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Development and Application of Enzyme- and Antibody-based Assays with Emphasis on Selectivity, Sensitivity and Stability

Popular Abstract in Swedish Utveckling och tillämpning av enzym- och antikroppsbaserade analysmetoder med tyngpunkt på selektivitet, sensitivitet och stabilitet Molekylär igenkänning är fundamental för funktioner ho's biologiska system. Biologisk aktiva substanser med specifik igenkänning för en målmolekyl tillämpa's mer och mer inom olika användningsområden, där de efterliknar dera's naturliga fThis thesis presents the development, optimisation, and various applications of enzyme-based biosensors and immunoassays, mainly with relevance to environmental analysis. the thesis discusses problems and possible solutions associated with selectivity, sensitivity and robustness of such bioassays with emphasis on various immunoasssay configurations for determination of surfactants, phenols, or dru

Does competition with monetary prize improve student learning? An exploratory study on extrinsic motivation

Student motivation is a key to effective deep learning. This paper aims at exploring competition as key motivating element in teaching of SCM at master level. The paper reports on our experiences from introducing monetary prices for student group works as a measure to increase extrinsic student motivation. A main question is to investigate how monetary prizes and other rewards mechanisms affect th

Effects of Sound Type on Recreating the Trajectory of a Moving Source

The ABBI (Audio Bracelet for Blind Interaction) device is designed for visually impaired and blind children to wear on the wrist and produce sound based on the movement of the arm through space. The primary func- tion is to inform a child (or adult) about his/her own movements to aid spatial cognition rehabilitation. How- ever, the device could also be worn by friends and family and be used to inf

SOX11 in Mantle Cell Lymphoma - Novel Tools for Diagnostic, Prognostic and Functional Investigations

Popular Abstract in Swedish Forskning kring biomarkörer har revolutionerat cancersjukvården. Några av de mest kända exemplen är PSA-testet som kan användas för att identifiera patienter med ökad risk för prostata cancer eller de nya antikroppsbehandlingarna, t.ex mot HER2 (trastuzumab/Hercepin) eller CD20 (rituximab/Rituxan), som gör att man nu ofta kan förlänga eller bota patienter som tidigare hThe goal of biomarker discovery is to identify disease defining molecules, which could be used to improve early detection and/or to predict survival and response to treatment. This thesis is about the transcription factor SOX11, a protein discovered in the context of mantle cell lymphoma in 2008, which shows great potential to be used as a clinical relevant biomarker. The aim of this thesis is to

Accuracy of finite element predictions in sideways load configurations for the proximal human femur

Abstract in UndeterminedSubject-specific finite element models have been used to predict stress-state and fracture risk in individual patients. While many studies analysed quasi-axial loading configurations, only few works simulated sideways load configurations, such as those arising in a fall. The majority among these latter directly predicted bone strength, without assessing elastic strain predi