot utan problem. I sällsynta fall uppstår det dock en situation då bakterier lyckas undvika vårt initiala immunförsvar, sprids i kroppen och orsakar blodförgiftning (sepsis). Vid detta tillståndSepsis is a heterogeneous, dynamic, and complex syndrome caused by interaction between the host and the invading pathogen. It is associated with an overwhelmingly dysregulated immune response, and also immunosuppression. In spite of our improved understanding of the underlying molecular pathology, sepsis still remains a common cause of morbidity and mortality worldwide. This is reflected in the un

The EULAR Sjögren's syndrome (SS) disease activity index (ESSDAI) is a systemic disease activity index that was designed to measure disease activity in patients with primary SS. With the growing use of the ESSDAI, some domains appear to be more challenging to rate than others. The ESSDAI is now in use as a gold standard to measure disease activity in clinical studies, and as an outcome measure, ev

From the mid-1990s onwards, the humanities and social sciences have devoted a great deal of attention to the operations of the affects, and there has been much talk about "the affective turn". This article begins by looking at the impact of that phenomenon on scholarly and critical work on T. S. Eliot, a milder impact than one might have expected. It then goes on to investigate the interplay of em

The aim of this present study was to examine duration of breastfeeding in relation to the risk of different subgroups of breast cancer. A prospective cohort, The Malmö Diet and Cancer study, including 14092 parous women, were followed during a mean of 10.2 years and a total of 424 incident breast cancers were diagnosed.

The aim of this thesis was to test a tool for assessing insomnia symptoms in elderly persons and to investigate late-life insomnia in terms of associated factors and evidence of non-pharmacological interventions in healthcare settings. Data were collected by means of a systematic literature search (Study I), questionnaires (Studies II-III), interviews and observations (Study IV). The results from

Taxonomic treatments recognize three varieties of Cercis canadensis: with variety canadensis, widespread throughout the eastern United States, and varieties texensis and mexicana, found east and west of the Pecos River in Texas, respectively. The distribution of Cercis continues southward into northeastern Mexico, but complex variation in leaf shape has confounded straightforward application of va

This article explores the core propositions articulated by several public actors in the so-called Bandera debate, i.e., discussions about the usable past and legacy of the wartime Ukrainian nationalist insurgency and its central symbolic figure, Stepan Bandera. In Western Ukraine, popular historical imagery as well as intellectual polemics about “Ukrainization” of World War II challenged both the