Radioresistance, the failure to achieve a desired outcome, is an obstacle in clinical radiotherapy. In this thesis we investigate factors affecting radioresistance and strategies to overcome it, both with established clinical approaches and by using novel pre-clinical discoveries. Study I & II concern the impact of tumour volume in patients with oropharyngeal cancer. In a large, pooled cohort

This letter proposes a two-port MIMO smartphone antenna for frequency bands below 1 GHz, which is robust to user effects. The design is achieved by first analyzing the characteristic modes of a chassis that includes the large screen. Two modes predicted to be less affected by the user than other commonly used modes are selected. The modal currents and near-fields of the two desired modes then guid

The rise in CDOM (coloured dissloved organic matter) is likely to be relatively more pronounced in remote northern regions. However, there is a lack of monitoring to confirm this. For this reason, there is a strong incentive to develop remote sensing-based methods to map CDOM in lakes across broader geographical scales and to include geograghic contex in such analysis. There is a lack of understan

The concept of “Sustainable water use” (SWU) aims to assure three pillars of sustainability related to the water sector: the social, environmental, and economical. Industrial development, especially in developing countries, requires an adequate response, as industrial activities are recognized as one of the major sources of water pollution, what leads to deterioration of environmental safety and w

We introduce the natural notion of (p,q)-harmonic morphisms between Riemannian manifolds. This unifies several theories that have been studied during the last decades. We then study the special case when the maps involved are complex-valued. For these we find a characterisation and provide new non-trivial examples in important cases.

Sexual dimorphism is typically thought to result from sexual selection for elaborated male traits, as proposed by Darwin. However, natural selection could reduce expression of elaborated traits in females, as proposed by Wallace. Darwin and Wallace debated the origins of dichromatism in birds and butterflies, and although evidence in birds is roughly equal, if not in favor of Wallace's model, butt

Soaking small molecules into the solvent channels of protein crystals is the most common method of obtaining crystalline complexes with ligands such as substrates or inhibitors. The solvent channels of some protein crystals are large enough to allow the incorporation of macromolecules, but soaking of protein guests into protein crystals has not been reported. Such protein host crystals (here given

Achieving consumer loyalty will remain a prime objective of every business in the current volatile, uncertain, complex and ambiguous environment (VUCA), which demands some out-of-thebox thinking on the part of policymakers to sustain the competitive advantage. Sustainability has been emerging as a “new normal” for all industries of the present era, which forces all sectors to incorporate it into t

Crowdfunding is emerging as a significant means by which to finance and advance the 17 United Nations Sustainable Development Goals (SDGs). Generating financial support for the SDGs is now of even more importance because of the economic impacts of COVID-19. However, little research on sustainability crowdfunding has been conducted, particularly with respect to how behavioral influences, such as pe

Due to its compatible oxygen-transporting abilities, hemoglobin (Hb) is a protein of interest in the development of artificial oxygen therapeutics. Despite continuous formulation attempts, extracellular Hb solution often exhibits undesirable reactions when applied in vivo. Therefore, protein engineering is frequently used to examine alternative ways of controlling the unwanted reactions linked to

Background: Acute lower limb ischaemia (ALI) is a life and limb threatening vascular emergency. Acute compartment syndrome (ACS) may develop upon revascularization. The risk of fasciotomy was hypothesized to be decreased in women due to their lower calf muscle mass. The main aim was to evaluate risk factors for fasciotomy after revascularization for ALI. Methods: This is a retrospective observatio

The incidence of type 1 diabetes in children is growing and optimal treatment is needed to prevent or delay complications. Insulin degludec is a new basal insulin with ultra-long effect. However, there are few published studies in children and adolescents. The first aim was to compare HbA1c levels in children and adolescents who received degludec from onset, to age/gender matched controls with oth

Aims To establish normative values of vibration perception thresholds (VPTs), using multi-frequency vibrometry at finger pulps and at metatarsal heads of the foot in healthy adults. We also aimed to investigate factors that could potentially affect VPTs such as age, sex, height, weight, foot- or handedness and skin temperature. Methods VPTs were examined in 924 healthy and randomly selected subjec

Background: Factors predicting long-term prognosis in patients with acute dyspnea may guide both acute management and follow-up. The aim of this study was to identify socioeconomic and clinical risk factors for all-cause mortality among acute dyspnea patients admitted to an Emergency Department. Methods: We included 798 patients with acute dyspnea admitted to the ED of Skåne University Hospital, M