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Disruption of a GATA1-binding motif upstream of XG/PBDX abolishes Xga expression and resolves the Xg blood group system
The Xga blood group is differentially expressed on erythrocytes from men and women. The underlying gene, PBDX, was identified in 1994, but the molecular background for Xga expression remains undefined. This gene, now designated XG, partly resides in pseudoautosomal region 1 and encodes a protein of unknown function from the X chromosome. By comparing calculated Xga allele frequencies in different
Filamentary anemometry using femtosecond laser-extended electric discharge - FALED
We demonstrate a non-contact spatiotemporally resolved comprehensive method for gas flow velocity field measurement: Filamentary Anemometry using femtosecond Laser-extended Electric Discharge (FALED). A faint thin plasma channel was generated in ambient air by focusing an 800-nm laser beam of 45 fs, which was used to ignite a pulsed electric discharge between two electrodes separated over 10 mm. T
Att göra en klassiker: om formvärldens kändisar och hur de skapas
Textbidrag till utställningsbroschyr i anslutning till den tillfälliga utställningen IKEA Hacked. Våra produkter. Dina idéer. på IKEA Museum i Älmhult som pågår mellan 28 april 2018 och 24 mars 2019.
Identification of intrinsic regulators in normal and malignant human hematopoiesis. An RNA-interference approach.
Bildandet av blodceller, hematopoesen, utgår från ett litet antal av de så kallade hematopoetiska stamceller som sitter i vår benmärg. Dessa celler har förmågan att ge upphov till alla mogna blodcellstyper av de tre hematopoetiska linjerna, samtidigt som de genom celldelning bibehåller sin egna mängd. Det har uppskattats att vi endast har några tusen hematopoetiska stamceller, men trots deras rela
Capturing seniors’ requirements for assistive robots by the use of attention cards
Abstract in UndeterminedIn this paper we describe and reflect upon a novel methodology using attention cards to facilitate communication, concentration and creativity in a user requirement workshop with seniors. Previous research indicates that seniors tend to lose focus and start cross talking during workshops, which results in broad and shallow findings. However, our findings indicate that the u
Men Are Vulnerable Too : Analysing the Self-presentation of Indian Men's Rights Activist Online Network
Review of de Groot (ed.) Uralic Essive and the Expression of Impermanent State
CFTR is involved in the regulation of glucagon secretion in human and rodent alpha cells
Glucagon is the main counterregulatory hormone in the body. Still, the mechanism involved in the regulation of glucagon secretion from pancreatic alpha cells remains elusive. Dysregulated glucagon secretion is common in patients with Cystic Fibrosis (CF) that develop CF related diabetes (CFRD). CF is caused by a mutation in the Cl- channel Cystic fibrosis transmembrane conductance regulator (CFTR)
Specific Cation Effects on SCN– in Bulk Solution and at the Air−Water Interface
The large and sparsely hydrated thiocyanate anion, SCN–, plays a prominent role in the study of specific ion effects in biological, colloid, and atmospheric chemistry due to its extreme position in the Hofmeister series. Using atomistic modeling of aqueous SCN– solutions, we provide novel insight at the molecular scale into the experimentally observed differences in ion pairing, clustering, reorie
Micropatterned Carbon-on-Quartz Electrode Chips for Photocurrent Generation from Thylakoid Membranes
Harvesting the energy generated by photosynthetic organisms through light-dependent reactions is a significant step toward a sustainable future energy supply. Thylakoid membranes are the site of photosynthesis, and thus particularly suited for developing photo-bioelectrochemical cells. Novel electrode materials and geometries could potentially improve the efficiency of energy harvesting using thyl
Small and Large, Charged Molecules in Solution and at Interfaces
Växelverkningar mellan små och stora molekyler har konsekvenser för reaktioner som kemister utför i sina provrör, lika mycket som för de livsnödvändiga reaktionerna som sker i vår kropp och våra celler. Förståelsen av dessa växelverkningar är nyckeln till att kunna utnyttja dem till vår fördel, till exempel i industriella processer eller i utveckling av mediciner. För att uppnå detta kan man utförThe influence of small and large, charged molecules on the properties of aqueous interfaces has important implications in chemistry, biology, and medicine. For example, at the surface of marine aerosols, the presence of halide anions and tropospheric gases gives way to multiphase chemical reactions affecting climate and air quality. In this Thesis, we investigate three different systems and phenom
Har EAN-kodens placering någon betydelse för arbetsbelastningen vid kassaarbete? : Rapport nr 2
Att arbeta som kassör vid utgångskassa anses vara ergonomiskt belastande. En vanlig uppfattning är att om kunden lägger varorna en och en på bandet samt vänder EAN-koden mot scannern, så minskar kassörens arbetsbelastning.Arbets- och miljömedicin Syd har i samarbete med Handelsanställdas Förbund genomfört en pilotstudie i kassaarbete vid scanning av varor. Pilotstudiens syfte är att undersöka om d
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On 21 April 2018 Dutch government sent a reaction on the 2017 evaluations of the gift deduction and the charity rules to Dutch Parliament. Starting point of the reaction is that the gift deduction and the charity rules will be continued. However, government wants to improve the workability and enforceability. This article discusses the most important suggestions for changes of the government and t
Machines and Energy. Energy Capital ratios in Europe and Latin America 1875 - 1970
The relationship between energy and capital is one of the most important aspects of modern economic growth. Machines need energy to produce all the goods we enjoy; energy would be far less useful for humankind in absence of machines. However, the great majority of the economic models do not take into account the elasticities of substitution (or complementaries) between these two main variables. Ac
Svälten som fick många att köpa Amerikabiljett
Recension av Magnus Västerbro, "Svälten"
Bör kunder vända streckkoden rätt i kassan?
EAN-kodens betydelse vid scanning av varorAtt arbeta som kassör vid utgångskassa anses vara ergonomiskt belastande. En vanlig uppfattning är att om kunden lägger varorna en och en på bandet samt vänder EAN-koden mot scannern, så minskar kassörens arbetsbelastning.Arbets- och miljömedicin Syd har i samarbete med Handelsanställdas Förbund genomfört en pilotstudie i kassaarbete vid scanning av varor.
Studies of Ligands and Receptors Regulating Acute Myeloid Leukemia
Acute myeloid leukemia (AML) is the most common leukemia in adults and is coupled to a poor prognosis, with a five-year overall survival of around 20% and a high risk of relapse. In AML, immature myeloid cells accumulate rapidly in the bone marrow impairing normal blood cell development. Current treatments fail to eradicate the leukemia stem cells, which is a self-renewing population of leukemia c
Bitcoding the brain. Integration and organization of massive parallel neuronal data.
Prevention of type 2 diabetes and poor mental health amongst immigrants from the Middle-East to Sweden
Background: Type 2 diabetes (T2D) and poor mental health are two major public health concerns in Europe. Ethnicity is identified as a risk marker for both conditions. Middle-Eastern immigrants represent the largest group of non-European immigrants in Sweden and are at increased risk for T2D. In clinical trials, lifestyle interventions focusing on physical activity and healthy diet have been shown
