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The role of the intermediate filament protein desmin in hypertrophy of smooth muscle was examined in desmin deficient mice (Des -/-). A partial obstruction of the urethra was created and after 9-19 days bladder weight increased about 3-fold in both Des -/- and wild type (Des +/+) animals. Bladder growth was associated with synthesis of actin and myosin. In the hypertrophic Des +/+ bladder the rela

The purpose of this study was to develop a computer-assisted diagnosis (CAD) system based on image-processing techniques and artificial neural networks for the interpretation of bone scans performed to determine the presence or absence of metastases. METHODS: A training group of 810 consecutive patients who had undergone bone scintigraphy due to suspected metastatic disease were included in the st

The aim of this study was to investigate walking and health among woman age 75 yr or older, in the associations between the highest step up performed without support by an individual and balance, walking, and health among women age 75+. Records of the highest step, balance, walking, and health were made for 307 women age 75-93 yr living in the community. Eighty percent managed to climb steps highe

Background: Under inflammatory conditions, T cell-dependent (TD) protein antigens induce proinflammatory T-and B-cell responses. In contrast, tolerance induction by TD antigens without costimulation triggers the development of regulatory T cells. Under both conditions, IgG antibodies are generated, but whether they have different immunoregulatory functions remains elusive. Objective: It was shown

Syftet med denna studie är att analysera hur de involverade aktörerna upplever, definierar och tolkar ett behandlingsprojekt, som involverade samhällsomhändertagna ungdomar. Projektet involverade olika myndigheter vars representanter skulle innefatta en vårdkedja och benämndes Motverka Våld och Gäng (MVG-projektet). I projektet var också ett antal samordnare anställda. Utöver redovisningen av våraThis report concerns a large evaluation of a project concerning Swedish juvenile care. We analyse how professionals, youngsters and parents perceived and interpreted the three-year project which involved different authorities whose representatives should form a care-giving chain. The project also employed a number of coordinators. Beyond accounting for the results from just over one houndred inter

Pain upon negative pressure wound therapy (NPWT) dressing removal has been reported and is believed to be associ- ated with the observation that granulation tissue grows into foam. Wound tissue damage upon removal of the foam may cause the reported pain. Calcitonin gene-related peptide (CGRP) and substance P are neuropeptides that cause inflam- mation and signal pain and are known to be released w

This report summarises our efforts in deriving, characterising and banking of 20 different human embryonic stem cell lines. We have derived a large number of human embryonic stem cell lines between 2001 and 2005. One of these cell lines was established under totally xeno-free culture conditions. In addition, several subclones have been established, including a karyoptypical normal clone from a tri

See Anders Jarlert: Judisk "ras" som äktenskapshinder i Sverige. Effekten av Nürnberglagarna i Svenska kyrkans statliga funktion som lysningsförrättare 1935-1945. Malmö 2006.

Background and aims: Anti-alpha 4 integrin therapy with natalizumab is efficacious in refractory Crohn's disease and in multiple sclerosis, but carries an estimated 1/1000 risk of progressive multifocal leukoencephalopathy (PML) caused by reactivation of latent JC virus infection. Athough anti-alpha 4 integrin therapies are likely to be introduced in the clinic, screening for the risk of PML has n

The authors present fabrication and electrical measurements of InSb nanowire field-effect transistors (FETs) and quantum dots. The devices are made on a SiO2-capped Si substrate from InSb segments of InAs/InSb heterostructured nanowires, which are grown by metalorganic vapor phase epitaxy. For the FETs, both single- and dual-gate devices are fabricated. The Si substrate is employed as the back gat

Purpose The purpose is to examine various aspects of integration in order to structure and define the concept of supply chain management integration. Design/methodology/approach The study is based on an extensive literature review in three steps and a series of interviews with leading SCM consulting firms. Findings We found limited empirical research discussing SCM integration beyond the dyadi

A kinetic model for glucose and xylose co-substrate uptake in Saccharomyces cerevisiae is presented. The model couples the enzyme kinetics with the glucose-dependent genetic expression of the individual transport proteins. This novel approach implies several options for optimizing the co-substrate utilization. Interestingly, the simulations predict a maximum xylose uptake rate at a glucose concent

This paper presents DC and RF characterization as well as modeling of vertical InAs nanowire MOSFETs with LG = 200 nm and Al2O3/HfO2 high-κ dielectric. Measurements at VDS = 0.5 V show that high transconductance (gm = 1.37 mS/μm), high drive current (IDS = 1.34 mA/μm), and low on-resistance (RON = 287 Ωμm) can be realized using vertical InAs nanowires on Si substrates. By measuring the 1/f-noise,

The objective of this paper is to compare predictions with two hand-calculation methods with data from a small-scale two-room compartment fire experiment including 52 individual tests. The first method is based on two previously presented empirical models, and the second method consists of several calculation steps in order to solve a simple energy balance. The second method is based on the conser

Recension av Carl J. Richards, When the United States Invaded Russia. Woodrow Wilson’s Siberian Disaster.