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Copy number analysis indicates monoclonal origin of lethal metastatic prostate cancer.

Many studies have shown that primary prostate cancers are multifocal and are composed of multiple genetically distinct cancer cell clones. Whether or not multiclonal primary prostate cancers typically give rise to multiclonal or monoclonal prostate cancer metastases is largely unknown, although studies at single chromosomal loci are consistent with the latter case. Here we show through a high-reso

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To dig and to write: Author questions the concept of basic archive reports and argues that the pyramidal working structure of archaeology must be demolished. Drawings by Inger Karlberg.

Analytical Use of Proton-Induced X-Ray Emission

Proton-induced X-ray emission, PIXE, is capable of simultaneous quantitative determination of 10-15 elements. An introduction to the physical properties of the method is given and detection limits are shown for a routine analysis of a thin aerosol sample. Examples of applications to both thick and thin samples are presented. Human tooth dentine is analysed for lead, with simple sample preparation,

Molecular correlates for maximal oxygen uptake (VO2max) and type 1 fibers.

Maximal oxygen uptake (VO2max) and the amount of type 1 fibers are interrelated but the underlying unifying molecular mechanisms are poorly understood. To explore these mechanisms we related gene expression profiles in skeletal muscle biopsies of 43 age-matched men from published datasets with VO2max and amount of type 1 fibers and replicated some of the findings in muscle biopsies from 154 young

Så blev kapitalismen senil

Arena har mött Michael Hardt och Samir Amin, två av världens mest kända systemkritiker, i ett samtal om framtiden.

Awareness among nurses about reporting of adverse drug reactions in Sweden.

BACKGROUND: The purpose of this study was to investigate awareness among nurses regarding their new role as reporters of adverse drug reactions in Sweden and factors that may influence reporting by nurses. METHODS: In 2007, all nurses were included in the adverse drug reaction reporting scheme in Sweden. A questionnaire was sent to 753 randomly selected nurses in September 2010. RESULTS: Of

Lektioner i 7F

Allan Friis tecknar bilden av en absurd institution som hos många elever förmår skapa motvilja till och med mot något så positivt som kunskap.