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Dental Implant Quality Register—A possible tool to further improve implant treatment and outcome

The Board of EAO (European Association for Osseointegration) has discussed an initiative to explore the conditions to establish a Dental Implant Register. It was suggested to bring this issue to the EAO Consensus Conference 2018 for a discussion and to possibly propose relevant and manageable parameters. This article presents some select examples from quality registers in the medical field. Based

The Tycho-Gaia Astrometric Solution

Gaia DR1 is based on the first 14 months of Gaia's observations. This is not long enough to reliably disentangle the parallax effect from proper motion. For most sources, therefore, only positions and magnitudes are given. Parallaxes and proper motions were nevertheless obtained for about two million of the brighter stars through the Tycho-Gaia astrometric solution (TGAS), combining the Gaia obser

GaiaNIR - A future all-sky astrometry mission

With the launch of Gaia in December 2013, Europe entered a new era of space astrometry following in the footsteps of the very successful Hipparcos mission. A weakness of Gaia is that it only operates at optical wavelengths. However, much of the Galactic centre and the spiral arm regions are obscured by interstellar extinction. An obvious improvement on Gaia is to include the Near-Infra-Red (NIR) w

Optical properties of III-nitride semiconductors

The optical properties of the group-III-nitride materials are obviously of direct relevance for optoelectronic applications, but experiments measuring optical properties also give information on a range of electronic properties. There is already a wealth of data in the literature on the optical properties of III-nitrides [1-4], and here we will concentrate on some of the most recent additions to t

Transcription factor programming of human ES cells generates functional neurons expressing both upper and deep layer cortical markers

Human neurodegenerative disorders affect specific types of cortical neurons. Efficient protocols for the generation of such neurons for cell replacement, disease modeling and drug screening are highly warranted. Current methods for the production of cortical neurons from human embryonic stem (ES) cells are often time-consuming and inefficient, and the functional properties of the generated cells h

Familial risks of ovarian cancer by age at diagnosis, proband type and histology

Ovarian cancer is a heterogeneous disease. Data regarding familial risks for specific proband, age at diagnosis and histology are limited. Such data can assist genetic counseling and help elucidate etiologic differences among various histologic types of ovarian malignancies. By using the Swedish Family-Cancer Database, we calculated relative risks (RRs) for detailed family histories using a two-wa

Exploitation of Host Signal Transduction Pathways Induced by Streptococcus pneumoniae

The induction of host signal transduction cascades by bacterial pathogens contributes directly to their virulence. In addition to the pore-forming cytolysin pneumolysin, several surface-exposed proteins of Streptococcus pneumoniae are also potent modulators of complex host signaling pathways. These pneumococcal surface proteins either directly mediate adhesion of pneumococci to specific cell surfa

Simultaneous saccharification and co-fermentation for bioethanol production using corncobs at lab, PDU and demo scales

The global CO2 emissions in 2010 from fossil energy use grew at the fastest rate since 1969. The year 2010 also witnessed that the global oil production did not match the rapid growth in consumption [1]. These recent data further intensify worldwide concerns about greenhouse gas emissions and energy security for a sustained economic development. For a reduced dependence on oil from fossil reserves

HIV-genetic diversity and drug resistance transmission clusters in Gondar, Northern Ethiopia, 2003-2013

Background The HIV-1 epidemic in Ethiopia has been shown to be dominated by two phylogenetically distinct subtype C clades, the Ethiopian (C'-ET) and East African (C-EA) clades, however, little is known about the temporal dynamics of the HIV epidemic with respect to subtypes and distinct clades. Moreover, there is only limited information concerning transmission of HIV-1 drug resistance (TDR) in t

Dietary intake of total polyphenol and polyphenol classes and the risk of colorectal cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort

Polyphenols may play a chemopreventive role in colorectal cancer (CRC); however, epidemiological evidence supporting a role for intake of individual polyphenol classes, other than flavonoids is insufficient. We evaluated the association between dietary intakes of total and individual classes and subclasses of polyphenols and CRC risk and its main subsites, colon and rectum, within the European Pro

AMPK activation by A-769662 and 991 does not affect catecholamine-induced lipolysis in human adipocytes

Activation of AMP-activated protein kinase (AMPK) is considered an attractive strategy for the treatment of type 2 diabetes. Favorable metabolic effects of AMPK activation are mainly observed in skeletal muscle and liver tissue whereas the effects in human adipose tissue are only poorly understood. Previous studies, which largely employed the AMPK activator 5-aminoimidazole-4-carboxamide-1-D-ribof