Translation, that is biosynthesis of polypeptides in accordance with information encoded in the genome, is one of the most important processes in the living cell, and it has been in the spotlight of international research for many years. The mechanisms of protein biosynthesis in bacteria and in the eukaryotic cytoplasm are now understood in great detail. However, significantly less is known about

The RelA-mediated stringent response is at the heart of bacterial adaptation to starvation and stress, playing a major role in the bacterial cell cycle and virulence. RelA integrates several environmental cues and synthesizes the alarmone ppGpp, which globally reprograms transcription, translation, and replication. We have developed and implemented novel single-molecule tracking methodology to cha

Sweden is actively seeking to scale up repair activities as part of its strategy to reduce waste, transition to a circular economy, and achieve zero net emissions by 2045. In the last couple of years, several new policies to promote consumer repairs have been adopted or proposed in Sweden. However, very little is known about the socio-cultural factors that shape people's decision to repair their p

Extending the lifetime of products is seen as a key objective for realising the vision of a Circular Economy. One way to increase the lifespan of products is to enable more repair activities. However, consumers encounter a variety of barriers for repairs, prompting public authorities in Europe and the US to adopt or propose policies in support of consumer repairs. Sweden has recently adopted a cir

ObjectivesThe objectives of this study are threefold: first, we separate trust into a two-dimensional concept: ingroup trust and outgroup trust. Second, we apply both types of trust to two dependent variables: nativism and civicness, hypothesizing that respondents with ingroup trust should display higher degrees of nativism and lower degrees of civicness while the opposite should apply to responde

Expert surveys are a valuable, commonly used instrument to measure party positions. Some critics question the cross-national comparability of these measures, though, suggesting that experts may lack a common anchor for fundamental concepts such as economic left–right. Using anchoring vignettes in the 2010 Chapel Hill Expert Survey, we examine the extent of cross-national difference in expert ideol

In this article, we combine advances in both survey research and scaling techniques to estimate a common dimension for political parties across the member states of the European Union. Most previous scholarship has either ignored or assumed cross-national comparability of party placements across a variety of dimensions. The 2010 wave of the Chapel Hill Expert Survey includes anchoring vignettes wh

ObjectiveThis article explores whether there is a systematic variation in conventional and unconventional political participation as a function of in-group versus out-group trust. We postulate that the narrower the moral community is, the more political participation is restricted to conventional activity that is perceived as an obligation, as a political act to be fulfilled, something akin to cit

This article reports on the 2010 Chapel Hill expert surveys (CHES) and introduces the CHES trend file, which contains measures of national party positioning on European integration, ideology and several European Union (EU) and non-EU policies for 1999−2010. We examine the reliability of expert judgments and cross-validate the 2010 CHES data with data from the Comparative Manifesto Project and the

Party members across European democracies exercise increasing influence on parties’ policy platforms or personnel choices. This article investigates ideological (in)congruence on the left–right spectrum between members and their parties by drawing on a party membership survey of more than 10,000 individuals across seven political parties in Sweden. The results show that around two-thirds of member

Party competition in Eastern Europe faces a seeming paradox. On the one hand, research finds increased political volatility in these countries, while, on the other, some authors demonstrate inherent ideological stability in the region. This research note presents a new methodological approach to adjudicating between these two findings, and suggests that while political organisations come and go, t

This article addresses the variation of anti-corruption and anti-elite salience in party positioning across Europe. It demonstrates that while anti-corruption salience is primarily related to the (regional) context in which a party operates, anti-elite salience is primarily a function of party ideology. Extreme left and extreme conservative (TAN) parties are significantly more likely to emphasize

This article addresses the relationship between the salience of anti-elite/establishment rhetoric for political parties and party positions on European integration. Anti-establishment rhetoric is a feature of populism, which is increasingly influential in contemporary European politics. For populist parties across the continent, in several ways the European Union (EU) represents the pinnacle of el

Therapeutic apheresis (TA) as a treatment for antibody-associated vasculitis (AAV) was questioned by the PEXIVAS although the MEPEX study favored TA. The aim of this study was to evaluate the efficacy of TA to improve renal function in patients consecutively included in the WAA-apheresis registry versus patients not treated with TA. Materials and methods: Included were 192 patients that suffered f

Given any infinite tree in the plane satisfying certain topological conditions, we construct an entire function f with only two critical values ±1 and no asymptotic values such that f−1([−1, 1]) is ambiently homeomorphic to the given tree. This can be viewed as a generalization of the result of Grothendieck (see Schneps (1994)) to the case of infinite trees. Moreover, a similar idea leads to a new

Time-resolved photoemission electron microscopy (TR-PEEM) belongs to a class of experimental techniquescombining the spatial resolution of electron-based microscopy with the time resolution of ultrafast opticalspectroscopy. This combination provides insight into fundamental processes on the nanometer spatial andfemto/picosecond time scale, such as charge carrier transport in semiconductors or coll

Taxes and subsidies on foods and nutrients have the potential to promote healthier diets and thereby reduce mortality. In this study, we examine the effects of such policy instruments on Swedish public health. Specifically, we estimate the effects of food and nutrient taxes and subsidies on mortality averted and postponed in Sweden, using both demand system estimations and simulation models. We ev

Aim of this study was to explore whether differences in resting hemodynamic parameters may be associated with tilt test results in unexplained syncope. We analyzed age, gender, systolic (SBP), diastolic blood pressure (DBP) and heart rate (HR) by merging three large databases of patients considered likely to be of vasovagal reflex etiology, comparing patients who had tilt-induced reflex response w