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Experimental porcine models of retinal ischemia

Popular Abstract in Swedish Näthinnan (retina) ligger längst bak i ögat och fungerar som filmen i en kamera. Stavar och tappar registrerar ljus och signalen går via nerver till syncentra i hjärnan. Blodkärl löper genom näthinnan och förser cellerna med syre och näring samt transporterar bort slaggprodukter. Kärlsjukdomar, som t.ex. diabetes, blodproppar i näthinnan till följd av åderförkalkning ocRetinal ischaemia resulting from e.g. diabetes, vein thrombosis or arterial occlusion, is one of the major causes of visual impairment and blindness. Although new methods of treatment are being developed, there is still a need for more effective pharmacological forms of treatment. The aim of this work was to develop an appropriate animal model of retinal ischaemia in which the intracellular signal

Changing pattern in the prescription of biological treatment in rheumatoid arthritis. A 7-year follow-up of 1839 patients in southern Sweden

Objective: To study prescription patterns of biological treatment in rheumatoid arthritis ( RA) patients in southern Sweden, a region with no formal or economic restrictions for the use of biological treatment in rheumatological diseases. Specifically, we studied conformity with the national Swedish guidelines for biologics in RA. Methods: Rheumatologists in southern Sweden contribute to a volunta

Mannen som gifte sig med en bäver : Ett omöjligt äktenskap?

I kanadensiska mi'kmaqberättelser, vilka nedtecknades under tiden som gruppen levde som jägare och samlare, finna flera skildringar av djur som flitiga agenter. Det finns till och med berättelser om äktenskap mellan människor och djur som dock alltid slutar olyckligt. Hur ska dessa berättelser läsas? Som nonsens eller säger de något om gränser och förhållningssätt till det vi i väst dikotomiserat

Mapping the d-d Excited-State Manifolds of Transition Metal beta-Diiminato-Imido Complexes. Comparison of Density Functional Theory and CASPT2 Energetics

Trigonal-planar, middle transition metal diiminato-imido complexes do not exhibit high-spin states, as might be naively expected on the basis of their low coordination numbers. Instead, the known Fe(III), Co(III), and Ni(III) complexes exhibit S = (3)/(2), S = 0, and S = (1)/(2), ground states, respectively. Kohn-Sham DFT calculations have provided a basic molecular orbital picture of these compou

Enantioselective synthesis of anti-beta-amido-alpha-hydroxy esters via asymmetric transfer hydrogenation coupled with dynamic kinetic resolution

The asymmetric transfer hydrogenation of beta-amido-alpha-keto esters providing the corresponding anti-beta-amido-alpha-hydroxy esters via dynamic kinetic resolution is reported. The use of a commercially available, or simply prepared, chiral ruthenium catalyst results in good yields as well as high diastereoselectivities and enantioselectivities. (C) 2013 Elsevier Ltd. All rights reserved.

Breastfeeding of preterm infants. Associated factors in infants, mothers, and clinical practice.

Abstract in Danish Amning har sundhedsmæssige fordele for mor og barn og mere udtalte fordele for præmature børn, men udenlandske undersøgelser viser, at færre præmature børn påbegynder amning, og færre præmature børn ammes i 4 og 6 måneder sammenlignet med mature børn. Der findes ikke danske undersøgelser om andelen af præmature børn, som påbegynder amning, men en dansk undersøgelse viser, at 60 Breastfeeding has even more pronounced health benefits for preterm infants than for full-term infants, but preterm infants are less breastfed. There is no consensus in Danish neonatal intensive care units (NICUs) about which clinical methods facilitate breastfeeding. Skin-to-skin contact between infant and parent is the first step in the breastfeeding process for preterm infants, but studies of to

An improved capillary model for describing the microstructure characteristics, fluid hydrodynamics and breakthrough performance of proteins in cryogel beds.

A capillary-based model modified for characterization of monolithic cryogels is presented with key parameters like the pore size distribution, the tortuosity and the skeleton thickness employed for describing the porous structure characteristics of a cryogel matrix. Laminar flow, liquid dispersion and mass transfer in each capillary are considered and the model is solved numerically by the finite

Mechanisms and Consequences of Chromosomal Instability in Malignant tumours

In this thesis, telomere deficiency with subsequent anaphase bridging was found to be associated with chromosomal instability in established colorectal cancer cell lines and in Wilms tumour. In colorectal cancer cell lines, anaphase bridging was observed to generate both numerical and structural chromosomal aberrations and was also associated with the presence of multipolar mitoses. In contrast to

Diabetes, healthcare cost and loss of productivity in Sweden 1987 and 2005-a register-based approach

Aim The aim of this study was to estimate healthcare cost and productivity losses as a result of diabetes and diabetes-related chronic complications in Sweden in 1987 and 2005. Research design and methods Published estimates on relative risks and Swedish age-specific diabetes-prevalence rates were used to calculate the proportions of diabetes-related chronic complications that are attributable to

Promises, Rights and Claims

Abstract in Undetermined The paper argues that promise rights presuppose independently existing (if not pre-existing) claims. The argument relies on the Bifurcation Thesis, according to which all claims, and all rights, can be exhaustively divided into two categories: capacity based and exercise based.

Multi-strange baryon production at mid-rapidity in Pb-Pb collisions at root s(NN)=2.76 TeV

The production of Xi(-) and Omega(-) baryons and their anti-particles in Pb-Pb collisions root s(NN) = 2.76 TeV has been measured using the ALICE detector. The transverse momentum spectra at mid-rapidity (vertical bar y vertical bar < 0.5) for charged Xi and Omega hyperons have been studied in the range 0.6 < P-T < 8.0 GeV/c and 1.2 < p(T) < 7.0 GeV/c, respectively, and in several centrality inter

Accuracy of advanced versus strictly conventional 12-lead ECG for detection and screening of coronary artery disease, left ventricular hypertrophy and left ventricular systolic dysfunction

Background: Resting conventional 12-lead ECG has low sensitivity for detection of coronary artery disease (CAD) and left ventricular hypertrophy (LVH) and low positive predictive value (PPV) for prediction of left ventricular systolic dysfunction (LVSD). We hypothesized that a similar to 5-min resting 12-lead advanced ECG test ("A-ECG") that combined results from both the advanced and conventional

Efficient Bounding of Displaced Bézier Patches

In this paper, we present a new approach to conservative bounding of displaced Bézier patches. These surfaces are expected to be a common use case for tessellation in interactive and real-time rendering. Our algorithm combines efficient normal bounding techniques, min-max mipmap hierarchies and oriented bounding boxes. This results in substantially faster convergence for the bounding volumes of di