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Glial cell line-derived neurotrophic factor (GDNF) has been shown to counteract seizures when overexpressed or delivered into the brain in various animal models of epileptogenesis or chronic epilepsy. The mechanisms underlying this effect have not been investigated. We here demonstrate for the first time that GDNF enhances GABAergic inhibitory drive onto mouse pyramidal neurons by modulating posts

Denna antologi är ett arbete som varenda människa med något intresse för mänsklighet och samhällsfrågor måste läsa och reflektera över. De samlade berättelserna, undersökningarna och rapporterna som presenteras i antologin utgör en tvärvetenskaplig samtidsanalys över det svenska myndighetssystemet och dess inverkan på människoöden, kanske för generationer framåt.De samlade berättelserna, undersökningarna och rapporterna som presenteras i antologin utgör en tvärvetenskaplig samtidsanalys över det svenska myndighetssystemet och dess inverkan på människoöden, kanske för generationer framåt.

Recension av Gellert Hardi-Kovacs, Hemligast av alla – C-byrån. Berättelsen om Sveriges hemliga underrättelse under andra världskriget.

States in the Global South are facing a double challenge of achieving socio-economic development while adapting to climate change impacts. This study maps to what extent Small Island Developing States (SIDS) manage to meet the Sustainable Development Goals (SDGs). The SIDS are at the front line of climate change and while they share numerous challenges, the SIDS are also a heterogeneous group cont

Localization and mapping is the foundational technology for augmented reality (AR) that enables sharing and persistence of digital content in the real world. While significant progress has been made, researchers are still mostly driven by unrealistic benchmarks not representative of real-world AR scenarios. In particular, benchmarks are often based on small-scale datasets with low scene diversity,

This article uses the Polish case of Wrocław (formerly Breslau), a city burdened by memories of war and forced displacement, to show the dynamics between hegemonic memories, dominant memories and countermemories. After the fall of communism, the city changed the previous nationalist-communist narrative of its past by institutionalizing a new official narrative that promotes cosmopolitan memory. Th

In 2019 Olga Tokarczuk, an outstanding Polish writer received Nobel Prize in literature. The prize appeared as a culmination of her growing popularity outside Poland, including Sweden. In our article we attempt to trace Tokarczuk´s pathway to Nobel Prize, through studying her reception in Sweden. Already in 2005 the first translations of her books appeared in Sweden, with enthusiastic reviews. Her

Abstract in GermanDer folgende Beitrag veranschaulicht bedeutende kulturelle Entwicklungen in der Litauischen SSR der Stalin- und der Chruščev-Ära, die gleichsam deutlich machen, dass die Sowjetisierung in einem Wechselverhältnis mit der litauischen Nationsbildung stand. Mit dem Fokus auf herausragende Kulturfunktionäre demonstriert der Aufsatz den Ausbau der Kulturstrukturen, die Mobilisierung loAbstract in PolishCelem badania było wykazanie napiętego stosunku między procesami sowietyzacji i tworzenia się litewskiego narodu. Do ich zobrazowania wybrałam kulturowy rozwój scenicznego folkloru i kina, które skupiały się wokół wybitnych funkcjonariuszy kultury epoki Stalina i Chruszczowa. Za pomocą instytucjonalizacji, mobilizacji elity, jak i konkretnej pracy funkcjonariuszy przedstawiono, w

In the 1960s, Soviet Lithuania witnessed the rise of an intensied interest in paganism. Aiming to diminish the infuence of the Roman Catholic Church, the Communist Party promoted Lithuanian pre-Christian customs and rituals that, in turn, not only became a successful instrument against Catholicism but also an effective stimulus of nationalism. Arising within the framework of academic touristic c

Objectives: The credit market has expanded rapidly, increasing the risk of over-indebtedness among those who lack secure employment or adequate income, an issue of concern in the COVID-19 aftermath. We investigated the role of over-indebtedness for developing poor mental health, and whether this impact is modified by age, gender, educational level or being in precarious employment.Methods: This isOBJECTIVES: The credit market has expanded rapidly, increasing the risk of over-indebtedness among those who lack secure employment or adequate income, an issue of concern in the COVID-19 aftermath. We investigated the role of over-indebtedness for developing poor mental health, and whether this impact is modified by age, gender, educational level or being in precarious employment.METHODS: This is

In this paper, the most important results are presented and discussed from a multiyear interdisciplinary study directed toward the identification of the most suitable glass/polymer composite systems with the highest resistance to brittle fracture for high voltage composite insulator applications. Several unidirectional glass/polymer composite systems, commonly used in composite insulators, based e

An improved version of a brittle fracture model based on the formation of nitric acid in service through corona discharges, ozone, and moisture, is presented and used to explain different modes of brittle fracture. Throughout the work, the insulators are referred to as nonceramic insulators (NCIs). The information given is expected to help the insulator manufacturers and users design, manufacture,