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Panel 6 : Vaccines

Objective: To review the literature on progress regarding (1) effectiveness of vaccines for prevention of otitis media (OM) and (2) development of vaccine antigens for OM bacterial and viral pathogens. Data Sources: PubMed database of the National Library of Science. Review Methods: We performed literature searches in PubMed for OM pathogens and candidate vaccine antigens, and we restricted the se

Testing construct independence in the Short Dark Triad using Item Response Theory

The Dark Triad (i.e., Machiavellianism, narcissism and psychopathy) is a popular construct for describing socially aversive personality traits. In recent years, the Short Dark Triad (SD3; Jones & Paulhus, 2014) has become a popular measure for assessing the Dark Triad constructs. However, recent research has called the supposed dissimilarity between the Dark Triad constructs into question. In

Diagnosis, Symptoms, and Outcomes of Hirschsprung's Disease from the Perspective of Gender

Background/Aim. Hirschsprung's disease (HD) has a skewed gender distribution, with a female to male ratio of 1 : 4. This study aims to examine differences between boys and girls with HD regarding preoperative features and postoperative treatment and outcome. Method. The first part of the study was conducted as a retrospective review of all HD patients who underwent transanal endorectal pull-throug

Panel 8 : Report on Recent Advances in Molecular and Cellular Biochemistry

Objectives: To update the medical literature on recent cellular and molecular advances in otitis media disease models with a principal focus on developments in the past 5 years. We also aim to explain recent translational advances in cellular and molecular biology that have influenced our understanding and management of otitis media. Data Sources: PubMed-indexed peer-reviewed articles. Review Meth

Tumour necrosis factor-α/etanercept complexes in serum predict long-term efficacy of etanercept treatment in seronegative rheumatoid arthritis

Objective: To study whether serum levels of tumour necrosis factor-α (TNF-α), free or bound to etanercept, in biological-naïve adults with rheumatoid arthritis (RA) could predict the long-term efficacy of etanercept, measured as drug survival. Method: We identified 145 biological-naïve patients with RA starting treatment with etanercept at the Department of Rheumatology, Skåne University Hospital

Ozonation efficiency in removing organic micro pollutants from wastewater with respect to hydraulic loading rates and different wastewaters

Organic micro pollutants can be removed from water by ozonation. In this article we studied the performance of ozonation under real life conditions and compared results of the same ozonation pilot plant installed at different wastewater treatment plants (WWTPs) thus operating with different waters. The comparability of the removal and reaction rate constants from one waste water treatment plant we

Spatiotemporal Dynamics of the Cortical Responses Induced by a Prolonged Tactile Stimulation of the Human Fingertips

The sense of touch is fundamental for daily behavior. The aim of this work is to understand the neural network responsible for touch processing during a prolonged tactile stimulation, delivered by means of a mechatronic platform by passively sliding a ridged surface under the subject’s fingertip while recording the electroencephalogram (EEG). We then analyzed: (i) the temporal features of the Soma

The landscape of W± and Z bosons produced in pp collisions up to LHC energies

We consider a selection of recent experimental results on electroweak W±,Z gauge boson production in pp collisions at BNL RHIC and CERN LHC energies in comparison to prediction of perturbative QCD calculations based on different sets of NLO parton distribution functions including the statistical PDF model known from fits to the DIS data. We show that the current statistical PDF parametrization (fi

NutsFor a process-oriented model to simulate nutrient and isotope tracer cycling in forest ecosystems

We developed a process-oriented model called NutsFor that simulates nutrient cycling of major cations (Ca, Mg, K, Al, NH4, Na) and anions (NO3, SO4, Cl) and the stable isotope tracers for each of the respective elements at the scale of an ecosystem (isotopic fractionation are not simulated). We tested the ability of NutsFor to reproduce major element and stable isotope tracer (26Mg and 44Ca) cycli

Heat transfer and turbulent flow characteristics over pocket cavity in the junction part of an outlet guide vane in a gas turbine

A pocket cavity is generated when the Low Pressure Turbine (LPT) is connected to the Outlet Guide Vane (OGV) in the rear part of a gas turbine engine due to the different conjugate diameters. This kind of pocket cavities, due to the high Reynolds number and the specific shapes, are hardly investigated in previous researches. The heat transfer distribution and fluid flow over the pocket cavity have

