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To estimate the relationship between heredity and proband's age/parity on the risk of undergoing surgery for pelvic organ prolapse and stress incontinence. Study design: Swedish population based study. Data from two national Swedish registers were used: the Hospital Discharge Register, National Board of Health and Welfare, containing information on all in-patient surgical procedures on Swedish hos
The adsorption of p-aminobenzoic acid (pABA) on the anatase TiO2(101) surface has been investigated using synchrotron radiation photoelectron spectroscopy, near edge X-ray absorption fine structure (NEXAFS) spectroscopy, and density functional theory (DFT). Photoelectron spectroscopy indicates that the molecule is adsorbed in a bidentate mode through the carboxyl group following deprotonation. NEX
An overview is given of the types of energy converters considered by this symposium: systems that make use of nanoscale phenomena and nanotechnology to achieve higher conversion efficiency, to achieve qualitatively enhanced performance, or to access new energy resources. The focus is on general concepts and principles, and approaches used by several nanoscale energy converters are identified.
Despite the extensive use of retinal photocoagulation for ischaemia and vascular leakage in retinal vascular disease, the molecular mechanisms behind its clinical beneficial effects are still poorly understood. One important target of laser irradiation is the retinal pigment epithelium (RPE). In this study, we aimed at identifying the isolated effects of photocoagulation of RPE at both the mRNA an
Studies increasingly apply a multidimensional proximity framework in the analysis of collaborations between actors. This article explores the influence of collaboration motives on the desired proximity characteristics of partnerships in innovation projects based on 50 interviews with representatives from Danish cleantech firms. How search criteria along proximity dimensions differ depends on the p
A continuum model of paperboard material possessing a high degree of anisotropy is established. To handle the anisotropy, three vectors are introduced which phenomenologically represent the preferred directions of the material. The in-plane director vectors deform as line segments and the out-of-plane direction deforms as a normal vector. This allows for a decoupling of the in-plane and the out-of
Objective We describe disease activity, damage, and the accrual of key autoantibodies in an inception systemic lupus erythematosus (SLE) cohort. Methods. The Systemic Lupus International Collaborating Clinics (SLICC) International Research Network, comprising 27 centers from 11 countries, has followed an inception cohort of SLE patients yearly according to a standardized protocol. Of these patient
The aim of this paper is to extend to Hom-algebra structures the theory of 1-parameter formal deformations of algebras which was introduced by Gerstenhaber for associative algebras and extended to Lie algebras by Nijenhuis and Richardson. In this paper, formal deformations of Hom-associative and Hom-Lie algebras are studied. The first groups of a deformation cohomology are constructed and several
Recent work has shown that, with the help of the Theory of Characteristic Modes (TCM), minor modifications of the terminal chassis can facilitate the design of orthogonal MIMO antennas with viable bandwidth at frequencies below 1 GHz. Herein, a new framework is proposed to further exploit TCM to enhance the performance of the orthogonal MIMO antennas. By correlating the characteristic currents and
AIMS/HYPOTHESIS: Voltage-gated calcium channels of the L-type have been shown to be essential for rodent pancreatic beta cell function, but data about their presence and regulation in humans are incomplete. We therefore sought to elucidate which L-type channel isoform is functionally important and its association with inherited diabetes-related phenotypes. METHODS: Beta cells of human islets from
Migraine attacks occur spontaneously in those who suffer from the condition, but migraine-like attacks can also be induced artificially by a number of substances. Previously published evidence makes the meninges a likely source of migraine related pain. This article investigates the effect of several vasodilators on meningeal arteries in order to find a connection between the effect of a substance
Glial cell line derived neurotrophic factor (GDNF) has great potential to treat Parkinson's disease (PD). However, constitutive expression of GDNF can over time lead to side effects. Therefore, it would be useful to regulate GDNF expression. Recently, a new gene inducible system using destabilizing domains (DD) from E. coil dihydrofolate reductase (DHFR) has been developed and characterized. The a
Purpose: Eddy current induced velocity offsets are of concern for accuracy in cardiovascular magnetic resonance (CMR) volume flow quantification. However, currently known theoretical aspects of eddy current behavior have not led to effective guidelines for the optimization of flow quantification sequences. This study is aimed at identifying correlations between protocol parameters and the resultin
Six vaccine formulations containing AS02(V) or alum (aluminum phosphate [AlPO4]) adjuvant with pneumococcal proteins, pneumococcal histidine triad D (PhtD), and/or detoxified pneumolysin (dPly), either as a polysaccharide carrier in an 8-valent pneumococcal conjugate vaccine (8PCV) or as free (unconjugated) proteins, were evaluated in adults -65 to 85 years of age. In this phase I observer-blind s
The popliteal artery (PA) is, after aorta, the most common site for aneurysm formation. Why the PA is more susceptible than other peripheral muscular arteries is unknown. We hypothesized that the wall composition, which in turn affects wall properties, as well as the circumferential wall stress (WS) imposed on the arterial wall, might differ compared to other muscular arteries. The aim was to stud
With the rapid progress in the development of new clinical biomarkers there is an unmet need of fast and sensitive multiplex analysis methods for disease specific protein monitoring. Immunoaffinity extraction integrated with matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) analysis offers a route to rapid and sensitive protein analysis and potentially multiplex biomarker an
Sung in Christian liturgies from the earliest period, biblical Odes—a set of songs excerpted from the biblical and apocryphal books—were central to emerging Christian practices and texts, yet their significance as textual witnesses has rarely been studied. Overlooked by text critics and editors, the Odes have largely been omitted from contemporary critical editions of the biblical books, including
Abstract in UndeterminedA recent governmental report has suggested that the notion of insanity, which has not been a relevant concept in Swedish criminal law for the last 50years, should be reintroduced into the criminal justice system. This move has generated a debate over the most appropriate criteria to be included in a legal standard for insanity. We consider the fundamental question of whethe
Recent multi-stage genome-wide association studies (GWAS) have identified single nucleotide polymorphisms (SNPs) that are robustly associated with chronic lymphocytic leukaemia (CLL) risk. Given that most of these SNPs map to non-coding regions of the genome, it suggests that the functional basis of many GWAS signals will be through differential gene expression. By referencing publically accessibl
