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The ECM exerts great effects on cells, and changed composition may therefore have profound impact. Small leucine-rich proteoglycans, e.g. fibromodulin, are essential in collagen assembly. Our aim was to investigate the role of fibromodulin in healthy and fibrotic lung parenchyma, theorizing that fibromodulin-deficient animals would be protected against fibrosis. Repeated subcutaneous bleomycin-inj

It can be said that literary texts do not have any obligation to reality, and that literature destabilises our relations to the everyday use of words and to established perspectives. Literature stands in relation to something that cannot be explained or conceptualised, and in this respect it is close to religion. I argue that many of these characteristics of literature are also features of philoso

Objective. The current study used islet amyloid polypeptide (IAPP) knockout mice (KO mice) to investigate the physiological role of IAPP in the regulation of food intake (FI). Material and methods. FI and body weight were measured in KO and wild-type (WT) mice for 27 weeks. In an additional short-term experiment, IAPP (25 pmol . kg(-1)min(-1)) was infused subcutaneously for 3 days in KO and WT mic

Iterated filtering is an algorithm for estimating parameters in partially observed Markov process (POMP) models. The real-world performance of the algorithm depends on several tuning parameters. We propose a simple method for optimizing the parameter governing the joint dynamics of the hidden parameter process (called the Sigma matrix). The tuning is implemented using a fixed-lag sequential Monte

This paper presents a decoder for multi-carrier modulated signals employing Faster-than-Nyquist (FTN) signaling. FTN signaling is a method of improving bandwidth efficiency at the expense of higher processing complexity in the transceiver. The decoder can switch between orthogonal and FTN signaling modes and exploits channel properties to improve bandwidth efficiency. The decoder is fabricated in

The legitimacy of the judiciary hinges on the presumption that truth can be found through the judicial process. Even though a distinction can be made between "truth" in a legal sense and "real truth", the legal truth can only be justified by its anchorage in "real truth". During the last few decades, the previosly all-powerful assumption of the objective nature of reality and knowledge has been ch

The dynamic phase diagram of triethylene glycol dodecyl ether (C12E3) in D2O was determined for 40, 50, and 60 wt % of surfactant. The shear flow effect on the nonionic lamellar phase was investigated as a function of temperature and concentration. The transition from planar lamellae (L-alpha)-to-multilamellar vesicles (MLVs) was characterized by means of rheology, rheo-small-angle neutron and lig

Targino, A. C., Krecl, P., Johansson, C., Swietlicki, E., Massling, A., Coraiola, G. C. & Lihavainen, H. 2013: Deterioration of air quality across Sweden due to transboundary agricultural burning emissions. Boreal Env. Res. 18: 19-36. We analyzed measurements of aerosol and trace-gas concentrations from sites across Sweden before and during a series of agricultural wildland fires in eastern Eu

OBJECTIVETo study the association between dietary flavonoid and lignan intakes, and the risk of development of type 2 diabetes among European populations.RESEARCH DESIGN AND METHODSThe European Prospective Investigation into Cancer and Nutrition-InterAct case-cohort study included 12,403 incident type 2 diabetes cases and a stratified subcohort of 16,154 participants from among 340,234 participant

Transactional sex is associated with the HIV epidemic among young people in Uganda. Few quantitative studies based on nationally representative survey data explored the relationship between sexual behaviors, HIV infection, and transactional sex.

The essential spectrum of the singular matrix differential operator of mixed order determined by the operator matrix [GRAPHICS] is studied. Investigation of the essential spectrum of the corresponding self-adjoint operator is continued but; now without assuming that the quasi-regularity conditions are satisfied. New conditions that guarantee that the operator is semi-bounded from below are derived

The global supplier network is becoming an increasingly important asset for many firms. If successfully managed, supplier relationships may support the firm's strategic orientation and become a sustainable advantage on the global market. A key question is thus how the firm can develop and maintain such relationships. The market-driving strategy has recently been advanced as a more pro-active type

Searches for pair-produced scalar leptoquarks are performed using 20 fb[Formula: see text] of proton-proton collision data provided by the LHC and recorded by the ATLAS detector at [Formula: see text] TeV. Events with two electrons (muons) and two or more jets in the final state are used to search for first (second)-generation leptoquarks. The results from two previously published ATLAS analyses a

We investigate the optical properties of periodic composites containing metamaterial inclusions in a normal material matrix. We consider the case when these inclusions have sharp corners and, following Hetherington and Thorpe, use analytic results to argue that it is then possible to deduce the shape of the corner (its included angle) by measurements of the absorptance of such composites when the

The skin constitutes an effective barrier mediating protection against environmental danger and foreign substances. At the surface of the skin, the residential microorganisms grow as small colonies and consist of various non-pathogenic bacteria, fungi and viruses. However, the cutis is also exposed to pathogenic microorganisms, and to combat this threat the residential cells of the epidermis have

In this paper we propose a scheme for test planning and test access mechanism (TAM) design for stacked integrated circuits (SICs) that are designed in a core-based manner. Our scheme minimizes the test cost, which is given as the weighted sum of the test time and the TAM width. The test cost is evaluated for a test flow that consists of a wafer sort test of each individual chip and a package test