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Host Immunity-Microbiota-Virus Interactions at the Intestinal Mucosal surface in Health and Disease

The presence of viral immune triggers at the intestinal mucosa can have multipleglobal effects on intestinal integrity, including relative protection fromsubsequent inflammatory bowel disease. During the last century, the westernworld has achieved a remarkable success in preventing infectious diseases,which increased the general life expectancy dramatically. However, theincidence and prevalence of

Match length realization and cooperation in indefinitely repeated games

Experimental studies of infinitely repeated games typically consist of several indefinitely repeated games (“matches”) played in sequence with different partners each time, whereby match length, i.e. the number of stages of each game is randomly determined. Using a large meta data set on indefinitely repeated prisoner's dilemma games (Dal Bó and Fréchette, 2018) we demonstrate that the realized le

Circular business models for the fastmoving consumer goods industry : Desirability, feasibility, and viability

Fast-moving consumer goods (FMCGs) are products that have a short useful lifetime and are typically designed for single or limited uses followed by disposal. The disposable nature of FMCGs combined with ineffective waste recovery systems is causing global environmental problems. Various reusable packaging business models have emerged to tackle these problems; however, their influence is still low

Mother's Own Milk and Its Relationship to Growth and Morbidity in a Population-based Cohort of Extremely Preterm Infants

Objectives:The aim of the study was to evaluate the relationships between intake of mother's own milk (MOM), compared with intake of pasteurized donor milk (DM), and postnatal growth, incidence of retinopathy of prematurity (ROP) and bronchopulmonary dysplasia (BPD), in extremely preterm infants.Methods:Swedish population-based cohort of surviving extremely preterm infants born 2004 to 2007. Expos

Paediatric diagnostic reference levels for common radiological examinations using the European guidelines

Objective: The purpose of this study was to explore the feasibility to determine regional diagnostic reference levels (RDRLs) for paediatric conventional and CT examinations using the European guidelines and to compare RDRLs derived from weight and age groups, respectively. Methods: Data were collected from 31 hospitals in 4 countries, for 7 examination types for a total of 2978 patients. RDRLs we

Human studies of mitochondrial biology demonstrate an overall lack of binary sex differences : A multivariate meta-analysis

Mitochondria are maternally inherited organelles that play critical tissue-specific roles, including hormone synthesis and energy production, that influence human development, health, and aging. However, whether mitochondria from women and men exhibit consistent biological differences remains unclear, representing a major gap in knowledge. This meta-analysis systematically examined four domains an

A Palette of Fluorescent Aβ42 Peptides Labelled at a Range of Surface-Exposed Sites

Fluorescence-based single molecule techniques provide important tools towards understanding the molecular mechanism of complex neurodegenerative diseases. This requires efficient covalent attachment of fluorophores. Here we create a series of cysteine mutants (S8C, Y10C, S26C, V40C, and A42C) of Aβ42, involved in Alzheimer’s disease, based on exposed positions in the fibril structure and label the

Neurodevelopmental disorders and somatic diagnoses in a national cohort of children born before 24 weeks of gestation

AIM: This study investigated childhood diagnoses in children born extremely preterm before 24 weeks of gestation.METHODS: Diagnoses of neurodevelopmental disorders and selected somatic diagnoses were retrospectively retrieved from national Swedish registries for children born before 24 weeks from 2007 to 2018. Their individual medical files were also examined.RESULTS: We studied 383 children born

Climate change and land degradation in Africa : A case study in the Mount Elgon region, Uganda

The aim of this study is to estimate and compare soil erosion, in the Mount Elgon region, eastern Uganda, during the last decade. Possible trends and changes in erosion are linked to precipitation/climate change as well as changes in land cover. Two different versions of the Revised Universal Soil loss Equation RUSLE. are implemented and compared, one using slope length and the other using flow ac

Estimating surface flow over digital elevation models using a new improved form-based algorithm

This paper discusses new improvements of a form-based algorithm, which is used to estimate flow distribution over a continuous surface. In the new form- based algorithm (IFBFD), cells in a DEM are classified into five different classes. The classes are Peaks, Complicated, Sinks, Flats and Undisturbed cells. The method of how to estimate the flow distribution from each cell depends on its class. Es

Estimating slope from raster data : A test of eight different algorithms in flat, undulating and steep terrain

Eight frequently used slope algorithms based on a DEM (Digital Elevation Model) have been compared in flat, gently sloping/undulating, and steep terrain in order to investigate differences in estimated results. The matter of scale/resolution has not been considered, and the focus has not been on comparing the estimates with "ground truth" data but on comparisons between the different algorithms. P

Integration of geomatics in research & development

The use of Geographical Information Systems (GIS) within the society as well as in academic work has increased rapidly over the last decades. This also means that Geomatics has started to create problems in both academic and non-academic worlds. Firstly because it bridges borders that have been in place for a long time and secondly because Geomatics, or rather the basic concepts of Geomatics, is i

An integrated raster-tin surface flow algorithm

In this chapter, an alternative surface flow algorithm is presented. The basic idea behind the algorithm is the use of the advantages of TIN-based algorithms within a raster based environment. A gridded raster DEM is used to create a ‘regular TIN’, over which surface flow is estimated. Since each facet in the TIN has a constant slope and slope direction, the estimations of, for example, flow veloc

Comparison of algorithms for classifying Swedish landcover using Landsat TM and ERS-1 SAR data

Sixteen landcover classes in a representative Swedish environment were analyzed and classified using one Landsat TM scene and seven ERS-1 SAR.PRI images acquired during 1993. Spectral and backscattering signature separabilities are analyzed using the Jeffries-Matusita distance measure to determine which combinations of channels/images contained the most information. Maximum likelihood, sequential

On the ground estimation of vegetation cover in Australian rangelands

A number of field techniques were assessed on their reliability for estimating vegetation cover in Australian rangelands. The field sampling was undertaken using visual estimation, line intercepts, a crown cover model, and images acquired from a digital camera. The results from these methods were compared and analysed. The data obtained from these differing methods agree with each other in relativ

Prediction of surface water turnover time in coastal waters using digital bathymetric information

This paper presents a new type of geographical information system (GIS) for scientific planning of coastal waters. One hypothesis in the work is that the morphometry of the coast plays a significant role for how the water system functions as a receiving water system, for example, as a receiver of industrial and urban pollution and in response to various forms of aquaculture. A digital technique fo

On the accuracy of the global positioning system-a test using a hand-held receiver

This study aims to evaluate the accuracy of location (x, y and z) using a Magellan GPS NAV 1000 receiver. The position of a known reference point was compared with 50 fix points measured in two-dimensional (2D) mode (x, y) and with 50 fix points measured in three-dimensional (3D) mode (x, y and z). The mean errors and the root mean square errors (RMSE) in the Euclidian distances between the refere

Persons’ experiences of having hypertension – an interview study

Backgroundamong the 1–1.5 billion persons with hypertension globally only, 20–30% have controlled blood pressure (BP). The most important problem identified is non-adherence to treatment, i.e., failure to change lifestyle and to take prescribed medication. Knowledge about the reasons for this is limited.ObjectivesThe aim of the study was to explore people's experiences of having hypertension.Desig

Environmental threats and activism against extractive industries : The case of gold mining in Rosia Montană, Romania

Extractive industries often promise prosperity to less economically developed regions of the world. However, projects that rely on extractive industries such as mining often pose significant environmental threats to the host regions. The tension between economic promises and environmental impacts can spark significant conflict in rural communities. This study analyzes a proposed mining project in