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Monitoring internal erosion in embankment dams using 3D Electrical Resistivity Tomography: Älvkarleby test embankment dam
One major risk threatening embankment dam integrity is internal erosion of the core. Internal erosion progresses inside the dam but it is difficult to detect with conventional methods. Electrical Resistivity Tomography (ERT) is a potential-based method that can sense the interior of the dam, and this study aims to evaluate the capability of ERT as a complementary monitoring technique for discoveri
How proven is a 'proven intervention'? Ethics of placebo controls in light of conditional approval programs
This article discusses the difficulties of establishing whether there exists a proven therapeutic intervention when regenerative experimental treatments are made accessible to patients under conditional approval programs (outside clinical trials). Conditional approvals are often made on the basis of less robust efficacy evidence than otherwise required for the registration of new treatments. Lower
Gustavson syndrome is caused by an in-frame deletion in RBMX associated with potentially disturbed SH3 domain interactions
RNA binding motif protein X‐linked (RBMX) encodes the heterogeneous nuclear ribonucleoprotein G (hnRNP G) that regulates splicing, sister chromatid cohesion and genome stability. RBMX knock down experiments in various model organisms highlight the gene’s importance for brain development. Deletion of the RGG/RG motif in hnRNP G has previously been associated with Shashi syndrome, however involvemen
Public History in Action : Past and Present Practices of Making History Public
The Case Against an Israeli-Saudi Deal : America Shouldn’t Push for a Hollow Accord
Nonsinusoidal current-phase relations in semiconductor-superconductor- ferromagnetic insulator devices
Coherent tunneling processes of multiple Cooper pairs across a Josephson junction give rise to high harmonics in the current phase relation. In this work, we propose and study Josephson junctions based on semiconductor-superconductor-ferromagnetic insulator heterostructures to engineer nonsinusoidal current-phase relations. The gate-tunability of the charge carriers' density in the semiconductor,
Exploring a New Application of Construct Specification Equations (CSEs) and Entropy : A Pilot Study with Balance Measurements
Both construct specification equations (CSEs) and entropy can be used to provide a specific, causal, and rigorously mathematical conceptualization of item attributes in order to provide fit-for-purpose measurements of person abilities. This has been previously demonstrated for memory measurements. It can also be reasonably expected to be applicable to other kinds of measures of human abilities and
The Pitfalls of a Popular Concept : Co-Production in Times of Individualization, Marketization, and De-Politicization
Co-production between public administrators and citizens has attracted renewed interest in recent years. Co-production is predominantly perceived as something desirable and is claimed to improve service efficiency and outcome and user satisfaction, at the same time as addressing democratic ideals. Drawing from interviews with public administrators and patients in a Swedish healthcare context, this
Chemometrics in Protein Formulation : Stability Governed by Repulsion and Protein Unfolding
Therapeutic proteins can be challenging to develop due to their complexity and the requirement of an acceptable formulation to ensure patient safety and efficacy. To date, there is no universal formulation development strategy that can identify optimal formulation conditions for all types of proteins in a fast and reliable manner. In this work, high-throughput characterization, employing a toolbox
(2963) Proposal to reject the name Rubus pseudoidaeus (Rosaceae)
Germline variants of the genes involved in NF-kB activation are associated with the risk of COPD and lung cancer development
Chronic obstructive pulmonary disease (COPD) and lung cancer (LC) are closely related diseases associated with smoking history and dysregulated immune response. However, not all smokers develop the disease, indicating that genetic susceptibility could be important. Therefore, the aim of this study was to search for the potential overlapping genetic biomarkers, with a focus on single nucleotide pol
Optimization of Chemical Bonding through Defect Formation and Ordering-The Case of Mg7Pt4Ge4
The new phase Mg7Pt4Ge4 (Mg8□1Pt4Ge4; □ = vacancy) was prepared by reacting a mixture of the corresponding elements at high temperatures. According to single crystal X-ray diffraction data, it adopts a defect variant of the lighter analogue Mg2PtSi (Mg8Pt4Si4), reported in the Li2CuAs structure. An ordering of the Mg vacancies results in a stoichiometric phase, Mg7Pt4Ge4. However, the high content
Oceans : The new economic frontier?
Since the Rio+20 gathering in 2012, and under the banner of blue growth, heads of state, corporations, investors and environmental NGOs have been debating the oceans’ role in solving everything from world food security, to provisioning of energy and natural resources, to mitigating the impacts of climate change and ensuring improved medical care. For the ocean and its resources to play this role,
FFPP
The extension of the project “FFPP” inspired by the lighthouses and lighthouse keepers of Porto Pi and Portocolom in Mallorca.
Restoring areas after a radioactive fallout : A multidisciplinary study on decontamination
Land remediation is an important part of restoration measures after a radioactive fallout containing long-lived fission products such as 137Cs. In this multidisciplinary study, we focused on three main issues related to remediation of contaminated urban areas. First, we assessed how much decontamination contributes to reducing resident radiation exposure and how much this reduction depends on the
Beckers Award recipient exhibition, Färgfabriken : Färg Fabriken, Porto Pi (FFPP)
Size Matters: Differences in friendship group size from a personality and cultural perspective
Alpha to Omega
Husk and Seed
Exhibition at Societe för konst:scenkonst och kultur i Västerås