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National EQ-5D tariffs and quality-adjusted life-year estimation: comparison of UK, US and Danish utilities in south Swedish rheumatoid arthritis patients.

OBJECTIVE: To study how the choice of national EQ-5D tariff may affect utility and incremental quality-adjusted life-year (QALY) estimates. METHODS: South Swedish rheumatoid arthritis patients in an observational study, starting and continuing anti-tumour necrosis factor (TNF) monotherapy (n=54) or anti-TNF plus methotrexate (n=215) for 1 year during May 2002 to April 2009, were included. EQ-5D q

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Abstract in German Das Messen von Beschleunigungen und Höhen während einer Achterbahnfahrt bietet die Möglichkeit, den Physikunterricht anwendungsbezogen zu gestalten. Dieser Ansatz erlaubt einen erlebnisorientierten Zugang speziell im Bereich der oftmals als langweilig empfundenen Mechanik. Das Beispiel der Achterbahn Kanonen in Göteborg demonstriert die vielen Möglichkeiten der Datenauswertung.

Combustion Engine Characterization and Development by Means of Laser Diagnostics

Planar laser induced fluorescence (LIF) has been utilized for two-dimensional imaging in combustion environments. By using tracer LIF the fuel distribution prior to ignition has been monitored in a GDI-engine. The results obtained were used to determine the influence from various engine parameters such as nozzle type, spray angle, duration of injection, start of injection, piston shape, etc. Two f

Integration of system dynamics modelling with descriptive process modelling and goal-oriented measurement

One of the obstacles that seem to impede a more frequent application of the modelling and simulation approach system dynamics (SD) in the software engineering community is the lack of well-defined and repeatable procedures for generating or using information that (a) stems from real industrial software development practice and (b) is suitable for SD model building. This problem can be resolved, at

Myogenic Reprogramming of Bone Marrow Derived Cells in a WDmd Deficient Mouse Model.

Lack of expression of dystrophin leads to degeneration of muscle fibers and infiltration of connective and adipose tissue. Cell transplantation therapy has been proposed as a treatment for intractable muscle degenerative disorders. Several reports have demonstrated the ability of bone-marrow derived cells (BMDC) to contribute to non-haematopoietic tissues including epithelium, heart, liver, skelet

Effects of Opioids on Breathlessness and Exercise Capacity in Chronic Obstructive Pulmonary Disease: A Systematic Review.

Patients with chronic obstructive pulmonary disease commonly suffer from breathlessness, deconditioning, and reduced health-related quality of life (HRQL) despite best medical management. Opioids may relieve breathlessness at rest and on exertion in COPD. We aimed to estimate the efficacy and safety of opioids on refractory breathlessness, exercise capacity, and HRQL in COPD.

Respondent-driven sampling in a syringe exchange setting.

Aims: Respondent-driven sampling is a research technique, new to the Scandinavian setting, used in hard-to-reach populations, such as subjects at risk for HIV, including drug users. This study aimed to evaluate the use of respondent-driven sampling originating from syringe exchange clients, as a method to identify 'hidden' drug users without treatment or social service contact. Methods: Nine heroi

Orthostatic hypotension predicts all-cause mortality and coronary events in middle-aged individuals (The Malmo Preventive Project).

Aims Orthostatic hypotension (OH) has been linked to increased mortality and incidence of cardiovascular disease in various risk groups, but determinants and consequences of OH in the general population are poorly studied. Methods and results Prospective data of the Swedish 'Malmö Preventive Project' (n = 33 346, 67.3% men, mean age 45.7 +/- 7.4 years, mean follow-up 22.7 +/- 6.0 years) were analy

Klagomålshantering – ett led i att höja kvaliteten eller prat om bagateller?

På kommunernas hemsidor uppmanas äldre att klaga och komma med synpunkter. Klagomål beskrivs som ett värdefullt led för att förbättra verksamheten. Men hanteringen är rörig och klagomålen bagatelliseras av ansvariga chefer, visar forskning från Hälsohögskolan i Jönköping. ”De klagar mest på småsaker, att hemtjänsten inte kommer ibland och så där”, sade en av de socialchefer jag intervjuade i mitt