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FS-GBDT : identification multicancer-risk module via a feature selection algorithm by integrating Fisher score and GBDT

Cancer is a highly heterogeneous disease caused by dysregulation in different cell types and tissues. However, different cancers may share common mechanisms. It is critical to identify decisive genes involved in the development and progression of cancer, and joint analysis of multiple cancers may help to discover overlapping mechanisms among different cancers. In this study, we proposed a fusion f

Contact Allergy to Oxidized Linalool and Oxidized Limonene is Over-represented in Individuals with Photocontact Allergy to Ketoprofen

Simultaneous contact allergies are common in individuals with photocontact allergy to ketoprofen. The rate of contact allergy to the fragrance substances oxidized linalool and oxidized limonene in ketoprofen-photo-allergic individuals were investigated in comparison with the corresponding rates in individuals without photo-contact allergy to ketoprofen, using Fisher's exact test. A total of 4,021

Sex differences in postural orientation errors and association with objective and patient-reported function in patients with ACL injury : An exploratory cross-sectional study

Objectives There is limited research on sex differences in postural orientation (ie, alignment between body segments) in people with knee injury measured with a clinically applicable method. An understanding of the relationship between postural orientation and physical function may help guide decision making in rehabilitation. The aims were to evaluate (1) sex differences in visual assessment of P

Psychotropic Drugs in Patients with Cushing's Disease Before Diagnosis and at Long-Term Follow-Up : A Nationwide Study

CONTEXT: Psychiatric symptoms are common in Cushing's disease (CD) and seem only partly reversible following treatment. OBJECTIVE: To investigate drug dispenses associated to psychiatric morbidity in CD patients before treatment and during long-term follow-up. DESIGN: Nationwide longitudinal register-based study. SETTING: University Hospitals in Sweden. SUBJECTS: CD patients diagnosed between 1990

Bioolja från befintliga kraftvärmeverk-en systemstudie : Sammanfattning av ett forskningssamarbete mellan Lunds Tekniska Högskola, Karlstad universitet och Kraftringen Energi

Samhällets pågående omställning mot minskade utsläpp av växthusgaser kräver bland annat stora mängder fasta biobränslen och flytande biodrivmedel. Den svenska biobränslepotentialen domineras av bi- och restprodukter från skogen, som sågspån från sågverken och grenar och toppar (sk grot) från avverkning av skog. Att omvandla trä till flytande bränslen med hög omvandlingseffektivitet är utmanande, o

Interval breast cancer rates and tumor characteristics in the prospective population-based Malmö breast tomosynthesis screening trial

Background: Interval cancer rates can be used to evaluate whether screening with digital breast tomosynthesis (DBT) contributes to a screening benefit. Purpose: To compare interval cancer rates and tumor characteristics in DBT screening to those in a contemporary population screened with digital mammography (DM). Materials and Methods: The prospective population-based Malmö Breast Tomosynthesis Sc

Income-based inequality in full immunization coverage of children aged 12-23 months in Eastern India : A decomposition analysis

IntroductionNotably, less than two-thirds of under-5 children received full immunization in 2016 in India. It is critical to understand the inequalities in access to immunization for determining an effective health policy agenda to ensure universal health coverage. Hence, we performed a study to assess the determinants of income-based inequality in the full immunization of children aged 12–23 usin

Herrens år 1399

Det är Herrens år 1399. Tyska orden försöker upprätthålla lag och ordning på Gotland strax efter att Kalmarunionen grundats. En man har nyligen hittats hängd i en ödegård norr om Visby. Det visar sig vara en rik borgare från Stockholm. Mördaren har sprättat upp hans mage och slängt trettio silverpenningar på marken under honom en kopia av hur Judas Iskariots död brukar avbildas. Bara några steg fr

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The pulp and paper industry is one of the most important industrial sectors worldwide and has great potential to be a cornerstone for the future bioeconomy, especially for lignocellulosic biorefineries. The potential of membrane processes in this transformation is shown in three examples from the fields of Kraft / Sulphate, Sulphite and thermomechanical pulping. In addition, the challenges of memb

Open-access portal with hindcast wave data for Skåne and Halland

Wave climate data for the Swedish provinces Skane and Halland, were hindcast using SWAN, a third-generation spectral wave model. The 40-year wave dataset, from 1979 to 2019, is made available through an open-access data portal (https://gis.sgi.se/vagmodell/). The wave data has a three-hour resolution and includes significant wave height, peak wave period, and wave direction. The wave model domain

Comparison of RNA- and DNA-based methods for measurable residual disease analysis in NPM1-mutated acute myeloid leukemia

Introduction: Reverse transcriptase quantitative PCR (RT-qPCR) is considered the method of choice for measurable residual disease (MRD) assessment in NPM1-mutated acute myeloid leukemia (AML). MRD can also be determined with DNA-based methods offering certain advantages. We here compared the DNA-based methods quantitative PCR (qPCR), droplet digital PCR (ddPCR), and targeted deep sequencing (deep

Revealing perturbation responses with limited observations of biological communities

Restrictions in empirical research of biological communities have limited our understanding of the combined influence of environmental variability and system structure on community composition. Spatial patterns of community composition in less accessible systems, such as marine benthos, can often not be explained by many factors beyond the direct impact of the environment on community members. We

Co-designed 3+3 port dual-band broadside tri-modal patch antenna

A co-designed (3+3)-port antenna for dual-band operation that requires no feeding or decoupling network is proposed and verified. The antenna consists of six ports which are divided into two groups that resonate in two differentfrequency ranges. The basic radiating element is a tri-modal patch in a folded snowflake-shaped structure with the largest antenna dimension of 0.48λ1 or 0.68λ2, where λ1 and