Nature of three episodes of Paleoproterozoic magmatism (2180 Ma, 2115 Ma and 1890 Ma) in the Liaoji belt, North China with implications for tectonic evolution

Three episodes of Paleoproterozoic magmatism with distinctively different nature in the Liaoji belt of the Eastern North China Craton are discussed here: the 2200–2140 Ma Liaoji A-type granites, the 2160–2110 Ma Haicheng mafic sills and the ∼1890 Ma Qingchengzi I-type granites. The Mafeng monzogranitic pluton, representative of the Liaoji A-type granites, gives a SIMS U-Pb zircon age of 2181 ± 6 M

Wavy Surface Cathode Gas Flow Channel Effects on Transport Processes in a Proton Exchange Membrane Fuel Cell

The flow field design of current collectors is a significant issue, which greatly affects the mass transport processes of reactants/products inside fuel cells. Especially for proton exchange membrane (PEM) fuel cells, an appropriate flow field design is very important due to the water balance problem. In this paper, a wavy surface is employed at the cathode flow channel to improve the oxygen mass

Seasonal Decline in Clutch Size of the Marsh Tit (Parus palustris) in Relation to Date-Specific Survival of Offspring

This paper documents and evaluates seasonal trends in reproductive performance in the Marsh Tit (Parus palustris) in southern Sweden. Clutch size decreased for nests started later in the season. This pattern held true both for second-year and older females when analyzed separately. Individual females adjusted clutch size in relation to the relative time of season they produced a clutch a particula

Intrasexual competition among polygynously mated female starlings (Sturnus vulgaris)

In southern Sweden, the starling (Sturnus vulgaris) has a variable mating system with some males mating monogamously and others attracting several females. Mating status affected the reproductive success of females: monogamous and primary females laid larger clutches and fledged more and heavier young than secondary females. This pattern was explained by female competition for male help, with the

Development and maintenance of nestling size hierarchies in the European starling (Sturnus vulgaris)

In this paper we show that nestling mass hierarchies in the European Starling (Sturnus vulgaris) are due to asynchronous hatching. The parents may, by starting to incubate the day the penultimate egg is laid, or earlier, affect the degree of hatching asynchrony and thereby the nestling weight hierarchy. Intra-clutch variation in egg size had no effect on nestling weight hierarchies, explaining onl

Parent-offspring conflict over reproductive efforts: Variations upon a theme by Charnov

A novel formulation of the theory of parent-offspring conflict is proposed. The basis of this formulation is an application of traditional life-history theory in combination with simple genetic arguments. The advanatage with this approach is conceptual, and the formulation is not in variance with earlier studies in the area. Parent-offspring conflict is, in our forumlation, not seen as a conflict

Adaptive significance of egg size in the European Starling: experimental tests

Reproductive success in relation to egg size was studied in European Starlings (Sturnus vulgaris) by swapping whole clutches between nests at the start of the incubation period. Egg size did not reflect parental quality as no measure of reproductive success was correlated with the foster mothers' mean egg size. There was a significant positive relationship between the mean size of the cross-foster

Paternal care in the European starling, Sturnus vulgaris: incubation

In polygynous passerines, males of some species provide food for their nestlings, but male incubation seems to be rare. In the European starling both the mating system and the extent to which males help with incubation vary. This enabled the relationship between mating system and male incubation to be investigated. The extent to which males provided care to a particular nest depended on mating sta

Experimental demonstration of a trade-off between mate attraction and paternal care

Males should invest in mate attraction, mate guarding and paternal care in relation to the marginal fitness value of each of those behaviours. Since time and energy are limited, trade-offs between these activities are expected. This study demonstrates that monogamous male European starlings (Sturnus vulgaris) decrease their paternal effort in response to increased opportunities to attract addition

Heritability of nestling growth in cross-fostered European Starlings, Sturnus vulgaris

In altricial birds, growth rates and nestling morphology vary between broods. For natural selection to produce evolutionary change in these variables, there must exist heritable variation. Since nestling traits are not any longer present in parents, traditional offspring-parent regressions cannot estimate heritabilities of these. In this study, a partial cross-fostering experiment was performed, w