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Migration patterns and phenotypic differentiation of long-term expanded human neural progenitor cells after transplantation into the adult rat brain.

We have examined long-term growth-factor expanded human neural progenitors following transplantation into the adult rat brain. Cells, obtained from the forebrain of a 9-week old fetus, propagated in the presence of epidermal growth factor, basic fibroblast growth factor, and leukemia inhibitory factor were transplanted into the striatum, subventricular zone (SVZ), and hippocampus. At 14 weeks, imp

Det extraordinäras lockelse : Luffarturistens bilder och upplevelser

Popular Abstract in Swedish ”Luffarturismen” har blivit en populär form av resande. Många svenskar för under en tid - ibland flera månader eller år - en vagabonderande tillvaro på platser långt hemifrån. Resan blir en parentes i vardagen - en extraordinär sfär fylld av förväntningar på äventyret och den äkta upplevelsen. Vad har resenären för bild av det ”Långtbortistan” hon lockas av, och hur skThis dissertation, The Attraction of the Extraordinary - Images and Experiences Among Backpacker Tourists, is a study based on informal interviews with predominantly Swedish independent travellers, as well as observations and documentary analysis of the backpacker subculture. Backpacking is a type of tourism which has been gradually institutionalized. Through the institutionalization of the backpa

Identification of Isomeric States "South" of Pb-208 via Projectile Fragmentation

Relativistic fragmentation of Pb-208 has been used to produce excited states in neutron-rich nuclei with N approximate to 126. Spectroscopic information for a range of nuclei has been obtained through observing delayed gamma-ray emissions from isomeric states. Preliminary results for Pt-203,Pt-204 nuclei are presented. For the first time, excited states have been observed in Pt-203 and Pt-204. The

Carbohydrate groups of alpha1-microglobulin are important for secretion and tissue localization but not for immunological properties

The role of the carbohydrates for the structure and functions of the plasma and tissue protein alpha1-microglobulin (alpha1m) was investigated by deletion of the sites for N-glycosylation by site-directed mutagenesis (N17,96-->Q). The mutated cDNA was expressed in a baculovirus-insect cell system resulting in a nonglycosylated protein. The biochemical properties of N17,96Q-alpha1m were compared to

Urinary S100B protein concentrations are increased in intrauterine growth- retarded Newborns

BACKGROUND. Intrauterine growth retardation is one of the major causes of perinatal mortality and morbidity. To date, there are no reliable methods to detect brain damage in these patients. METHODS. We conducted a case-control study in tertiary NICUs from December 2001 to December 2003 with 42 intrauterine growth retardation infants and 84 controls. Routine laboratory variables, neurologic outcome

The human V-preB promoter is a target for coordinated activation by early B cell factor and E47.

The development of mature B lymphoid cells involves a highly orchestrated regulation of stage- and lineage-specific genes. In this study, we report an analysis of the human surrogate L chain VpreB promoter. The promoter has an overall homology of 56% to the mouse counterpart and displays a preB cell-restricted activity in transient transfections in cell lines. The promoter harbors three independen

Search for effective therapy against glioblastoma multiforme - Clinical immunisation with autologous glioma cells transduced with the human interferon-gamma gene

Based upon earlier experimental work by our group, we have started a human immuno-gene therapy study. The goal is to study the effects of immunisation with autologous tumour cells expressing gene sequences for human interferon-gamma For more than two decades we have sought for efficient treatment against malignant gliomas. Our most successful treatment in the animal models is immuno-gene therapy w

Respiratory symptoms and lung function in young adults with severe alpha(1)-antitrypsin deficiency (PiZZ).

BACKGROUND: Neonatal screening for alpha(1)-antitrypsin (AAT) deficiency was undertaken in Sweden between 1972 and 1974 when 129 infants with severe AAT deficiency (phenotype PiZ) were identified. The cohort has been followed up prospectively. METHODS: 124 PiZ subjects, still alive and still living in Sweden, were invited to a follow up examination at about 22 years of age. The check up included a

Plasma carotenoids in relation to food consumption in Granada (southern Spain) and Malmo (southern Sweden)

We conducted a cross-sectional pilot study on healthy pre-menopausal women (aged 45-50 years) living in Granada, in the south of Spain (n = 39) and Malmo, in the south of Sweden (n = 38) in order to compare their plasma carotenoid levels and to investigate the relationship between the differences in food consumption. Plasma concentrations of six carotenoids were measured using high performance liq

The use of single walled carbon nanotubes dispersed in a chitosan matrix for preparation of a galactose biosensor

Chitosan was chosen as a natural polymer for dispersion of single walled carbon nanotubes (SWNT) based on its ability to efficiently solubilize SWNTs to form a stable dispersion. Moreover, chitosan films deposited on a surface of a glassy carbon (GC) electrode are mechanically stable. Further stabilisation of the chitosan film containing SWNT (CHIT-SWNT) was done by chemical crosslinking with glut

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Abstract in German Es wurden die Ergebnisse von 116 Blutalkoholbestimmungen in Fällen klinisch behandelter und sämtlich überlebter Alkoholvergiftungen von Kindern bis zu 14 Jahren ausgewertet. In 84 Fällen war die nähere Untersuchung der Anamnese, der klinischen Symptomatik und des Verlaufes möglich. Jungen waren deutlich häufiger betroffen als Mädchen (Verhältnis 4:1). Das durchschnittliche AlterThis study is based on 116 blood alcohol estimations of intoxicated children up to 14 years of age; all these children recovered after several hours of clinical treatment. In 84 cases the data about the anamnesis, the neurological symptoms, and the clinical course could be evaluated in detail. The average age of children was 10 years; most of them (60%) were 11--14 years old. Sex distribution: 4 m