Search results

Background: Previous studies have indicated that vitamin K deficiency is common in non-bleeding critically ill patients with slightly prolonged prothrombin time-international normalized ratio (PT-INR). It has never been investigated thoroughly whether the administration of vitamin K to these patients could affect their PT-INR. Therefore, the aim of this registry study was to evaluate changes in PTBackground Previous studies have indicated that vitamin K deficiency is common in non-bleeding critically ill patients with slightly prolonged prothrombin time-international normalized ratio (PT-INR). It has never been investigated thoroughly whether the administration of vitamin K to these patients could affect their PT-INR. Therefore, the aim of this registry study was to evaluate changes in PT-

Multinational enterprises have outsourced production and distribution to layers of subsidiaries and contractors to expand into new markets and increase profitability. This compartmentalization of the enterprise is facilitated by company laws and has resulted in risk shifting, excessive risk taking and lack of remediation for those injured. Company laws in virtually all jurisdictions allow for corp

This chapter accounts for the special context of mining and discusses what “respecting” human rights means in the mining industry. The aim of the chapter is to clarify the relationship between social investments and respect for human rights in a context characterised by the disruption mining operations cause and weaker local capacities to cope with mining. Three questions are raised herein: Are so

The article examines reporting laws to determine if and how these laws shape corporate conduct and protect human rights. Since 2010 a wave of laws with extraterritorial effects has appeared as home states of multinationals began to mandate social disclosures. However, opinions as to their importance differ and some wonder whether these transparency laws are ‘a hollow victory’. What is the evidence

The use of scientific knowledge for society development requires enabling frameworks that allow the connection between knowledge production and use. STI policies and institutional arrangement are seen as a point of departure for such enabling frameworks. However, there is a need for understanding how individual countries are addressing the STI policies and institutional related issues as a means f

The effect of Cu on three different microbial endpoints was studied using different Cu sources, in order to check the usefulness of pure Cu salts to estimate the toxicity of commercial Cu fungicides on soil microbes. Cu additions caused similar dose-response curves of substrate induced respiration (SIR) decreases regardless of Cu source, i.e. the use of pure Cu salts to estimate the effect of Cu f

Value creation and appropriation are much-studied processes in business and management fields. However, both academia and business practice have traditionally focused on how value is created and appropriated in the economic context and by economic actors. This overemphasis on economic logic has created institutionalized asymmetries in managing the relationship between business, society and ecologi

This study evaluates a clinically applicable lentiviral vector for treatment of Gaucher disease type 1. Hematopoietic stem cells transduced with the vector and transplanted into a mouse model successfully halted or reversed pathology. These data were used as proof-of-concept for regulatory filing enabling the commencement of an international phase 1/2 clinical trial.

Co-optimization of urban morphology and distributed energy systems is key to curb energy consumption and optimally exploit renewable energy in cities. Currently available optimization techniques focus on either buildings or energy systems, mostly neglecting the impact of their interactions, which limits the renewable energy integration and robustness of the energy infrastructure; particularly in e

Objective: To explore diagnoses of postpartum haemorrhage following vaginal birth, in relation to socio-demographic and obstetrical data from women who gave birth at term, in Sweden, during the years 2005–2015. Study design: A register-based cohort study was carried out, describing and comparing socio-demographic variables, obstetric variables and infant variables in 52 367 cases of diagnosed post

A novel sliding vane rotary compressor with a rotating cylinder is proposed in this paper. The sliding vane dynamics analysis reveals that, compared with the traditional compressor, the friction loss at the sliding vane tips and between rotor and cylinder can be reduced to 0.25% and 10.23%. To numerically investigate the internal flow mechanism, a reliable three-dimensional simulation method is de

Alterations in gut endocrine cells and hormone levels have been measured in patients with irritable bowel syndrome (IBS). The hypothesis of the present study was that hormone levels would change after 4 weeks of a starch- and sucrose-reduced diet (SSRD) intervention corresponding to decreased carbohydrate intake and symptoms. Among 105 IBS patients from primary and tertiary healthcare, 80 were ran

Malfunction and amyloid formation of the Islet Amyloid Polypeptide (IAPP) are factors contributing to Type 2 diabetes. Unravelling the mechanism of IAPP aggregate formation may forward our understanding of this process and its effect on pancreatic β-islet cell. Such mechanistic studies require access to sequence homogeneous and highly pure IAPP. Here we present a new facile protocol for the produc

Packed beds with methane steam reforming reaction (MSR) can be used as thermochemical storage devices. The packing configuration can have a significant effect on the flow distribution which will further influence the heat/mass transfer, dispersion and reaction characteristics. In the present paper, the hydraulic, dispersion, heat/mass transfer and the MSR reaction properties are investigated in pa

We investigate the origin of close-in planets and related phenomena orbiting white dwarfs (WDs), which are thought to originate from orbits more distant from the star. We use the planetary architectures of the 75 multiple-planet systems (four, five, and six planets) detected orbiting main-sequence stars to build 750 dynamically analogous templates that we evolve to the WD phase. Our exploration of

Maintaining soil health is integral to agricultural production, and the archaeological record contains multiple lines of palaeoclimatic and palaeoenvironmental proxy evidence that can contribute to the understanding and analysis of long-term trajectories of change that are key for contextualizing 21st century global environmental challenges. Soil is a capital resource and its nutrient balance is m

Background: Second primary cancers (SPCs) are increasing due to improving survival in first primary cancers. Previous studies on SPCs in renal cell carcinoma (RCC) have focused on treatment and other risk factors, but data of RCC as an SPC are scarce. Objective: In this study, we want to elucidate the risk for any SPC after RCC, and in reverse order, for RCC as an SPC after any cancer. We addition

The matched window reassigned spectrogram relocates all signal energy of an oscillating transient to the time- and frequency locations, resulting in a sharp peak in the time-frequency plane. However, previous research has shown that the method may result in split energy peaks for close components and in high noise levels, and the peak energy is then erroneously estimated. With use of novel knowled