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Natural Language Response Formats for Assessing Depression

OBJECTIVE:Recent advances in AI-based Large Language Models (LLM) can transform individuals’ descriptions of emotional health into numeric representations that predict rating scales with an accuracy approaching theoretical upper limits. This advancement enables examing various open-ended response formats. We develop and evaluate formats ranging from closed to more open: 1) selecting descriptive wo

Long-Term Changes to the Microbiome, Blood Lipid Profiles and IL-6 in Female and Male Swedish Patients in Response to Bariatric Roux-en-Y Gastric Bypass

Lipid metabolism dysregulation is a critical factor contributing to obesity. To counteract obesity-associated disorders, bariatric surgery is implemented as a very effective method. However, surgery such as Roux-en-Y gastric bypass (RYGB) is irreversible, resulting in life-long changes to the digestive tract. The aim of the present study was to elucidate changes in the fecal microbiota before and

C-Myc protein expression indicates unfavorable clinical outcome in surgically resected small cell lung cancer

Background: By being highly involved in the tumor evolution and disease progression of small cell lung cancer (SCLC), Myc family members (C-Myc, L-Myc, and N-Myc) might represent promising targetable molecules. Our aim was to investigate the expression pattern and prognostic relevance of these oncogenic proteins in an international cohort of surgically resected SCLC tumors. Methods: Clinicopatholo

A cathodoluminescence study of InP/InGaP axially heterostructured NWs for tandem solar cells

Axially heterostructured nanowires (NWs) constitute a promising platform for advanced electronic and optoelectronic nanodevices. The presence of different materials in these NWs introduces a mismatch resulting in complex strain distributions susceptible of changing the band gap and carrier mobility. The growth of these NWs presents challenges related to the reservoir effect in the catalysts drople

Diagnostic confidence with quantitative cardiovascular magnetic resonance perfusion mapping increases with increased coverage of the left ventricle

Background: Quantitative cardiovascular magnetic resonance (CMR) first pass perfusion maps are conventionally acquired with 3 short-axis (SAX) views (basal, mid, and apical) in every heartbeat (3SAX/1RR). Thus, a significant part of the left ventricle (LV) myocardium, including the apex, is not covered. The aims of this study were 1) to investigate if perfusion maps acquired with 3 short-axis view

Keeping in time : The design of qualitative longitudinal research in SLA

Language development is a long-term process. Individual-level longitudinal case studies have been foundational to SLA. However, methodologies that can support person-focused and process-oriented research lack consolidation. Qualitative longitudinal (QL) research (Neale, 2021a, 2021b) is a methodology that facilitates exploration of the influences of time over time. It provides a temporal architect

Lagspråk och skriftlighet : Det formella skriftspråkets konstruktionssyntax som grund för lagspråksförenkling och EU-översättning

Den här boken handlar om de lexikogrammatiska förutsättningarnaför välfungerande och rimligt lättillgängliga inhemska lagtexter ochöversatta EU-rättsakter och -domar. Bokens huvudtes är attspråkformen i bägge fallen måste grundas på skriftlighet, dvs. på ettkvalificerat bruk av hela det formella skriftspråketskonstruktionsregister och med strikt tillämpning av dess generellanormsystem. Boken vände

Landscape and management influences on smallholder agroforestry yields show shifts during a climate shock

Sustaining yields for smallholder perennial agriculture under a rapidly changing climate regime may require consideration of landscape features and on-farm management decisions in tandem. Optimising landscape and management may not be possible for maximising yields in any one year but maintaining heterogeneous landscapes could be an important climate adaptation strategy. In this study, we observed

The dispute between Ethiopia and Egypt over the Grand Ethiopian Renaissance Dam

The construction of large hydro infrastructures often causes severe socio-environmental issues. When the facility is projected on transboundary rivers, such as the Nile, these issues may become political and involve a much greater number of actors. The Grand Ethiopian Renaissance Dam (GERD) is provoking significant geopolitical tensions in the Horn of Africa since it involves two of the most dynam

Taking a long view towards quality improvement : an intentional approach to solving wicked problems and improving student experience

Quality enhancement projects in universities frequently rely on short-term, fragmented studies implemented in response to snapshot data linked to student feedback. Such projects may not address the complex interplay across stakeholder groups and do not always acknowledge the unintended consequences of change. This article, focused on systems design, draws on research conducted over seventeen years

Synthesis of gem-Difluorinated 2,3-Dihydrobenzofurans Using Freon-22 via [4 + 1] Annulation of Difluorocarbene and Antitumor Activity Evaluation

As an inexpensive industrial chemical, chlorodifluoromethane (Freon-22), despite its relatively low reactivity, can serve as a practical CF2 source for the construction of gem-difluorinated ring structures. Here, we develop a protocol for the efficient assembly of valuable fluorinated 2,3-dihydrobenzofurans from the [4 + 1] annulation in good yields under basic conditions. The reliable practicabil

The Whorfian time warp : Representing duration through the language hourglass

How do humans construct their mental representations of the passage of time? The universalist account claims that abstract concepts like time are universal across humans. In contrast, the linguistic relativity hypothesis holds that speakers of different languages represent duration differently. The precise impact of language on duration representation is, however, unknown. Here, we show that langu

Enhanced surveillance of hospitalized COVID-19 patients in Europe : an evaluation of the I-MOVE-COVID-19 surveillance network

Background: A pre-existing, well-established European influenza surveillance network known as I-MOVE enabled the rapid implementation of a European multi-country COVID-19 hospital surveillance network for surveillance of hospitalized COVID-19 cases in early 2020. This network included 257 hospitals in 11 surveillance sites across nine countries. We aimed to identify whether the surveillance object

Majorana Qubits and Non-Abelian Physics in Quantum Dot-Based Minimal Kitaev Chains

The possibility of engineering artificial Kitaev chains in arrays of quantum dots coupled via narrow superconducting regions has emerged as an attractive way to overcome the disorder issues that complicate the realization and detection of topological superconducting phases in other platforms. Although a true topological phase would require long chains, a two-site chain realized in a double quantum

Switching Off Vascular MAPK Signaling : A Novel Strategy to Prevent Delayed Cerebral Ischemia Following Subarachnoid Hemorrhage

Patients who initially survive the rupture and repair of a brain aneurysm often take a devastating turn for the worse some days later and die or suffer permanent neurologic deficits. This catastrophic sequela is attributed to a delayed phase of global cerebral ischemia (DCI) following aneurysmal subarachnoid hemorrhage (aSAH), but we lack effective treatment. Here we present our view, based on 20