Popular Abstract in English Living organisms are composed of mainly carbohydrate, protein and lipid molecules. Protein molecules are responsible for many biological functions in cells. In order to fulfill their various biological roles, these chain-like molecules must fold into precise three-dimensional shapes. The knowledge of accurate molecular structures is a prerequisite for rational drug desiProtein molecules are responsible for many biological functions in cells. In order to fulfill their various biological roles, these chain-like molecules must fold into precise three-dimensional shapes. The knowledge of accurate molecular structures is a prerequisite for rational drug design and for structure based functional studies. Getting structural information of proteins can be a very difficu

The typical catalyst layers (CLs) in proton exchange membrane fuel cells (PEMFCs) are fabricated as random heterogeneous composites to meet the multifunctional requirements of transport phenomena and electrochemical activity. The employment of Pt nano-particles, carbonaceous substrates and Nafion ionomers in CLs allows effective diffusion of hydrogen and oxygen, transport and phase change of water

Test planning for core-based 3D stacked ICs with trough-silicon vias (3D TSV-SIC) is different from test planning for non-stacked ICs as the same test schedule cannot be applied both at wafer sort and package test. In this paper, we assume a test flow where each chip is tested individually at wafer sort and jointly at package test. We define cost functions and test planning optimization algorithms

Many proteins in bovine milk exhibit specific biological activity in addition to their established nutritional value as source of protein. Examples of such bioactive proteins are extracellular glutathione peroxidase, lactoferrin and immunoglobulins. Extracellular glutathione peroxidase (eGSHPx) fulfils an antioxidative function, immunoglobulins are antimicrobial, and it has been suggested that lac

This is a detailed guide on the principles of cognitive therapy as they are applied to problems of emotion (anxiety, sadness, anger), skill (assertiveness, problem-solving), and general confidence in children and adolescents. The title is slightly misleading in the sense that there is little in the book that specifically relates to how this treatment would be applied in school settings by school p

It is well known that dielectrics with the reconstruction of zone structure (Pb1-xSnxTe, for example) have two-dimensional layers with a specific electron properties. A corresponding relativistic model has been discussed, in particular, by B.A. Volkov and O.A. Pankratov (1985). The general nature of the effect under consideration can be demonstrated by in a simple model setting, and the aim here i

Despite the considerable import of both response probability and response time for testing models of choice there is a dearth of chronometric studies of time- and space-order effects in discrimination of paired visual stimuli. In this study, systematic asymmetries in discriminating the brightness of paired visual stimuli are examined by way of binary response probability scaled in terms of log-odd

The presented thesis work is concerned with the study of molecular dynamics using liquid nuclear magnetic resonance (NMR) spectroscopy. Spin relaxation dispersion experiments in the rotating frame (R1ρ) are employed to provide a detailed, atomic-resolution view of protein dynamics. Comprehensive investigations of 15N backbone and 13C methyl side-chain conformational exchange in the FK506 binding p

In Statoil, understanding and managing risk is today considered a core value. This principle has been duly integrated in the organization, and is inscribed in steering documents as well as in a booklet handed out to all employees, describing core values, corporate governance, the operating model and corporate policies. The company has developed a sophisticated approach to ERM that centers on the p

A critical assessment of a widely applied approach for the prediction of temperature-insensitive absorption lines is presented. This approach was found to suffer from significant shortcomings.

In this paper the problems of organization and representation of concept knowledge are addressed from an autonomous agent perspective. The first part of the paper discusses the question of why an autonomous agent needs concepts at all and what other uses it can make of them. After the necessary and/or desirable functions of concepts have been identified, previous attempts to represent concepts are