Popular Abstract in Swedish Blodcirkulationen fungerar i kroppen som ett transport system för proteiner, syre och andra metaboliter. Blodet har den svåra uppgiften att vara flytande och samtidigt kunna koagulera på ställen där kärlet går sönder. Störning i denna balans leder till sjukdomar som hjärtinfarkt och blodpropp eller motsatsen svåra blödningar. Det protein som jag har studerat ingår vid The subject of this thesis is the activated protein C (APC)-mediated inactivation of factor Va. The activated form of factor V (FVa) is a procoagulant cofactor for Factor Xa (FXa) in the conversion of prothrombin to thrombin. The procoagulant function of FVa is down regulated by APC through proteolytic cleavage at three sites, Arg306, Arg506 and Arg679. The cleavage at Arg506 is kinetically favore

I det tidiga 1800-talet började man resonera kring hjälpinsatser åt fängelsefångar. I mitten av samma sekel började hjälpen och behandlingen skiljas ut från straffet, olika personer skötte olika uppgifter: Fångvaktarna skötte straffet och föreningar behandlingen. Föreningarna var ett komplement till fängelset vid cellfängelsereformen i mitten av 1800-talet I Sverige hade de bildats på statens init

Land development often results in adverse environmental impact for surface and subsurface water systems. For areas close to the coast, land changes may also result in seawater intrusion into coastal aquifers. Due to this, it is important to evaluate potential adverse effects in advance of any land development. For evaluation purposes a combined groundwater recharge model is proposed with a quasi t

The manipulation of cells and microparticles within microfluidic systems using external forces is valuable for many microscale analytical and bioanalytical applications. Acoustofluidics is the ultrasound-based external forcing of microparticles with microfluidic systems. It has gained much interest because it allows for the simple label-free separation of microparticles based on their mechanical p

Popular Abstract in SwedishProteiner består av långa kedjor av aminosyrer sammanlänkade med en så kallad peptidbindning. Proteinet är således en organisk molekyl och den har en hög molekylvikt som mäts i kilodalton (kDa). Proteiner kan agera som enzymer dvs de underlättar en biokemisk rektion. Ett protein kan vara funktionellt som en enhet och kallas då monomer. Ibland behövs flera proteiner, antiProteins are found on the inside, in the membrane, on the surface and on the outside of cells. They form complicated structures and they interact with other molecules and proteins. Protein complexes and protein-protein interactions are challenging to investigate and in the beginning of protein research most studies were done with single proteins, often in water. Although, in vivo proteins rarely f

The subject for this paper is the role of the Holocaust in contemporary European politics of identity. The Council of Europe and the European Parliament have recently adopted resolutions about the Holocaust and most European states are now member of the Holocaust Task Force. In international relations the acknowledgment of the nation’s role in the history of the Holocaust has become increasingly i

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Wear in forming tools and contact problems between sheet-metal and tool-material are common problems in manufacturing industries and sheet-metal-parts production. In this paper recent tool material experiences are presented. Quantitative determination of wear has been performed using micro hardness indentions made on the tool surface prior to pressings and thereafter measured. Wear tests are perfo

This study is a description of an effort to investigate contractors’ and subcontractors’ views of how incentives relates to partnering. In order to understand the contractual relationship between the contractor and subcontractor in partnering projects data were collected by using archive materials, on-site observation and through interviews. The result from the document analysis and observations w