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BACKGROUND: Evidence-practice gaps exist in urology. We previously surveyed European Association of Urology (EAU) guidelines for strong recommendations underpinned by high-certainty evidence that impact patient experience for which practice variations were suspected. The recommendation "Do not offer neoadjuvant androgen deprivation therapy (ADT) before surgery for patients with prostate cancer" wa
This study explores how the Fire and Rescue Service can better prepare for solving complex problems in emergencies by using the concept of problems and problem-solving networks. Primary and secondary data from an extensive fire incident were analysed, including semi-structured interviews and incident assessment reports. Complex problems that arise during emergencies can be challenging to define, a
This paper reframes our understanding of the discourse on work-life balance (WLB) from a global perspective, where life on the four income levels (from bottom of the wealth to top of the wealth) is equally considered. Based on a systematic literature review, our initial insights are that WLB of workers in the highest economic sectors has received significant attention from scholars and practitione
Causal discovery outputs a causal structure, represented by a graph, from observed data. For time series data, there is a variety of methods, however, it is difficult to evaluate these on real data as realistic use cases very rarely come with a known causal graph to which output can be compared. In this paper, we present a dataset from an industrial subsystem at the European Spallation Source alon
Background: Communication is a key tool in the nursing profession. It is known that listeners are sensitive to the speaker's voice and interpret the speaker's intentions primarily from the non-verbal signal conveyed. Aim: To map and discuss the current state of knowledge and research evidence on professional voice use in health and nursing care. Design and Method: A scoping review adherent to the
Background: Piperacillin/tazobactam may be associated with less favourable outcomes than carbapenems in patients with severe bacterial infections, but the certainty of evidence is low. Methods: The Empirical Meropenem versus Piperacillin/Tazobactam for Adult Patients with Sepsis (EMPRESS) trial is an investigator-initiated, international, parallel-group, randomised, open-label, adaptive clinical t
Introduction: With over 360 blood group antigens in systems recognized, there are antigens, such as RhD, which demonstrate a quantitative reduction in antigen expression due to nucleotide variants in the non-coding region of the gene that result in aberrant splicing or a regulatory mechanism. This study aimed to evaluate bioinformatically predicted GATA1-binding regulatory motifs in the RHD gene f
Background: Social prescribing (SP) is a patient pathway by which healthcare professionals connect patients with other sources of support, groups, or activities within their community. The awareness, practice, and perception of SP among GPs across Europe remains unclear. Objectives: To explore the awareness, practice, and perception of GPs on SP in the WONCA Europe region. Methods: An anonymous, c
During the early modern period Swedish society was structured by a variety of hierarchies, and the principle of filial deference, or the obedience and recognition children–young or adult–were expected to show their parents, was more or less absolute. These ideas of family hierarchy influenced marriage laws and the formal rules of who was allowed to marry whom. During the 1700s the number of applic
This study examines the influence of ChatGPT on tourist behaviour using complexity theory. Factors such as media richness, anthropomorphism, trust in ChatGPT, and trust in online travel agencies are investigated to understand their effects on purchasing intentions and word-of-mouth, along with a moderator of sustainable-tourism action (practice). Results revealed the relationships among the variab
Introduction: Traumatic brain injury to thalamo-cortical pathways is associated with posttraumatic morbidity. Diffuse mechanical forces to white matter tracts and deep grey matter regions induce an inflammatory response and vascular damage resulting in progressive neurodegeneration. Pro-inflammatory cytokines, including interleukin-1β (IL-1β), may contribute to the link between inflammation and th
Hur resonerade svenska tjuvar och bedragare för 200 år sedan? Varför valde de en kriminell bana, och hur interagerade de med andra brottslingar, med bondesamhället och med rättsstatens representanter. Vad hände bakom kulisserna på dåtida häkten och fängelser? Vilka var konfliktlinjerna och finns det några likheter mellan den tidens brottsstrukturer och dagens? Med hjälp av autentiska självbiografi
Om en person på regelbunden basis skaffar sig sitt uppehälle genom att stjäla från sina medmänniskor kan man säga att vederbörande försörjer sig genom att stjäla. Varför väljer någon ett sådant leverne och hur har livsstilskriminella försvarat vad de gjort för att skaffa sig mat på bordet? I detta kapitel diskuteras hur svenska straffångar resonerade kring sitt eget tjuvaktiga beteende under
Från sekelskiftet 1800 förlorade adeln sina privilegier allt eftersom. En viktig reform om lika arv för pojkar och flickor genomdrevs 1845 mot livliga protester från adelns sida. I riddarhusets debatter framstår adeln som en konservativ grupp, inriktad på att försvara sin position och hålla samman arvfallen egendom, primärt genom att gynna söner framför döttrar. Frågan är dock i vilken utsträcknin
In this paper, we explore contemporary regional development in a historic industrial region. Specifically, we unpack the influences of industrial history and culture, built up over several centuries, on contemporary regional development dynamics and issues. In doing so, we draw on an evolutionary perspective within economic geography and perspectives from deindustrialization studies to understand
Nature-based solutions (NBS) are actions that help communities address social-ecological challenges such as flooding and polluted groundwater. Nevertheless, research shows that in practice, NBS confront several barriers in planning and implementation, many of which are related to the different attitudes of political and administrative actors. There is knowledge missing on their viewpoints on NBS.
Aims/hypothesis: Low birthweight is a risk factor for type 2 diabetes and CVD. This prospective cohort study investigated whether lower birthweight increases CVD risk after diagnosis of type 2 diabetes. Methods: Original midwife records were evaluated for 8417 participants recently diagnosed with type 2 diabetes in the Danish Centre for Strategic Research in Type 2 Diabetes (DD2) cohort. Patients
