Synthesis of 3-azido-2,4,6-tri-O-(4-methoxybenzyl)-3-deoxy-galactopyranoside
Galectin-3 is a protein that is involved in many physiological processes such as metastasis, T-cell regulation etc. which makes it a good drug target for the medicinal chemist. In a paper made by Doak ete al (2015) macrocyclization emerged as an interesting strategy for new drug design as macrocycles remained orally active in chemical space previously thought of as “unsuitable” as per the classica