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This study analyzed Japanese mandible movements using a recently developed technique, the MARRYS helmet [Gudmundsson et al., Interspeech (2024)]. Data were collected from 9 first language and 10 second language (Mandarin Chinese) speakers of Japanese. The speech materials included three sentences composed entirely of /a/ vowels, one neutral sentence and three focus sentences with emphasis on diffe
The European species of the Cheilosia subgen. Neocheilosia Barkalov, 1983 (Diptera,Syrphidae) are revised. The identities of Cheilosia morio (Zetterstedt, 1838) and of its synonyms are reviewed, and C. scanica Ringdahl, 1937 is established as a junior synonym of C. morio. Cheilosia luteicornis (Zetterstedt, 1838) is re-installed as the name for C. morio of authors pro parte, not Zetterstedt. Cheil
The liver is a central metabolic hub, performing vital functions such as bile production, protein, carbohydrate, lipid and drug metabolism, detoxification of xenobiotics, and the synthesis of essential biomolecules for reproduction, and also shows regenerative capability. Several of these functions can be affected by sexual dimorphisms with important consequences. In this study we used high-throug
The use of Earth Observation Data and Machine Learning models to generate gridded micro-level poverty maps has increased in recent years, with several high-profile publications. producing some compelling results. Poverty alleviation remains one of the most critical global challenges. Earth Observation (EO) technologies represent a promising avenue to enhance our ability to address poverty through
Ulnar nerve entrapment at the elbow (UNE) is the second most common compression neuropathy in the upper limb. Immediate return-to-work (RTW) after surgery is seldom possible due to restrictions and recovery demands. We aimed to explore RTW after UNE surgery and investigate factors contributing to variations. A prospective study with patients undergoing primary UNE surgery was conducted. Treatment
The pattern of substitutions at sites in proteins provides invaluable information about their biophysical and functional importance and what selection pressures are acting at individual sites. Amino acid site rates are typically estimated using phenomenological models where sequence variability is described by rate factors that scale the overall substitution rate in a protein to sites. In this stu
We resolve the multiple images of the binary-lens microlensing event ASASSN-22av using the GRAVITY instrument of the Very Large Telescope Interferometer (VLTI). The light curves show weak binary-lens perturbations, complicating the analysis, but the joint modeling with the VLTI data breaks several degeneracies, arriving at a strongly favored solution. Thanks to precise measurements of the angular
Hybrid perovskites are interesting optoelectronic materials. The perovskite ABX3 structure offers a vast compositional space, and we have identified over 300 perovskite ions. This flexibility enables tuneable properties and has significantly contributed to the success of perovskite optoelectronics. However, this diversity also leads to confusion, ambiguity, and inconsistencies causing challenges f
Peripheral nerve tumours, most commonly schwannomas and neurofibromas, might present significant challenges by eliciting physical symptoms and emotional distress. We aimed to explore patients’ expectations, perceptions, and experiences regarding their diagnosis and the surgical treatment of a nerve tumour in the upper limb. Fourteen adults (10 women, 4 men; age range 35–85) from two Swedish hand s
Context. Hot Jupiters (HJs) with close-by planetary companions are rare, with only a handful of them having been discovered so far. This could be due to their suggested dynamical histories, which lead to the possible ejection of other planets. TOI-2109 b is special in this regard because it is the HJ with the closest relative separation from its host star, being separated by less than 2.3 stellar
Background: Patients with diabetes admitted to emergency care face a higher risk of complications, including prolonged hospital stays, admissions to the intensive care unit and mortality. Aim: To develop a machine learning (ML) model to predict 30-day mortality in patients with diabetes admitted to the emergency department (ED). Design and setting: A cohort study utilizing data from all nine ED’s
Purpose: There are limited data to show how sex impacts the early clinical course of patients with Hirschsprung disease (HSCR). This study aimed to explore potential sex related disparities in the preoperative, surgical, and early postoperative course of HSCR patients. Methods: This retrospective study analyzed data of HSCR patients who underwent pull-through surgery at pediatric surgery centers i
Objectives: Gram-positive anaerobic cocci are opportunistic pathogens that exploit immune suppression or tissue injury to establish infections. Atopobium spp. are clinically relevant, being linked to bacterial vaginosis, abdominal wounds, pelvic abscesses, and dental infections. While clinical reports describe the involvement in detrimental host conditions, in-depth knowledge is missing to underst
Background: The Autism- Tics, ADHD and other Comorbidities inventory (A-TAC) has been validated in epidemiological data. However, validation against clinical diagnostic assessments in a population-based sample has been lacking, limiting the implications for clinical practice, clinical research and public health decisions. Methods: Study participants were recruited from the longitudinal Child and A
Chaperone proteins are essential for maintaining proteostasis. Their main role is to assist with the folding of other proteins and to prevent the aggregation of misfolded proteins. The molecular chaperone DNAJB6b efficiently suppresses amyloid formation of several peptides. This activity may rely on the same physicochemical properties as those driving chaperone self-assembly into large micellar-li
Dental caries is the most common oral disease that causes demineralization of the enamel and later of the dentin. Depth-wise assessment of the demineralization process could be used to help in treatment planning. In this study, we aimed to provide baseline information for the development of a Raman probe by characterizing the mineral composition of the dental tissues from large composition maps (6
The influence of joint degeneration on the biomechanical properties of calcified cartilage and subchondral bone plate at the osteochondral junction is relatively unknown. Common experimental difficulties include accessibility to and visualization of the osteochondral junction, application of mechanical testing at the appropriate length scale, and availability of tissue that provides a consistent r
Background: Cystic fibrosis (CF)-related diabetes (CFRD) is the most common extrapulmonary complication in CF. CFRD is associated with low lung function, but the underlying mechanisms are poorly understood. The aim of the present study was to compare airway inflammation and the airway proteome in people with CF (pwCF) with and without CFRD.Methods: Sputum samples from pwCF were analysed for neutro
Leucine-rich repeat containing 15 (LRRC15) has emerged as an attractive biomarker and target for cancer therapy. Transforming growth factor-β (TGFβ) induces the expression of this plasma membrane protein specifically in aggressive and treatment resistant tumor cells derived from mesenchymal stem cells, with minimal expression observed in non-neoplastic tissues. We have developed a humanized monocl
