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Distinct Serotypes of Streptococcal M Proteins Mediate Fibrinogen-Dependent Platelet Activation and Proinflammatory Effects

Sepsis is a life-threatening complication of infection that is characterised by a dysregulated inflammatory state and disturbed hemostasis. Platelets are the main regulators of hemostasis, and they also respond to inflammation. The human pathogen Streptococcus pyogenes can cause local infection that may progress to sepsis. There are more than 200 different serotypes of S. pyogenes defined accordin

Water assessment in transboundary river basins : the case of the Medjerda River Basin

Water resources in the Middle East and North Africa (MENA region) face over-exploitation and over-pollution due to population growth, climate change and the lack of advanced water governance approaches. These challenges become more serious in transboundary river basins and may lead to conflict between riparian countries. The main objective of this paper is to assess water resources and needs at th

Assessing combined object and mutual shading on the performance of a solar field

To make well-informed decisions on the implementation of solar energy on roofs within the urban environment, a new method was developed and described that could support such decision-making. This method takes both the mutual shading and shading from external objects into account. The method consists of the following six steps: 1) construction of the scene, 2) performance of annual solar irradiatio