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An investigation of the Al-Sb-V-W-oxide system for propane ammoxidation

AlSb-V-W-oxide catalysts were prepared and used for propane ammoxidation to give acrylonitrile. The preparations were characterized, both as freshly prepared and after use in propane ammoxidation, using XRD, XPS, Raman spectroscopy, and transmission electron microscopy together with electron diffraction and X-ray microanalysis. Activity tests of the freshly prepared samples reveal a remarkable act

Design of recombinant antibody microarrays for complex proteome analysis: Choice of sample labeling-tag and solid support

Antibody-based microarray is a novel technology with great potential within high-throughput proteomics. The process of designing high-performing antibody (protein) microarrays has, however, turned out to be a challenging process. In this study, we have developed further our human recombinant single-chain variable-fragment (scFv) antibody microarray methodology by addressing two crucial technologic

Interactions between indices of calcium metabolism and blood pressure during calcium infusion in humans

Calcium plays a central role in maintaining vascular tone. Recent studies indicate that there are continuous relationships between systemic calcium metabolism and BP, as over the whole range of normal and raised BPs there is an inverse correlation between plasma ionised calcium concentration and BP. Twenty-two subjects with normal or moderately elevated BP participated in the present study, undert

Five years of Ulysses dust data: 2000-2004

The Ulysses spacecraft has been orbiting the Sun on a highly inclined ellipse (i = 79 degrees, perihelion distance 1.3 AU, aphelion distance 5.4 AU) since it encountered Jupiter in 1992. Between January 2000 and December 2004, the spacecraft completed almost an entire revolution about the Sun, passing through perihelion in May 2001 and aphelion in July 2004. In this five-year period the dust detec

Glypican-1 is a vehicle for polyamine uptake in mammalian cells. A pivotal role for nitrosothiol-derived nitric oxide.

Polyamines (putrescine, spermidine, and spermine) are essential for growth and survival of all cells. When polyamine biosynthesis is inhibited, there is up-regulation of import. The mammalian polyamine transport system is unknown. We have previously shown that the heparan sulfate (HS) side chains of recycling glypican-1 (Gpc-1) can sequester spermine, that intracellular polyamine depletion increas

A novel molecular mechanism of primary resistance to FLT3-kinase inhibitors in AML

Currently, FLT3 tyrosine kinase inhibitors (TKIs) are emerging as the most promising drug therapy to overcome the dismal prognosis of acute myelogenous leukemia (AML) patients harboring internal tandem duplications (ITDs) of FLT3. However, up-front drug resistance occurs in approximately 30% of patients, and molecular mechanisms of resistance are poorly understood. Here, we have uncovered a novel

Continuous brain-function monitoring: State of the art in clinical practice.

Continuous electroencephalographic (EEG) monitoring gives direct information on brain function in newborn infants needing intensive care. To improve the possibilities of long-term monitoring, the EEG is time-compressed and recorded with a reduced number of electrodes. A trend measure of the EEG, the amptitude-integrated EEG (aEEG), has proved capable of giving relevant information in newborn infan

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A rare blood group: p phenotype. A rare blood group is usually defined as the absence of a high prevalence antigen or the absence of several antigens within a single blood group system. These individuals may develop clinically significant red cell antibodies to the high incidence red cell antigens they lack. A 33-year-old alloimmunized woman was referred to our center at the 12th week of her third

New release cell for NMR microimaging of tablets Swelling and erosion of poly(ethylene oxide)

A small release cell, in the form of a rotating disc, has been constructed to fit into the MRI equipment. The present work show that both qualitative and quantitative information of the swelling and erosion behavior of hydrophilic extended release (ER) matrix tablets may be obtained using this release cell and non-invasive magnetic resonance imaging (MRI) studies at different time-points during ma

Survivor path processing in Viterbi decoders using register exchange and traceforward

This paper proposes a new class of hybrid VLSI architectures for survivor path processing to be used in Viterbi decoders. The architecture combines the benefits of register exchange and trace-forward algorithms, that is, low memory requirement and latency versus implementation efficiency. Based on a structural comparison, it becomes evident that the architecture can be efficiently applied to codes

Chiral hexarhodium clusters containing heterobidentate phosphine ligands, a structural and reactivity study

Some intrinsically chiral [Rh6(CO)14(µ,2-PX)] clusters have been synthesized, beginning with reactions of [Rh6(CO)16–x(NCMe)x](x= 1, 2) with PX, where PX represents the bidentate bridging ligands diphenyl(benzothienyl)phosphine (1), diphenyl(2-thienyl)phosphine (2), di(2-thienyl)phenylphosphine (3), tris(2-thienyl)phosphine (4), diphenyl(2-pyridyl)phosphine (5) and diphenylvinylphosphine (6). The

Identification of mecA-related oxacillin resistance in staphylococci by the E test and the broth microdilution method

A set of 165 strains of different staphylococcal species, 67 Staphylococcus aureus, 71 novobiocin-sensitive coagulase-negative staphylococci (CNS) and 27 novobiocin-resistant CNS was used. The oxacillin and methicillin MICs were recorded after 24 and 42 h of incubation at 35 degrees C and at 30 degrees C. Significantly higher MICs were recorded at 30 degrees C compared with 35 degrees C. While a p

The association between changes in skin echogenicity and the fibroblast production of biglycan and versican in systemic sclerosis

Objective To investigate a possible association between the longitudinal changes in skin involvement and the fibroblast production of proteoglycans in vitro, among patients with early and untreated systemic sclerosis (SSc). Methods In 11 patients, 6 with diffuse cutaneous systemic sclerosis (dSSc) and 5 with limited cutaneous systemic sclerosis (lSSc), and in 6 controls skin thickness and skin ech

Long-term results of stenting for chronic iliac artery occlusion.

PURPOSE: To evaluate the long-term results of stent placement for chronic occlusions of the iliac arteries. METHODS: Between October 1992 and December 1997, 73 patients (40 men; median age 64 years, range 42-89) with 76 occluded iliac arteries (33 common, 34 external, and 9 both vessels) were treated with percutaneous recanalization and stenting using a variety of self-expanding and balloon-expand

Aquaporins and water homeostasis in plants

Aquaporins are water channel proteins of vacuolar and plasma membranes. When opened they facilitate the passive movement of water molecules down a water potential gradient. In Arabidopsis, 30 genes have been found that code for aquaporin homologues. Some of these genes code for highly abundant constitutively expressed proteins and some are known to be temporally and spatially regulated during deve