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Methods and Tools for Co-Simulation of Dynamic Systems with the Functional Mock-up Interface

Popular Abstract in Swedish Utveckling av nya industriella produkter sker allt oftare med hjälp av datormodeller. Dessa modeller beskriver fysiken för respektive produkt, vilket exempelvis kan vara en bil eller ett kraftverk. Med hjälp av modellerna kan en stor del av analyserna på de framtida produkterna ske med hjälp av datorer, varför färre prototyper behöver konstrueras, vilket medför kortare Simulation of coupled dynamical systems, where the subsystems are bundled with their own internal solver, is important in industry. This is due to that in many cases, with complex systems, this is the only viable option. In this setting, the dynamics of each system is hidden and information between subsystems is exchanged through sampled inputs and outputs, a weakly coupled system. While a new ind

Word stress in Romanian

The issue of word stress has not been the subject of any detailed analysis in traditional works on Romanian. It is generally assumed that stress is not predictable. The generalizations that have been made concerning stress placement are, however, made on the basis of observations of surface forms. Mallinson 1987:300 says that “stress is free and variable, giving rise to doublets: m'odele ‘the fash

Effect of a primary health-care-based controlled trial for cardiorespiratory fitness in refugee women.

BACKGROUND: Refugee women have a high risk of coronary heart disease with low physical activity as one possible mediator. Furthermore, cultural and environmental barriers to increasing physical activity have been demonstrated. The aim of the study was to evaluate the combined effect of an approximate 6-month primary health care- and community-based exercise intervention versus an individual writte

Immunology of beta-Cell Destruction.

The pancreatic islet beta-cells are the target for an autoimmune process that eventually results in an inability to control blood glucose due to the lack of insulin. The different steps that eventually lead to the complete loss of the beta-cells are reviewed to include the very first step of a triggering event that initiates the development of beta-cell autoimmunity to the last step of appearance

Spatiotemporal QRST cancellation techniques for analysis of atrial fibrillation

A new method for QRST cancellation is presented for the analysis of atrial fibrillation in the surface electrocardiogram (ECG). The method is based on a spatiotemporal signal model which accounts for dynamic changes in QRS morphology caused, e.g., by variations in the electrical axis of the heart. Using simulated atrial fibrillation signals added to normal ECGs, the results show that the spatiotem

TFEB-mediated autophagy rescues midbrain dopamine neurons from α-synuclein toxicity.

The aggregation of α-synuclein plays a major role in Parkinson disease (PD) pathogenesis. Recent evidence suggests that defects in the autophagy-mediated clearance of α-synuclein contribute to the progressive loss of nigral dopamine neurons. Using an in vivo model of α-synuclein toxicity, we show that the PD-like neurodegenerative changes induced by excess cellular levels of α-synuclein in nigral

Search for direct pair production of the top squark in all-hadronic final states in proton-proton collisions at=8 TeV with the ATLAS detector

The results of a search for direct pair production of the scalar partner to the top quark using an integrated luminosity of 20.1 fb(-1) of proton-proton collision data at = 8 TeV recorded with the ATLAS detector at the LHC are reported. The top squark is assumed to decay via or , where denotes the lightest neutralino (chargino) in supersymmetric models. The search targets a fully-hadronic final st

MYC inhibition induces metabolic changes leading to accumulation of lipid droplets in tumor cells

The MYC genes are the most frequently activated oncogenes in human tumors and are hence attractive therapeutic targets. MYCN amplification leads to poor clinical outcome in childhood neuroblastoma, yet strategies to modulate the function of MYCN do not exist. Here we show that 10058-F4, a characterized c-MYC/Max inhibitor, also targets the MYCN/Max interaction, leading to cell cycle arrest, apopto

The great dichotomy of the Solar System: Small terrestrial embryos and massive giant planet cores

The basic structure of the Solar System is set by the presence of low-mass terrestrial planets in its inner part and giant planets in its outer part. This is the result of the formation of a system of multiple embryos with approximately the mass of Mars in the inner disk and of a few multi-Earth-mass cores in the outer disk, within the lifetime of the gaseous component of the protoplanetary disk.

The influence of calibration method and eye physiology on eyetracking data quality

Abstract in UndeterminedRecording eye movement data with high quality is often a prerequisite for producing valid and replicable results and for drawing well-founded conclusions about the oculomotor system. Today, many aspects of data quality are often informally discussed among researchers but are very seldom measured, quantified, and reported. Here we systematically investigated how the calibrat

Moisture transport properties of lime-hemp concrete determined over the complete moisture range

To determine the durability of a lime-hemp concrete (LHC) wall and its resistance to driving rain, moisture conditions inside the wall have to be modelled. As model input, moisture transport properties were determined. Two LHC mixes were studied. Cup tests provided moisture diffusivity results at relative humidity (RH) values up to 95%. Capillary water uptake tests provided results for the interva

The effects of pH and disturbance on the bryophyte flora in calcareous sandy grasslands

The unique flora and fauna of calcareous sandy grasslands is threatened by acidification, eutrofication and changed land use. Restoration experiments in such grasslands in southern Sweden, including deep and shallow soil perturbation, allowed us to examine the effects of pH and disturbance on the bryophyte flora. We also studied natural pH and disturbance gradients in order to compare the natural

Not all IGHV3-21 chronic lymphocytic leukemias are equal: prognostic considerations.

An unresolved issue in chronic lymphocytic leukemia (CLL) is whether IGHV3-21 gene usage, in general, or the expression of stereotyped B-cell receptor immunoglobulin defining subset #2 (IGHV3-21/IGLV3-21), in particular, determines outcome for IGHV3-21-utilizing cases. We reappraised this issue in 8593 CLL patients of whom 437 (5%) used the IGHV3-21 gene with 254/437 (58%) classified as subset #2.

Assessing and Rewarding Excellent Academic Teachers for the benefit of an Organisation.

In this article we describe and analyse a system for rewarding excellence in university teaching developed at the Faculty of Engineering at Lund University in Sweden. Individual teachers are rewarded for the effort they invest in the support of student learning. However, it is the organization that establishes a reward system and it does so for developmental purposes. These two purposes, individua

Evidence of concurrentlocal adaptation and high phenotypic plasticityin a polar microeukaryote.

Here we investigated whether there is evidence of local adaptation in strains of an ancestrallymarine dinoflagellate to the lacustrine environment they now inhabit(optimal genotypes) and/orif they have evolved phenotypic plasticity (a range of phenotypes). Eleven strains of Polarella glacialis were isolated and cultured from three different environments: the polar seas, ahyposaline,and a hypersali

Effects of a modular two-step ozone-water and annealing process on silicon carbide graphene

By combining ozone and water, the effect of exposing epitaxial graphene on silicon carbide to an aggressive wet-chemical process has been evaluated after high temperature annealing in ultra high vacuum. The decomposition of ozone in water produces a number of oxidizing species, however, despite long exposure times to the aqueous-ozone environment, no graphene oxide was observed after the two-step