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Nordugrid ARC Datastaging and Cache: Efficiency gains on HPC and cloud resources

The Worldwide LHC Computing Grid (WLCG) is today comprised of a range of different types of resources such as cloud centers, large and small HPC centers, volunteer computing as well as the traditional grid resources. The Nordic Tier 1 (NT1) is a WLCG computing infrastructure distributed over the Nordic countries. The NT1 deploys the Nordugrid ARC-CE, which is non-intrusive and lightweight, origina

Impact of different compilers and build types on Geant4 simulation execution time

Experimental observations and advanced computer simulations in High Energy Physics (HEP) paved the way for the recent discoveries at the Large Hadron Collider (LHC) at CERN. Currently, Monte Carlo simulations account for a very significant amount of computational resources of the Worldwide LHC Computing Grid (WLCG). The current growth in available computing performance will not be enough to fulfil

Studies of GEANT4 performance for different ATLAS detector geometries and code compilation methods

Full detector simulation is known to consume a large proportion of computing resources available to the LHC experiments, and reducing time consumed by simulation will allow for more profound physics studies. There are many avenues to exploit, and in this work we investigate those that do not require changes in the GEANT4 simulation suite. In this study, several factors affecting the full GEANT4 si

New developments in cost modeling for the LHC computing

The increase in the scale of LHC computing during Run 3 and Run 4 (HL-LHC) will certainly require radical changes to the computing models and the data processing of the LHC experiments. The working group established by WLCG and the HEP Software Foundation to investigate all aspects of the cost of computing and how to optimise them has continued producing results and improving our understanding of

Cardiorenal function and survival in in-hospital cardiac arrest : A nationwide study of 22,819 cases

Background: We studied the association between cardiorenal function and survival, neurological outcome and trends in survival after in-hospital cardiac arrest (IHCA). Methods: We included cases aged ≥ 18 years in the Swedish Cardiopulmonary Resuscitation Registry during 2008 to 2020. The CKD-EPI equation was used to calculate estimated glomerular filtration rate (eGFR). A history of heart failure

L68Q cystatin C. Expression, cellular transport and turnover of the cystatin C variant forming amyloid in patients with Hereditary Cystatin C Amyloid Angiopathy (HCCAA)

Hereditary cystatin C amyloid angiopathy (HCCAA) is a disorder characterised by multiple strokes in young adults, resulting in paralysis and dementia. The disease is caused by a mutation in the gene coding for the peptidase inhibitor cystatin C. The mutation causes an amino acid substitution Leu68 to Gln in cystatin C (L68Q cystatin C) which results in deposition of the protein in the blood vessel

The effect of two midwives during the second stage of labour to reduce severe perineal trauma (Oneplus): a multicentre, randomised controlled trial in Sweden

BackgroundSevere perineal trauma (SPT) affecting the anal sphincter muscle complex is a serious complication following childbirth, associated with short-term and long-term maternal morbidity. Effective preventive strategies are still scarce. The aim of the Oneplus trial was to test the hypothesis that the presence of a second midwife during the second stage of labour, with the purpose of preventin

Sweden, the United States, and Raoul Wallenberg's Mission to Hungary in 1944

This article provides an in-depth examination of the U.S. government's role in the case of Raoul Wallenberg, the courageous Swedish envoy who died mysteriously in the Soviet Union after being arrested by Soviet occupation forces at the end of World War II for unknown reasons. The article recounts how U.S. officials, particularly the diplomat Herschel V. Johnson, tried to alleviate the plight of Hu

eVisits in the digital era of Swedish primary care

Objective: To evaluate asynchronous digital visits (eVisits) with regard to digital communication, clinical decisionmaking,and subsequent care utilization in the digital era of primary care in Sweden.Methods: A mixed-methods approach was adopted across the various papers in the thesis, with all studiesevaluating the eVisit platform Flow in various clinical contexts.- Paper I was a comparative stud

Technology-adjusted carbon accounting

We present technology-adjusted consumption-based accounting (TCBA) – a measure of shared responsibility for global greenhouse gas emissions. Unlike in conventional consumption-based accounting (CBA), countries are assigned the emission responsibility for the technology they use to produce their exports. This ensures that national emission responsibilities are not driven by differences in export pr

Connecting firm's web scraped textual content to body of science : Utilizing microsoft academic graph hierarchical topic modeling

This paper demonstrates a method to transform and link textual information scraped from companies' websites to the scientific body of knowledge. The method illustrates the benefit of Natural Language Processing (NLP) in creating links between established economic classification systems with novel and agile constructs that new data sources enable. Therefore, we experimented on the European classifi

Reframing Immigrant Resistance : Alliances, Conflicts, and Racialization in Italy

This book focuses on the political participation and grassroots mobilization of immigrants and racialized communities in the European context. Based on extensive data collected in Italy, it explores the role that alliances among pro-immigrant groups play in shaping political participation, asking why and how immigrant activists mobilize in hostile environments, why and how they create alliances wi

Expanding the Protection of Children's Rights towards a Dignified Life: : The Emerging Jurisprudential Developments in the Americas

The Inter-American Court of Human Rights (IACrtHR) has developed in recent years an innovative jurisprudence that has integrated the entity and extension of States’ obligations regarding children’s rights—as established in Article 19 ACHR—through the evolutive, dynamic, and effective interpretation of the American Convention on Human Rights (ACHR). In fact, by acknowledging the existence of an int

CCE in Heterogenous Fixed-T Panels

The present paper shows that the CCE approach of Pesaran (2006) is more useful than commonly appreciated, in that it enables consistent and asymptotically normal estimation of interactive effects models with heterogeneous slope coefficients when the number of time periods, T, is fixed and only the number of cross-sectional units, N, is large.