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Immobilization of tissue iron on calcareous soil: differences between calcicole and calcifuge plants

Deficiency of P and sometimes of micronutrients; especially Fe, is of importance to the calcicole-calcifuge behaviour of plants. Calcifuge species are unable to solubilize these elements or keep them metabolically active in sufficient amounts on calcareous soils. To demonstrate if calcicole, calcifuge and 'soil indifferent' species differ in Fe nutrition dynamics, samples of such species were tran

Work ability - experiences and perceptions among physicians.

Purpose. To describe experiences and perceptions of work ability and how it can be assessed among Swedish physicians. Method. We interviewed eight men and six women in the fields of general practice, occupational health, rehabilitation and orthopaedic surgery. Qualitative content analysis was applied to the data. Results. The approach striving to support the patient in mutual confidence was what p

Characterization of shear and compaction bands in a porous sandstone deformed under triaxial compression

The study of localized deformation in porous sandstones at the laboratory scale can yield valuable insights into the internal structures and mechanisms of shear zones and compaction bands that might impact on flow at a reservoir scale. Herein, we report results of a laboratory study of shear and compaction band formation in a porous sandstone using a range of full-field experimental techniques: ac

Discrete and continuum analysis of localised deformation in sand using X-ray mu CT and volumetric digital image correlation

The objective of this work was to observe and quantify the onset and evolution of localised deformation processes in sand with grain-scale resolution. The key element of the proposed approach is combining state-of-the-art X-ray micro tomography imaging with three-dimensional volumetric digital image correlation techniques. This allows not only the grain-scale details of a deforming sand specimen t

Obesity and Risk of Recurrence in Patients with Breast Cancer Treated with Aromatase Inhibitors

Importance: Clinical studies confirm that obesity is a risk factor for recurrence in postmenopausal women with hormone receptor-positive (HR+) breast cancer. Evidence suggests that women with obesity do not obtain similar protection from aromatase inhibitors as women with healthy weight. Objective: To examine the associations of body mass index (BMI) with recurrence. Design, Setting, and Participa

Macrophage expressed tartrate-resistant acid phosphatase 5 promotes pulmonary fibrosis progression

Idiopathic pulmonary fibrosis (IPF) is a progressive lung disorder involving scarring of pulmonary tissue and a subsequent decrease in respiratory capacity, ultimately resulting in death. Tartrate resistant acid phosphatase 5 (ACP5) plays a role in IPF but the exact mechanisms are yet to be elucidated. In this study, we have utilized various perturbations of the bleomycin mouse model of IPF includ

Endocytic Roles of Glycans on Proteins and Lipids

Most cell surface proteins are decorated by glycans, and the plasma membrane is rich in glycosylated lipids. The mechanisms by which the enormous complexity of these glycan structures on proteins and lipids is exploited to control glycoprotein activity by setting their cell surface residence time and the ways by which they are taken up into cells are still under active investigation. Here, two mec

Development of an Implementation Strategy Tailored to Deliver Evidence-Based and Person-Centred Nursing Care for Patients with Community-Acquired Pneumonia : An Intervention Mapping Approach

Community-acquired pneumonia is a serious public health problem, and more so in older patients, leading to high morbidity and mortality. However, this problem can be reduced by optimising in-hospital nursing care. Accordingly, this study describes a systematic process of designing and developing a tailored theory- and research-based implementation strategy that supports registered nurses (RNs) in

3D Heisenberg universality in the van der Waals antiferromagnet NiPS3

Van der Waals (vdW) magnetic materials are comprised of layers of atomically thin sheets, making them ideal platforms for studying magnetism at the two-dimensional (2D) limit. These materials are at the center of a host of novel types of experiments, however, there are notably few pathways to directly probe their magnetic structure. We confirm the magnetic order within a single crystal of NiPS3 an

Tracing Smartphone-Enabled Customer Journeys : A Socio-Material Approach

This doctoral thesis delves into the transformation of the customer journey—that is, the direct and indirect interactions between a customer and retailer over time—in the smartphone era. Using a socio-material perspective, it goes beyond current visions of the customer journey, which often focus on emotions and experiences, and instead explores how agency is distributed across elements that includThis doctoral thesis delves into the transformation of the customer journey—that is, the direct and indirect interactions between a customer and retailer over time—in the smartphone era. Using a socio-material perspective, it goes beyond current visions of the customer journey, which often focus on emotions and experiences, and instead explores how agency is distributed across elements that includ

Civil Society Elites and State Consecration : Acceptance, Ambivalence and Rejection of Royal Honours in the UK

Elites are often offered prestigious state prizes and awards. Although most elites accept, prestigious prizes constitute a challenge for others since institutional symbolic capital cannot be merely accepted, but requires careful negotiation and management. This article investigates the dilemma of being consecrated by the state by studying civil society elites’ reception and use of royal honours, t

USP7 controls NGN3 stability and pancreatic endocrine lineage development

Understanding the factors and mechanisms involved in beta-cell development will guide therapeutic efforts to generate fully functional beta cells for diabetes. Neurogenin 3 (NGN3) is the key transcription factor that marks endocrine progenitors and drives beta-cell differentiation. Here we screen for binding partners of NGN3 and identify the deubiquitylating enzyme USP7 as a key regulator of NGN3